Microelectronic circuit emulating Hydrogen Bonding Network of Green Fluorescent Protein

Hydrogen Bonding Network in active site of wild type Green Fluorescent Protein during the A→A* state is modeled. A microelectronic equivalent circuit is developed on its basis to emulate the operational principle of the Hydrogen Bonding Network. It is coded in Matlab to investigate its static and dy...

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Bibliographic Details
Published in:	2016 XXV International Scientific Conference Electronics (ET) pp. 1 - 4
Main Authors:	Rusev, Rostislav Pavlov, Angelov, George Vasilev, Gieva, Elitsa Emilova, Atanasov, Boris Petkov, Hristov, Marin Hristov
Format:	Conference Proceeding
Language:	English
Published:	IEEE 01-09-2016
Subjects:	Bonding Fluorescence Green Fluorescent Protein (GFP) Hydrogen Hydrogen bonding networks (HBN) Integrated circuit modeling Mathematical model microelectronic circuit Proteins proton transfer characteristics Protons
Online Access:	Get full text
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Summary:	Hydrogen Bonding Network in active site of wild type Green Fluorescent Protein during the A→A* state is modeled. A microelectronic equivalent circuit is developed on its basis to emulate the operational principle of the Hydrogen Bonding Network. It is coded in Matlab to investigate its static and dynamic behavior. Output characteristics of static analysis are similar to inversed tunnel diode. The dynamic analysis show that the circuit can operate as amplifier, modulator and amplitude limiter.
DOI:	10.1109/ET.2016.7753511