Search Results - "Atanasov, Boris"

Evolutionary trajectory of receptor binding specificity and promiscuity of the spike protein of SARS‐CoV‐2 by Planchais, Cyril, Reyes‐Ruiz, Alejandra, Lacombe, Robin, Zarantonello, Alessandra, Lecerf, Maxime, Revel, Margot, Roumenina, Lubka T., Atanasov, Boris P., Mouquet, Hugo, Dimitrov, Jordan D.

“…SARS‐CoV‐2 infects cells by attachment to its receptor—the angiotensin converting enzyme 2 (ACE2). Regardless of the wealth of structural data, little is known…”
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The key role of E418 carboxyl group in the formation of Nt.BspD6I nickase active site: Structural and functional properties of Nt.BspD6I E418A mutant by Artyukh, Rimma I., Kachalova, Galina S., Yunusova, Alfiya K., Fatkhullin, Bulat F., Atanasov, Boris P., Perevyazova, Tatyana A., Popov, Alexander N., Gabdulkhakov, Azat G., Zheleznaya, Ludmila A.

“…The mutated nickase Nt.BspD6I E418A has been obtained by site-directed mutagenesis. The purified protein has been crystallized, and its spatial structure has…”
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PHEMTO: protein pH-dependent electric moment tools by Kantardjiev, Alexander A, Atanasov, Boris P

“…PHEMTO (protein pH-dependent electric moment tools) is released in response to the high demand in protein science community for evaluation of electrostatic…”
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Heme Interacts with C1q and Inhibits the Classical Complement Pathway by Roumenina, Lubka T., Radanova, Maria, Atanasov, Boris P., Popov, Krastio T., Kaveri, Srinivas V., Lacroix-Desmazes, Sébastien, Frémeaux-Bacchi, Véronique, Dimitrov, Jordan D.

“…C1q is the recognition subunit of the first component of the classical complement pathway. It participates in clearance of immune complexes and apoptotic cells…”
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PHEPS: web-based pH-dependent Protein Electrostatics Server by Kantardjiev, Alexander A., Atanasov, Boris P.

“…PHEPS (pH-dependent Protein Electrostatics Server) is a web service for fast prediction and experiment planning support, as well as for correlation and…”
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Kinetics and thermodynamics of interaction of coagulation factor VIII with a pathogenic human antibody by Dimitrov, Jordan D., Roumenina, Lubka T., Andre, Sebastien, Repesse, Yohann, Atanasov, Boris P., Jacquemin, Marc, Saint-Remy, Jean-Marie, Bayry, Jagadeesh, Kaveri, Srinivas V., Lacroix-Desmazes, Sebastien

“…Replacement therapy in hemophilia A with exogenous coagulation factor VIII (FVIII) often results in the development of FVIII-neutralizing antibodies, referred…”
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Role of Ca2+ in the Electrostatic Stability and the Functional Activity of the Globular Domain of Human C1q by Roumenina, Lubka T, Kantardjiev, Alexandar A, Atanasov, Boris P, Waters, Patrick, Gadjeva, Mihaela, Reid, Kenneth B. M, Mantovani, Alberto, Kishore, Uday, Kojouharova, Mihaela S

“…C1q is the recognition subunit of the classical pathway of the complement system and a major connecting link between classical pathway-driven innate immunity…”
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Protonation of the β -lactam Nitrogen Is the Trigger Event in the Catalytic Action of Class A β -lactamases by Atanasov, Boris P., Mustafi, Devkumar, Makinen, Marvin W.

“…The pH dependence of the pKavalues of all ionizable groups and of the electrostatic potential at grid points corresponding to catalytically important atoms in…”
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Structure of glycosylated Cu/Zn-superoxide dismutase from Kluyveromyces yeast NBIMCC 1984 by Dolashka-Angelova, Pavlina, Moshtanska, Vesela, Kujumdzieva, Anna, Atanasov, Boris, Petrova, Vencislava, Voelter, Wolfgang, Beeumen, Jozef Van

“…The primary structure of Cu/Zn-superoxide dismutase from Kluyveromyces marxianus NBIMCC 1984 was elucidated by N-terminal sequence analysis of the intact…”
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Mutational Analyses of the Recombinant Globular Regions of Human C1q A, B, and C Chains Suggest an Essential Role for Arginine and Histidine Residues in the C1q-IgG Interaction by Kojouharova, Mihaela S, Gadjeva, Mihaela G, Tsacheva, Ivanka G, Zlatarova, Aleksandra, Roumenina, Liubka T, Tchorbadjieva, Magdalena I, Atanasov, Boris P, Waters, Patrick, Urban, Britta C, Sim, Robert B, Reid, Kenneth B. M, Kishore, Uday

“…The first step in the activation of the classical complement pathway by immune complexes involves the binding of the globular domain (gC1q) of C1q to the Fc…”
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Glycan structures and antiviral effect of the structural subunit RvH2 of Rapana hemocyanin by Dolashka, Pavlina, Velkova, Ludmyla, Shishkov, Stoyan, Kostova, Kalina, Dolashki, Aleksander, Dimitrov, Ivan, Atanasov, Boris, Devreese, Bart, Voelter, Wolfgang, Van Beeumen, Jozef

“…3D Model of functional unit RvH2-e and hydrogen-bonding pattern and van der Waals contacts of the RvH2-e and HSV. Molluscan hemocyanins are very large…”
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Thermal Unfolding of the DNA-binding Protein Sso7d from the HyperthermophileSulfolobus solfataricus by Knapp, Stefan, Karshikoff, Andrej, Berndt, Kurt D., Christova, Petya, Atanasov, Boris, Ladenstein, Rudolf

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Structural analysis and molecular modeling of the RvH2-e functional unit of Rapana venosa hemocyanin by Velkova, Ludmila, Dolashka, Pavlina, Dolashki, Aleksander, Voelter, Wolfgang, Atanasov, Boris

“…Rapana venosa hemocyanin (RvH), a circulating glycoprotein of the marine snail, has a complex structure. To provide details on the stability of the protein,…”
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Disoxaril Mutants of Coxsackievirus B1: Phenotypic Characteristics and Analysis of the Target VP1 Gene by Nikolova, Ivanka, Galabov, Angel S., Petkova, Rumena, Chakarov, Stoyan, Atanasov, Boris

“…Disoxaril inhibits enterovirus replication by binding to the hydrophobic pocket within the VP1 coat protein, thus stabilizing the virion and blocking its…”
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Structural analysis and molecular modelling of the Cu/Zn-SOD from fungal strain Humicola lutea 103 by Dolashka, Pavlina, Moshtanska, Vesela, Dolashki, Aleksander, Velkova, Lyudmila, Rao, Gita Subba, Angelova, Maria, Betzel, Christian, Voelter, Wolfgang, Atanasov, Boris

“…[Display omitted] ► Reversibility of glycosylated Humicola lutea Cu/Zn-SOD was determined by CD spectroscopy. ► In this communication we report the thermal…”
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Reversibility and “pH– T phase diagrams” of Rapana venosa hemocyanin and its structural subunits by Dolashki, Alexandar, Velkova, Lyudmila, Atanasov, Boris, Voelter, Wolfgang, Stevanovic, Stefan, Schwarz, Heinz, Di Muro, Paolo, Dolashka-Angelova, Pavlina

“…We have studied the stability and reassociation behaviour of native molecules of Rapana venosa hemocyanin and its two subunits, termed RvH1 and RvH2. In the…”
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Disoxaril Mutants of Coxsackievirus B1: Phenotypic Characteristics and Analysis of the Target VP1 Gene by Nikolova, I., Galabov, A. S., Petkova, R., Chakarov, S., Atanasov, B.

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Dissection of the C1q–C-reactive protein interaction—A model for understanding the versatile C1q binding to target molecules by Roumenina, Lubka T., Popov, Krastio, Radanova, Maria, Gaboriaud, Christine, Frémeaux-Bacchi, Veronique, Atanasov, Boris

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Escaping Development of Drug-Resistant Mutants: Basis for Effective Chemotherapy of Enterovirus Infections by Galabov, Angel S., Vassileva-Pencheva, Ralitsa, Nikolova, Ivanka, Atanasov, Boris

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Complement C1q-target proteins recognition is inhibited by electric moment effectors by Roumenina, Lubka, Bureeva, Svetlana, Kantardjiev, Alexander, Karlinsky, David, Andia-Pravdivy, Julian E., Sim, Robert, Kaplun, Alexander, Popov, Michael, Kishore, Uday, Atanasov, Boris

“…Classical complement pathway is an important innate immune mechanism, which is usually triggered by binding of C1q to immunoglobulins, pentraxins and other…”
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