Search Results - "Atabey, Nese"

Elevated hepatocyte growth factor expression as an autocrine c‐Met activation mechanism in acquired resistance to sorafenib in hepatocellular carcinoma cells by Firtina Karagonlar, Zeynep, Koc, Dogukan, Iscan, Evin, Erdal, Esra, Atabey, Neşe

“…Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and the third leading cause of cancer‐related deaths worldwide. Limitations in…”
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Role of Albumin in Growth Inhibition in Hepatocellular Carcinoma by Bağırsakçı, Ezgi, Şahin, Eren, Atabey, Neşe, Erdal, Esra, Guerra, Vito, Carr, Brian I

“…Levels of serum albumin have recently emerged, together with C-reactive protein, as an important prognostic indicator for hepatocellular carcinoma (HCC). It…”
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lncRNA HOTAIR overexpression induced downregulation of c-Met signaling promotes hybrid epithelial/mesenchymal phenotype in hepatocellular carcinoma cells by Topel, Hande, Bagirsakci, Ezgi, Comez, Dehan, Bagci, Gulsun, Cakan-Akdogan, Gulcin, Atabey, Nese

“…Epithelial-to-mesenchymal transition (EMT) and mesenchymal-to-epithelial transition (MET) are both reversible processes, and regulation of phenotypical…”
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Influence of follicular fluid GDF9 and BMP15 on embryo quality by Gode, Funda, M.D, Gulekli, Bulent, M.D, Dogan, Erbil, M.D, Korhan, Peyda, M.Sc, Dogan, Seda, M.Sc, Bige, Ozgur, M.D, Cimrin, Dilek, M.D, Atabey, Nese, Ph.D

“…Objective To evaluate the association between follicular fluid levels of propeptide and mature forms of growth differentiation factor (GDF) 9 and bone…”
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Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells by Yuzugullu, Haluk, Benhaj, Khemais, Ozturk, Nuri, Senturk, Serif, Celik, Emine, Toylu, Asli, Tasdemir, Nilgun, Yilmaz, Mustafa, Erdal, Esra, Akcali, Kamil Can, Atabey, Nese, Ozturk, Mehmet

“…beta-catenin mutations that constitutively activate the canonical Wnt signaling have been observed in a subset of hepatocellular carcinomas (HCCs). These…”
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Reciprocal activating crosstalk between c-Met and caveolin 1 promotes invasive phenotype in hepatocellular carcinoma by Korhan, Peyda, Erdal, Esra, Kandemiş, Emine, Cokaklı, Murat, Nart, Deniz, Yılmaz, Funda, Can, Alp, Atabey, Neşe

“…c-Met, the receptor for Hepatocyte Growth Factor (HGF), overexpressed and deregulated in Hepatocellular Carcinoma (HCC). Caveolin 1 (CAV1), a plasma membrane…”
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Evaluation of androgen receptor and androgen receptor splice-variant 7 in bladder cancer; a novel approach into an ancient topic by Sarıkaya, Ege Alper, Korhan, Peyda, Incir, Canet, Yıldız, Alperen H., Deger, Dogan M., Özer, Selçuk M., Tuncok, Yesim, Ergor, Gul, Islakoğlu, Yasemin Ö., Sen, Volkan, Bozkurt, Ozan, Atabey, Neşe, Esen, Adil A.

“…Purpose The contribution of androgen receptors (AR) on bladder cancer has been demonstrated in pre-clinical studies, however in clinical studies, only the…”
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Increased telomerase activity in major depressive disorder with melancholic features: Possible role of pro-inflammatory cytokines and the brain-derived neurotrophic factor by Bürhan-Çavuşoğlu, Pınar, İscan, Evin, Güneş, Ayşim, Atabey, Neşe, Alkın, Tunç

“…The biological mechanisms responsible for depression symptoms are not yet understood. For this reason, it is important to reveal the etiopathogenetic…”
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Active form of AKT controls cell proliferation and response to apoptosis in hepatocellular carcinoma by KUNTER, IMGE, ERDAL, ESRA, NART, DENIZ, YILMAZ, FUNDA, KARADEMIR, SEDAT, SAGOL, OZGUL, ATABEY, NESE

“…Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related mortality worldwide. Deregulation of the AKT signaling pathway has been found…”
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The role of resistin on metabolic syndrome‐induced erectile dysfunction and the possible therapeutic effect of Boldine by Kara, Erkan, Kahraman, Erkan, Dayar, Ezgi, Yetik Anacak, Gunay, Demir, Omer, Gidener, Sedef, Atabey, Nese, Durmus, Nergiz

“…Background Resistin is known as a potential mediator of obesity‐associated insulin resistance. The high resistin level disrupts nitric oxide (NO)‐mediated…”
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Heparin inhibits Hepatocyte Growth Factor induced motility and invasion of hepatocellular carcinoma cells through early growth response protein 1 by Ozen, Evin, Gozukizil, Aysim, Erdal, Esra, Uren, Aykut, Bottaro, Donald P, Atabey, Nese

“…The Hepatocyte Growth Factor (HGF)/c-Met signaling pathway regulates hepatocyte proliferation, and pathway aberrations are implicated in the invasive and…”
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The regulatory role of heparin on c-Met signaling in hepatocellular carcinoma cells by İşcan, Evin, Güneş, Aysim, Korhan, Peyda, Yılmaz, Yeliz, Erdal, Esra, Atabey, Neşe

“…The role of heparin as an anticoagulant is well defined; however, its role in tumorigenesis and tumor progression is not clear yet. Some studies have shown…”
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A Comparison of the Effectiveness of Silibinin and Resveratrol in Preventing Alpha‐Amanitin‐Induced Hepatotoxicity by Sahin, Aynur, Arici, Mualla Aylin, Yilmaz, Yeliz, Kalkan, Sule, Durmus, Nergiz, Ergur, Bekir Ugur, Yakut Aksu, Ilkay, Atabey, Neşe, Tuncok, Yesim

“…Amanita phalloides species mushrooms containing alpha‐amanitin (α‐AMA) are responsible for the majority of fatal mushroom intoxications and can lead to severe…”
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Ezrin Enhances EGFR Signaling and Modulates Erlotinib Sensitivity in Non–Small Cell Lung Cancer Cells by Saygideğer-Kont, Yasemin, Minas, Tsion Zewdu, Jones, Hayden, Hour, Sarah, Çelik, Haydar, Temel, Idil, Han, Jenny, Atabey, Nese, Erkizan, Hayriye Verda, Toretsky, Jeffrey A, Üren, Aykut

“…Abstract Ezrin is a scaffolding protein that is involved in oncogenesis by linking cytoskeletal and membrane proteins. Ezrin interacts with epidermal growth…”
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A Novel Function for KLF4 in Modulating the De-differentiation of EpCAM - /CD133 - nonStem Cells into EpCAM + /CD133 + Liver Cancer Stem Cells in HCC Cell Line HuH7 by Karagonlar, Zeynep Firtina, Akbari, Soheil, Karabicici, Mustafa, Sahin, Eren, Avci, Sanem Tercan, Ersoy, Nevin, Ates, Kıvılcım Eren, Balli, Tugsan, Karacicek, Bilge, Kaplan, Kubra Nur, Celiker, Canan, Atabey, Nese, Erdal, Esra

“…The complex and heterogeneous nature of hepatocellular carcinoma (HCC) hampers the identification of effective therapeutic strategies. Cancer stem cells (CSCs)…”
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Differential expression of Caveolin-1 in hepatocellular carcinoma: correlation with differentiation state, motility and invasion by Cokakli, Murat, Erdal, Esra, Nart, Deniz, Yilmaz, Funda, Sagol, Ozgul, Kilic, Murat, Karademir, Sedat, Atabey, Nese

“…Caveolin-1 is the main component of caveolae membrane structures and has different roles during tumorigenesis in different cancer types with varying expression…”
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Pleiotropic Effects of Heparins: From Clinical Applications to Molecular Mechanisms in Hepatocellular Carcinoma by Atabey, Neşe, Topel, Hande, Güneş, Ayşim, Bağırsakçı, Ezgi, Yılmaz, Yeliz, Korhan, Peyda, Carr, Brian I.

“…Hepatocellular carcinoma (HCC) is a major health problem worldwide and most cases are incurable because of late presentation. It is the most common primary…”
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Filamin a mediates HGF/c‐MET signaling in tumor cell migration by Zhou, Alex‐Xianghua, Toylu, Aslı, Nallapalli, Rajesh K., Nilsson, Gisela, Atabey, Neşe, Heldin, Carl‐Henrik, Borén, Jan, Bergo, Martin O., Akyürek, Levent M.

“…Deregulated hepatocyte growth factor (HGF)/c‐MET axis has been correlated with poor clinical outcome and drug resistance in many human cancers. Identification…”
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The levels of hepatocyte growth factor in serum and follicular fluid and the expression of c-Met in granulosa cells in patients with polycystic ovary syndrome by Şahin, Nur, M.D, Toylu, Asl, M.D., Ph.D, Gülekli, Bülent, M.D, Doğan, Erbil, M.D, Kovali, Müge, M.Sc, Atabey, Neşe, Ph.D

“…Objective To evaluate the levels of hepatocyte growth factor (HGF) in follicular fluid (FF) and the expression of c-Met in granulosa cells (GCs) with respect…”
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miR-181a-5p is downregulated in hepatocellular carcinoma and suppresses motility, invasion and branching-morphogenesis by directly targeting c-Met by Korhan, Peyda, Erdal, Esra, Atabey, Neşe

“…•miR-181a-5p directly targets c-Met via its 3′-UTR.•miR-181a-5p coordinates c-Met signaling pathway.•miR-181a-5p regulates migration, invasion and…”
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