Search Results - "Astre, C"

Inter- and intra-individual variability in transdermal fentanyl absorption in cancer pain patients by Solassol, Isabelle, Caumette, Laetitia, Bressolle, Françoise, Garcia, Frédéric, Thézenas, Simon, Astre, Cécile, Culine, Stéphane, Coulouma, Rémi, Pinguet, Frédéric

“…A transdermal therapeutic system (TTS) is recommended for use in chronic cancer pain, particularly in the advanced stages. The aim of this trial was to study…”
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Liquid Chromatography-Electrospray Mass Spectrometry Determination of Imatinib and Its Main Metabolite, N-Desmethyl-Imatinib in Human Plasma by Solassol, I., Bressolle, F., Philibert, L., Charasson, V., Astre, C., Pinguet, F.

“…The aim of this paper was to develop a specific and sensitive liquid chromatography/electrospray ionization mass spectrometry method for the determination of…”
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Population pharmacokinetics of melphalan, infused over a 24-hour period, in patients with advanced malignancies by MOUGENOT, Philippe, PINGUET, Frédéric, FABBRO, Michel, CULINE, Stéphane, POUJOL, Sylvain, ASTRE, Cécile, BRESSOLLE, Francoise

“…The objective of the present study was to characterize the population pharmacokinetics of melphalan infused over a 24-h period in patients with advanced…”
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Ozone Measurement with Passive Samplers:  Validation and Use for Ozone Pollution Assessment in Montpellier, France by Bernard, Nadine L, Gerber, Mariette J, Astre, Cecile M, Saintot, Monique J

“…The objective of this pilot study was to determine a way of assessing personal exposure to ozone (O3) for use in a study of O3 effects on health. Passive…”
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Salivary and plasma pharmacokinetics of topotecan in patients with metastatic epithelial ovarian cancer by Boucaud, M., Pinguet, F., Poujol, S., Romieu, G., Cupissol, D., Astre, C., Culine, S., Bressolle, F.

“…The comparative saliva/plasma pharmacokinetics of topotecan were investigated in 13 patients with metastatic epithelial ovarian cancer receiving topotecan…”
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Plasma and salivary pharmacokinetics of 5-fluorouracil (5-FU) in patients with metastatic colorectal cancer receiving 5-FU bolus plus continuous infusion with high-dose folinic acid by Joulia, J.M, Pinguet, F, Ychou, M, Duffour, J, Astre, C, Bressolle, F

“…The comparative saliva/plasma pharmacokinetics of 5-fluorouracil (5-FU) were investigated in 21 patients with metastatic colorectal cancer receiving high-dose…”
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Anal sphincter reconstruction by dynamic graciloplasty after abdominoperineal resection for cancer by Rouanet, P, Senesse, P, Bouamrirene, D, Toureille, E, Veyrac, M, Astre, C, Bacou, F

“…Chronic low-frequency electrical stimulation can safely transform fatiguing muscle into fatigue-resistant muscle. This fundamental discovery was used to…”
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Influence of the schedule of exposure on the cytotoxic effect of melphalan on human 8226 and A2780 cells by Pinguet, F, Bressolle, F, Culine, S, Fabbro, M, Astre, C, Chevillard, C

“…Melphalan was investigated for antitumoral activity using two schedules of exposure (solid versus sequential exposure) in two human cancer cell lines (8226 and…”
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Pharmacokinetics of high-dose intravenous melphalan in patients undergoing peripheral blood hematopoietic progenitor-cell transplantation by Pinguet, F, Martel, P, Fabbro, M, Petit, I, Canal, P, Culine, S, Astre, C, Bressolle, F

“…The pharmacokinetics of melphalan following high-dose (140 mg/m2) i.v. administration were determined in 20 patients with advanced malignancies undergoing…”
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Quantitation of Melphalan in Human Plasma by Liquid Chromatography and Solid Phase Extraction: Application to Pharmacokinetic Study by Poujol, S., Pinguet, F., Mougenot, P., Malosse, F., Fabbro, M., Culine, S., Astre, C., Bressolle, F.

“…A high-performance liquid chromatographic (HPLC) method for the determination of melphalan in human plasma was developed. This method involved a solid phase…”
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Long-term stability of 5-fluorouracil stored in PVC bags and in ambulatory pump reservoirs by Martel, P., Petit, J., Pinguet, F., Poujol, S., Astre, C., Fabbro, M.

“…Prolonged infusions of 5-fluorouracil (5FU) have been used since the early 1960s, but recently there has been a major resurgence of interest, partly because of…”
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SENSITIVE HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC FLUORESCENCE DETERMINATION OF TOPOTECAN IN HUMAN PLASMA AND PAROTID SALIVA by Boucaud, M., Pinguet, F., Poujol, S., Astre, C., Bressolle, F.

“…A sensitive and specific high performance liquid chromatographic (HPLC) method with fluorescence detection was developed and validated for the determination of…”
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Conservative treatment for low rectal carcinoma by local excision with or without radiotherapy by Rouanet, P, Saint Aubert, B, Fabre, J M, Astre, C, Liu, J Z, Dubois, J B, Joyeux, H, Solassol, C, Pujol, H

“…Thirty-seven patients with low rectal carcinoma were treated by transanal resection between January 1979 and December 1988. Adjuvant radiotherapy was used in…”
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Effects of moderate changes in protein intake on urinary albumin excretion in type I diabetic patients by Percheron, C, Colette, C, Astre, C, Monnier, L

“…We investigated the short-term effects of moderate increments or decrements of protein intake on albumin excretion rates of type I diabetic patients. Ten…”
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A Phase II study of 5-fluorouracil, leucovorin and cisplatin (FLP) for metastatic gastric cancer by Ychou, M., Astre, C., Rouanet, Ph, Fahbre, J.M., Saint-Aubert, B., Domergue, J., Ribard, D., Ciurana, A.J., Janbon, Ch, Pujol, H.

“…The modulation of 5-fluorouracil (5-FU) with folinic acid (leucovorin, LV) is more efficacious than 5-FU alone in the treatment of metastatic colorectal…”
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Stability of the principal cytostatic agents during storage at unusual temperatures by Martel, P., Pinguet, F., Petit, I., Poujol, S., Astre, C., Fabbro, M.

“…The aim of our study was to determine the stability of ten antineoplastic drugs stored in their initial package, in conditions of temperature which may be…”
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Relationship of serum cholesterol, dietary and plasma beta-carotene with lung cancer in male smokers by Scali, J, Astre, C, Segala, C, Gerber, M

“…It has been hypothesized that beta-carotene mediates the association between low serum cholesterol levels and increased risk of lung cancer. It follows from…”
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Effect of sodium chloride concentration and temperature on melphalan stability during storage and use by Pinguet, F, Martel, P, Rouanet, P, Fabbro, M, Astre, C

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Within-subjects seasonal variation and determinants of inter-individual variations of plasma beta-carotene by Saintot, M, Astre, C, Scali, J, Gerber, M

“…We studied determinants of plasma beta-carotene in a sample of 98 normal volunteers. Blood samples were collected and 4-day weighed dietary records kept for…”
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Bayesian Estimate of Vinorelbine Pharmacokinetic Parameters in Elderly Patients with Advanced Metastatic Cancer by GAUVIN, A, PINGUET, F, CULINE, S, ASTRE, C, GOMENI, R, BRESSOLLE, F

“…The objective of the present study was to determine the pharmacokinetic profile of vinorelbine in patients 65 years or older with metastatic cancer in…”
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