Search Results - "AstraZeneca"

Identification of C. elegans ASNA-1 domains and tissue requirements that differentially influence platinum sensitivity and growth control by Raj, Dorota, Podraza-Farhanieh, Agnieszka, Gallego, Pablo, Kao, Gautam, Naredi, Peter

“…ASNA1 plays an essential role in cisplatin chemotherapy response, type 2 diabetes, and heart disease. It is also an important biomarker in the treatment…”
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Plasma proteomic associations with genetics and health in the UK Biobank by Sun, Benjamin B., Chiou, Joshua, Traylor, Matthew, Benner, Christian, Hsu, Yi-Hsiang, Richardson, Tom G., Surendran, Praveen, Mahajan, Anubha, Robins, Chloe, Vasquez-Grinnell, Steven G., Hou, Liping, Kvikstad, Erika M., Burren, Oliver S., Davitte, Jonathan, Ferber, Kyle L., Gillies, Christopher E., Hedman, Åsa K., Hu, Sile, Lin, Tinchi, Mikkilineni, Rajesh, Pendergrass, Rion K., Pickering, Corran, Prins, Bram, Baird, Denis, Chen, Chia-Yen, Ward, Lucas D., Deaton, Aimee M., Welsh, Samantha, Willis, Carissa M., Lehner, Nick, Arnold, Matthias, Wörheide, Maria A., Suhre, Karsten, Kastenmüller, Gabi, Sethi, Anurag, Cule, Madeleine, Raj, Anil, Burkitt-Gray, Lucy, Melamud, Eugene, Black, Mary Helen, Fauman, Eric B., Howson, Joanna M. M., Kang, Hyun Min, McCarthy, Mark I., Nioi, Paul, Petrovski, Slavé, Scott, Robert A., Smith, Erin N., Szalma, Sándor, Waterworth, Dawn M., Mitnaul, Lyndon J., Szustakowski, Joseph D., Gibson, Bradford W., Miller, Melissa R., Whelan, Christopher D.

“…The Pharma Proteomics Project is a precompetitive biopharmaceutical consortium characterizing the plasma proteomic profiles of 54,219 UK Biobank participants…”
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Rare variant associations with plasma protein levels in the UK Biobank by Dhindsa, Ryan S., Burren, Oliver S., Sun, Benjamin B., Prins, Bram P., Matelska, Dorota, Wheeler, Eleanor, Mitchell, Jonathan, Oerton, Erin, Hristova, Ventzislava A., Smith, Katherine R., Carss, Keren, Wasilewski, Sebastian, Harper, Andrew R., Paul, Dirk S., Fabre, Margarete A., Runz, Heiko, Viollet, Coralie, Challis, Benjamin, Platt, Adam, Vitsios, Dimitrios, Ashley, Euan A., Whelan, Christopher D., Pangalos, Menelas N., Wang, Quanli, Petrovski, Slavé

“…Integrating human genomics and proteomics can help elucidate disease mechanisms, identify clinical biomarkers and discover drug targets 1 – 4 . Because…”
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Durability of protection and immunogenicity of AZD1222 (ChAdOx1 nCoV-19) COVID-19 vaccine over 6 months by Sobieszczyk, Magdalena E, Maaske, Jill, Falsey, Ann R, Sproule, Stephanie, Robb, Merlin L, Frenck, Jr, Robert W, Tieu, Hong-Van, Mayer, Kenneth H, Corey, Lawrence, Neuzil, Kathleen M, Tong, Tina, Brewinski Isaacs, Margaret, Janes, Holly, Bansal, Himanshu, Edwards, Lindsay M, Green, Justin A, Kelly, Elizabeth J, Shoemaker, Kathryn, Takas, Therese, White, Tom, Bhuyan, Prakash, Villafana, Tonya, Hirsch, And Ian

“…BackgroundWe report updated safety, efficacy, and immunogenicity of AZD1222 (ChAdOx1 nCoV-19) from an ongoing phase 3 trial.MethodsAdults at increased risk of…”
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The effect of temperature, storage time and collection method on biomethane potential of source separated household food waste by Nilsson Påledal, S., Hellman, E., Moestedt, J.

“…•Experiments to mimic storage of OFMSW performed in laboratory scale at 6 and 22 °C.•A recipe representative for OFMSW from households in Sweden was…”
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Linking antimicrobial resistance surveillance to antibiotic policy in healthcare settings: the COMBACTE-Magnet EPI-Net COACH project by Pezzani, Maria Diletta, Mazzaferri, Fulvia, Compri, Monica, Galia, Liliana, Mutters, Nico T, Kahlmeter, Gunnar, Zaoutis, Theoklis E, Schwaber, Mitchell J, Rodríguez-Baño, Jesús, Harbarth, Stephan, Tacconelli, Evelina

“…Abstract Objectives To systematically summarize the evidence on how to collect, analyse and report antimicrobial resistance (AMR) surveillance data to inform…”
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LKB1/STK11 Expression in Lung Adenocarcinoma and Associations With Patterns of Recurrence by Mitchell, Kyle G., Parra, Edwin R., Zhang, Jiexin, Nelson, David B., Corsini, Erin M., Villalobos, Pamela, Moran, Cesar A., Skoulidis, Ferdinandos, Wistuba, Ignacio I., Fujimoto, Junya, Roth, Jack A., Antonoff, Mara B., Lee, J. Jack, Vaporciyan, Ara A., Hofstetter, Wayne L., Mehran, Reza J., Swisher, Stephen G., Rice, David C., Sepesi, Boris, Walsh, Garrett L., Behrens, Carmen, Kalhor, Neda, Weissferdt, Annikka, Heymach, John V., Heymach, John V., AstraZeneca, Bayer, GlaxoSmithKline

“…Mutations in the serine/threonine kinase 11 (STK11)/liver kinase B1 (LKB1) have been implicated in mediating resistance to checkpoint blockade among patients…”
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Preliminary Study of Oxygen-Enhanced Longitudinal Relaxation in MRI: A Potential Novel Biomarker of Oxygenation Changes in Solid Tumors by O'Connor, James P.B., Ph.D., M.R.C.S, Naish, Josephine H., Ph.D, Parker, Geoff J.M., Ph.D, Waterton, John C., Ph.D, Watson, Yvonne, D.C.R, Jayson, Gordon C., Ph.D., F.R.C.P, Buonaccorsi, Giovanni A., Ph.D, Cheung, Sue, M.Sc, Buckley, David L., Ph.D, McGrath, Deirdre M., Ph.D, West, Catharine M.L., Ph.D, Davidson, Susan E., M.D., F.R.C.R, Roberts, Caleb, Ph.D, Mills, Samantha J., F.R.C.R, Mitchell, Claire L., M.R.C.P, Hope, Lynn, R.C.N, Ton, N. Chan, M.R.C.P, Jackson, Alan, Ph.D., F.R.C.R

“…Purpose There is considerable interest in developing non-invasive methods of mapping tumor hypoxia. Changes in tissue oxygen concentration produce proportional…”
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Immune correlates analysis of a phase 3 trial of the AZD1222 (ChAdOx1 nCoV-19) vaccine by Benkeser, David, Fong, Youyi, Janes, Holly E., Kelly, Elizabeth J., Hirsch, Ian, Sproule, Stephanie, Stanley, Ann Marie, Maaske, Jill, Villafana, Tonya, Houchens, Christopher R., Martins, Karen, Jayashankar, Lakshmi, Castellino, Flora, Ayala, Victor, Petropoulos, Christos J., Leith, Andrew, Haugaard, Deanne, Webb, Bill, Lu, Yiwen, Yu, Chenchen, Borate, Bhavesh, van der Laan, Lars W. P., Hejazi, Nima S., Carpp, Lindsay N., Randhawa, April K., Andrasik, Michele P., Kublin, James G., Isaacs, Margaret Brewinski, Makhene, Mamodikoe, Tong, Tina, Robb, Merlin L., Corey, Lawrence, Neuzil, Kathleen M., Follmann, Dean, Hoffman, Corey, Falsey, Ann R., Sobieszczyk, Magdalena, Koup, Richard A., Donis, Ruben O., Gilbert, Peter B.

“…In the phase 3 trial of the AZD1222 (ChAdOx1 nCoV-19) vaccine conducted in the U.S., Chile, and Peru, anti-spike binding IgG concentration (spike IgG) and…”
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Opportunities and Challenges of Swarm AI for Decentralized Clinical Research by Maria Palombini, Director, Healthcare and Life Sciences Practice, IEEE SA, Prof. Dr. Joachim L. Schultze, Director Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen e. V. (DZNE); Director, Genomics & Immunoregulation, LIMES-Institute, University of Bonn Germany, Krishnaprasad Shastry, Director, Distinguished Technologist, Hewlett Packard Enterprise (HPE), Vikram Shetty, Medical Director, Singapore and Asia Area Lung Cancer Lead, AstraZeneca

“…Swarm learning opens new opportunities for collaboration and innovation in clinical research where all members of the swarm have equal rights. Only algorithms…”
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Outcome of Initial Antibiotic Treatments Among Hospitalized Patients With Hospital- and Healthcare-Associated Bacterial Infections in Brazil: Findings of the RECOMMEND Study by Karve, Sudeep, Ryan, Kellie, Gaithersburg, AstraZeneca, Pascual, Esther, Peeters, Pascale, Rojas-Farreras, Sonia, Baelen, Elisa, Rodriguez-Bano, Jesus

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Sufficient control of heartburn in endoscopy negative heartburn trials by JUNGHARD, O, CARLSSON, R, LIND, T, ASTRAZENECA

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Sufficient control of heartburn in endoscopy negative heartburn trials by Junghard, Ola, Carlsson, Rolf, Lind, Tore, AstraZeneca

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Vitamin D fails to prevent serum starvation- or staurosporine-induced apoptosis in human and rat osteosarcoma-derived cell lines by Witasp, Erika, Gustafsson, Ann-Catrin, Cotgreave, Ian, Lind, Monica, Fadeel, Bengt

“…Previous studies have suggested that 1,25(OH) 2D 3, the active form of vitamin D 3, may increase the survival of bone-forming osteoblasts through an inhibition…”
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Drug interaction studies of esomeprazole with amoxicillin and clarithromycin by Andersson, Tommy, AstraZeneca, L.P., Rohss, Kerstin, Hassan-Alin, Mohammed

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Drug interaction studies of esomeprazole with amoxicillin and clarithromycin by ANDERSSON, T, ASTRAZENECA, L, ROHSS, K, HASSANALIN, M

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No evidence of glucocorticosteroid-induced apoptosis of airway epithelial cells In vivo by Miller-Larsson, Anna, Selroos, Olof

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Willingness to pay for relief of gastroesophageal reflux disease by Kleinman, Leah, Crawley, Joseph, L.P., AstraZeneca, Schmier, Jordana K., Ryan, Mandy, McIntosh, Emma, De Lissovoy, Gregory

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Health-related quality of life improves with GERD symptom resolution: Treatment effects by baseline severity by ZODET, M, JOSHUAGOTLIB, S, ASTRAZENECA, L, REVICKI, D, LEVINE, D, CRAWLEY, J

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Health-related quality of life improves with GERD symptom resolution: Treatment effects by baseline severity by Zodet, Marc W., Joshua-Gotlib, Sandra, AstraZeneca, L.P., Revicki, Dennis, Levine, Douglas, Crawley, Joseph A.

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