Search Results - "Aston, C. E."

A randomized controlled trial adding fluvastatin to peginterferon and ribavirin for naïve genotype 1 hepatitis C patients by Bader, T., Hughes, L. D., Fazili, J., Frost, B., Dunnam, M., Gonterman, A., Madhoun, M., Aston, C. E.

“…Summary Fluvastatin or simvastatin has demonstrable antiviral activity against hepatitis C virus (HCV) as monotherapy. The safety and efficacy of adding…”
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Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis by Gorry, MC, Gabbaizedeh, D, Furey, W, Gates, LK, Preston, RA, Aston, CE, Zhang, Y, Ulrich, C, Ehrlich, GD, Whitcomb, DC

“…BACKGROUND & AIMS: We recently identified a single R117H mutation in the cationic trypsinogen gene in several kindreds with an inherited form of acute and…”
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Reduced soluble receptor for advanced glycation end-products (sRAGE) scavenger capacity precedes pre-eclampsia in Type 1 diabetes by Yu, Y, Hanssen, KF, Kalyanaraman, V, Chirindel, A, Jenkins, AJ, Nankervis, AJ, Torjesen, PA, Scholz, H, Henriksen, T, Lorentzen, B, Garg, SK, Menard, MK, Hammad, SM, Scardo, JA, Stanley, JR, Wu, M, Basu, A, Aston, CE, Lyons, TJ

“…Please cite this paper as: Yu Y, Hanssen K, Kalyanaraman V, Chirindel A, Jenkins A, Nankervis A, Torjesen P, Scholz H, Henriksen T, Lorentzen B, Garg S, Menard…”
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Anti-angiogenic factors and pre-eclampsia in type 1 diabetic women by Yu, Y, Jenkins, A. J, Nankervis, A. J, Hanssen, K. F, Scholz, H, Henriksen, T, Lorentzen, B, Clausen, T, Garg, S. K, Menard, M. K, Hammad, S. M, Scardo, J. C, Stanley, J. R, Dashti, A, May, K, Lu, K, Aston, C. E, Wang, J. J, Zhang, S. X, Ma, J.-X, Lyons, T. J

“…Aims/hypothesis Elevated anti-angiogenic factors such as soluble fms-like tyrosine kinase 1 (sFlt1), a soluble form of vascular endothelial growth factor…”
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Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes by Yu, Y, Thorpe, S. R, Jenkins, A. J, Shaw, J. N, Sochaski, M. A, McGee, D, Aston, C. E, Orchard, T. J, Silvers, N, Peng, Y. G, McKnight, J. A, Baynes, J. W, Lyons, T. J

“…Aims/hypothesis We determined whether oxidative damage in collagen is increased in (1) patients with diabetes; (2) patients with diabetic complications; and…”
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A gene for hereditary pancreatitis maps to chromosome 7q35 by Whitcomb, DC, Preston, RA, Aston, CE, Sossenheimer, MJ, Barua, PS, Zhang, Y, Wong- Chong, A, White, GJ, Wood, PG, Gates, LK, Ulrich, C, Martin, SP, Post, JC, Ehrlich, GD

“…BACKGROUND & AIMS: Hereditary pancreatitis (HP) is an autosomal- dominant disorder with incomplete penetrance characterized by recurrent bouts of severe…”
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DNA Polymorphisms in Two Paraoxonase Genes (PON1 and PON2) Are Associated with the Risk of Coronary Heart Disease by Sanghera, Dharambir K., Aston, Christopher E., Saha, Nilmani, Kamboh, M. Ilyas

“…A common polymorphism at codon 192 in the human paraoxonase (PON) 1 gene has been shown to be associated with increased risk for coronary heart disease (CHD)…”
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Expression and penetrance of the hereditary pancreatitis phenotype in monozygotic twins by Amann, S T, Gates, L K, Aston, C E, Pandya, A, Whitcomb, D C

“…BACKGROUND Hereditary pancreatitis (HP) is a rare autosomal dominant disorder with variable expression and an overall lifetime penetrance of 80%. We…”
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Genetic screening of the lipoprotein lipase gene for mutations associated with high triglyceride/low HDL-cholesterol levels by RAZZAGHI, H, ASTON, C. E, HAMMAN, R. F, KAMBOH, M. I

“…The lipoprotein lipase (LPL) enzyme plays a major role in lipid metabolism, primarily by regulating the catabolism of triglyceride (TG)-rich lipoprotein…”
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Mortality benefit of statin use in traumatic spinal cord injury: a retrospective analysis by Stillman, M D, Aston, C E, Rabadi, M H

“…Study design: An observational study based on retrospective review of the medical charts and death records of 163 individuals with traumatic spinal cord…”
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Genetic Polymorphism of Paraoxonase and the Risk of Coronary Heart Disease by Sanghera, Dharambir K, Saha, Nilmani, Aston, Christopher E, Kamboh, M. Ilyas

“…Recent studies have implicated paraoxonase, an HDL-associated enzyme, in providing protection against LDL oxidation, thus affecting the risk of coronary heart…”
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Relationship of American Indian blood quantum with osteoporosis risk: a cross-sectional study of American Indian women in Oklahoma by Smith, B. J., Leyva, M. J., Stephens, L. D., Aston, C. E., Hermann, J., Payton, M., Baker, M. Z.

“…Summary Information regarding the prevalence and risk of osteoporosis among American Indian (AI) women is limited. This study showed that with increasing AI…”
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A randomized trial of dalteparin compared with ibuprofen for the treatment of superficial thrombophlebitis by RATHBUN, S. W., ASTON, C. E., WHITSETT, T. L.

“…Background: Superficial thrombophlebitis can produce pain and result in a deep vein thrombosis (DVT) if not treated. Conservative therapies including…”
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The effect of Covid-19 on pediatric surgical case volume by B.L. Junqueira, L. M. Taylor, C. E. Aston, B. Bewley, J. Mason, A. J. Rensing

“…Introduction The COVID-19 pandemic has had an unprecedented ef- fect on hospital systems. Policy changes lead to de- creased hospital visits as well as…”
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Lung cancer risk in families of nonsmoking probands: Heterogeneity by age at diagnosis by Yang, P., Schwartz, A.G., McAllister, A.E., Swanson, G.M., Aston, C.E.

“…In an earlier investigation, we did not detect a major genetic component to lung cancer in families of nonsmoking lung cancer probands. However, heterogeneity…”
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Linkage and Association between Inflammatory Bowel Disease and a Locus on Chromosome 12 by Duerr, Richard H., Barmada, M. Michael, Zhang, Leilei, Davis, Sean, Preston, Robert A., Chensny, Lara J., Brown, Jody L., Ehrlich, Garth D., Weeks, Daniel E., Aston, Christopher E.

“…Genetic epidemiological studies have shown that genetic factors are important in the pathogenesis of the idiopathic inflammatory bowel diseases (IBD), Crohn…”
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Motivations and concerns of patients with access to genetic testing for hereditary pancreatitis by Applebaum-Shapiro, S. E., Peters, J. A., O'Connell, J. A., Aston, C. E., Whitcomb, D. C.

“…Direct DNA testing is now available for hereditary pancreatitis (HP). This study aimed to identify the factors that motivated individuals to participate in…”
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A simplified six item checklist for screening for fragile X syndrome in the pediatric population by Giangreco, Cheryl A., Steele, Mark W., Aston, Christopher E., Cummins, James H., Wenger, Sharon L.

“…OBJECTIVE: In our general experience, about 2% of samples referred for fragile X testing showed positive results on Southern blot analysis. The aim of this…”
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Plasma Apolipoprotein A-I, Apolipoprotein B, and Lipoprotein(a) Concentrations in Normoglycemic Hispanics and Non-Hispanic Whites from the San Luis Valley, Colorado by Kamboh, M. llyas, Rewers, Marian, Aston, Christopher E., Hamman, Richard F.

“…Lower levels of plasma apolipoprotein (apo) A-I and higher levels of apoB, lipoprotein(a) (Lp(a)), and the ratio of apoB to apoA-I are considered to be…”
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The role of heterozygosity for CYP21 in the polycystic ovary syndrome by Witchel, S F, Aston, C E

“…The phenotypic heterogeneity recognized in congenital adrenal hyperplasia secondary to 21-hydroxylase deficiency appears to extend to 21hydroxylase (CYP21)…”
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