Search Results - "Asthana, Shreyasi"

IAPP in type II diabetes: Basic research on structure, molecular interactions, and disease mechanisms suggests potential intervention strategies by Asthana, Shreyasi, Mallick, Bibekanand, Alexandrescu, Andrei T., Jha, Suman

“…Islet amyloid polypeptide (a.k.a. IAPP, amylin) is a 37 amino acid hormone that has long been associated with the progression of type II diabetes mellitus…”
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Lactoferrin adsorption onto silver nanoparticle interface: Implications of corona on protein conformation, nanoparticle cytotoxicity and the formulation adjuvanticity by Nayak, Parth Sarathi, Borah, Sapna M., Gogoi, Himanshu, Asthana, Shreyasi, Bhatnagar, Rakesh, Jha, Anupam Nath, Jha, Suman

“…•BLf adsorption as corona reduces the cytotoxic propensity of AgNP.•BLf adsorption onto AgNP interface is predominantly enthalpically driven.•BLf in corona…”
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Insulin adsorption onto zinc oxide nanoparticle mediates conformational rearrangement into amyloid-prone structure with enhanced cytotoxic propensity by Asthana, Shreyasi, Hazarika, Zaved, Nayak, Parth Sarathi, Roy, Jyoti, Jha, Anupam Nath, Mallick, Bibekanand, Jha, Suman

“…Injection localized amyloidosis is one of the most prevalent disorders in type II diabetes mellitus (TIIDM) patients relying on insulin injections. Previous…”
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Detergent induced structural perturbations in peanut agglutinin: insights from spectroscopic and molecular dynamic simulation studies by Asthana, Shreyasi, Mohanty, Sonali, Kalra, Harshit, Karunanethy, Nandini, Kumar, Sujeet, Agrawal, Nikhil, Jha, Suman

“…The three dimensional structure of a protein is very important for its structure. Studies relating to protein structure have been numerous and the effect of…”
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Interaction with zinc oxide nanoparticle kinetically traps α-synuclein fibrillation into off-pathway non-toxic intermediates by Asthana, Shreyasi, Bhattacharyya, Dipita, Kumari, Swati, Nayak, Parth Sarathi, Saleem, Mohammed, Bhunia, Anirban, Jha, Suman

“…α-Synuclein is an intrinsically disordered amyloidogenic protein associated with Parkinson's disease (PD). The monomeric α-synuclein transition into amyloid…”
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The smaller heparin fragments bind non-specifically through the IAPP sequence: An in silico study by Asthana, Shreyasi, Sahu, Mousumi, Nayak, Parth Sarathi, Mallick, Bibekanand, Jha, Suman

“…The diminishing β-cell mass of pancreas in type II diabetes mellitus (TIIDM) is intricately linked with high fibrillation propensity of islet amyloid…”
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Biofabrication of silver nanoparticles using bacteria from mangrove swamp by Sharma, Manish, Nayak, Parth Sarthi, Asthana, Shreyasi, Mahapatra, Dipankar, Arakha, Manoranjan, Jha, Suman

“…The last decade has observed a rapid advancement in utilising biological system towards bioremediation of metal ions in the form of respective metal…”
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Chaotropes trigger conformational rearrangements differently in Concanavalin A by Asthana, Shreyasi, Bhutia, Sujit Kumar, Sahoo, Harekrushna, Jha, Suman

“…Concanavalin A (ConA) is a plant lectin having industrial and biological applications. Concanavalin A changes conformation upon exposure to different stress…”
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