Search Results - "Astashkin, Roman"

Molecular mechanism of light-driven sodium pumping by Kovalev, Kirill, Astashkin, Roman, Gushchin, Ivan, Orekhov, Philipp, Volkov, Dmytro, Zinovev, Egor, Marin, Egor, Rulev, Maksim, Alekseev, Alexey, Royant, Antoine, Carpentier, Philippe, Vaganova, Svetlana, Zabelskii, Dmitrii, Baeken, Christian, Sergeev, Ilya, Balandin, Taras, Bourenkov, Gleb, Carpena, Xavier, Boer, Roeland, Maliar, Nina, Borshchevskiy, Valentin, Büldt, Georg, Bamberg, Ernst, Gordeliy, Valentin

“…The light-driven sodium-pumping rhodopsin KR2 from Krokinobacter eikastus is the only non-proton cation active transporter with demonstrated potential for…”
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Structural insights into ion conduction by channelrhodopsin 2 by Volkov, Oleksandr, Kovalev, Kirill, Polovinkin, Vitaly, Borshchevskiy, Valentin, Bamann, Christian, Astashkin, Roman, Marin, Egor, Popov, Alexander, Balandin, Taras, Willbold, Dieter, Büldt, Georg, Bamberg, Ernst, Gordeliy, Valentin

“…The light-gated ion channel channelrhodopsin 2 (ChR2) from is a major optogenetic tool. Photon absorption starts a well-characterized photocycle, but the…”
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True-atomic-resolution insights into the structure and functional role of linear chains and low-barrier hydrogen bonds in proteins by Borshchevskiy, Valentin, Kovalev, Kirill, Round, Ekaterina, Efremov, Rouslan, Astashkin, Roman, Bourenkov, Gleb, Bratanov, Dmitry, Balandin, Taras, Chizhov, Igor, Baeken, Christian, Gushchin, Ivan, Kuzmin, Alexander, Alekseev, Alexey, Rogachev, Andrey, Willbold, Dieter, Engelhard, Martin, Bamberg, Ernst, Büldt, Georg, Gordeliy, Valentin

“…Hydrogen bonds are fundamental to the structure and function of biological macromolecules and have been explored in detail. The chains of hydrogen bonds (CHBs)…”
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Viral rhodopsins 1 are an unique family of light-gated cation channels by Zabelskii, Dmitrii, Alekseev, Alexey, Kovalev, Kirill, Rankovic, Vladan, Balandin, Taras, Soloviov, Dmytro, Bratanov, Dmitry, Savelyeva, Ekaterina, Podolyak, Elizaveta, Volkov, Dmytro, Vaganova, Svetlana, Astashkin, Roman, Chizhov, Igor, Yutin, Natalia, Rulev, Maksim, Popov, Alexander, Eria-Oliveira, Ana-Sofia, Rokitskaya, Tatiana, Mager, Thomas, Antonenko, Yuri, Rosselli, Riccardo, Armeev, Grigoriy, Shaitan, Konstantin, Vivaudou, Michel, Büldt, Georg, Rogachev, Andrey, Rodriguez-Valera, Francisco, Kirpichnikov, Mikhail, Moser, Tobias, Offenhäusser, Andreas, Willbold, Dieter, Koonin, Eugene, Bamberg, Ernst, Gordeliy, Valentin

“…Phytoplankton is the base of the marine food chain as well as oxygen and carbon cycles and thus plays a global role in climate and ecology. Nucleocytoplasmic…”
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Unique structure and function of viral rhodopsins by Bratanov, Dmitry, Kovalev, Kirill, Machtens, Jan-Philipp, Astashkin, Roman, Chizhov, Igor, Soloviov, Dmytro, Volkov, Dmytro, Polovinkin, Vitaly, Zabelskii, Dmitrii, Mager, Thomas, Gushchin, Ivan, Rokitskaya, Tatyana, Antonenko, Yuri, Alekseev, Alexey, Shevchenko, Vitaly, Yutin, Natalya, Rosselli, Riccardo, Baeken, Christian, Borshchevskiy, Valentin, Bourenkov, Gleb, Popov, Alexander, Balandin, Taras, Büldt, Georg, Manstein, Dietmar J., Rodriguez-Valera, Francisco, Fahlke, Christoph, Bamberg, Ernst, Koonin, Eugene, Gordeliy, Valentin

“…Recently, two groups of rhodopsin genes were identified in large double-stranded DNA viruses. The structure and function of viral rhodopsins are unknown. We…”
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Structure and mechanisms of sodium-pumping KR2 rhodopsin by Kovalev, Kirill, Polovinkin, Vitaly, Gushchin, Ivan, Alekseev, Alexey, Shevchenko, Vitaly, Borshchevskiy, Valentin, Astashkin, Roman, Balandin, Taras, Bratanov, Dmitry, Vaganova, Svetlana, Popov, Alexander, Chupin, Vladimir, Büldt, Georg, Bamberg, Ernst, Gordeliy, Valentin

“…Rhodopsins are the most universal biological light-energy transducers and abundant phototrophic mechanisms that evolved on Earth and have a remarkable…”
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Structure-based insights into evolution of rhodopsins by Zabelskii, Dmitrii, Dmitrieva, Natalia, Volkov, Oleksandr, Shevchenko, Vitaly, Kovalev, Kirill, Balandin, Taras, Soloviov, Dmytro, Astashkin, Roman, Zinovev, Egor, Alekseev, Alexey, Round, Ekaterina, Polovinkin, Vitaly, Chizhov, Igor, Rogachev, Andrey, Okhrimenko, Ivan, Borshchevskiy, Valentin, Chupin, Vladimir, Büldt, Georg, Yutin, Natalia, Bamberg, Ernst, Koonin, Eugene, Gordeliy, Valentin

“…Rhodopsins, most of which are proton pumps generating transmembrane electrochemical proton gradients, span all three domains of life, are abundant in the…”
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High-pressure crystallography shows noble gas intervention into protein-lipid interaction and suggests a model for anaesthetic action by Melnikov, Igor, Orekhov, Philipp, Rulev, Maksim, Kovalev, Kirill, Astashkin, Roman, Bratanov, Dmitriy, Ryzhykau, Yury, Balandin, Taras, Bukhdruker, Sergei, Okhrimenko, Ivan, Borshchevskiy, Valentin, Bourenkov, Gleb, Mueller-Dieckmann, Christoph, van der Linden, Peter, Carpentier, Philippe, Leonard, Gordon, Gordeliy, Valentin, Popov, Alexander

“…In this work we examine how small hydrophobic molecules such as inert gases interact with membrane proteins (MPs) at a molecular level. High pressure…”
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Crystal Structure of the N112A Mutant of the Light-Driven Sodium Pump KR2 by Maliar, Nina, Kovalev, Kirill, Baeken, Christian, Balandin, Taras, Astashkin, Roman, Rulev, Maksim, Alekseev, Alexey, Ilyinsky, Nikolay, Rogachev, Andrey, Chupin, Vladimir, Dolgikh, Dmitry, Kirpichnikov, Mikhail, Gordeliy, Valentin

“…The light-driven sodium pump KR2, found in 2013 in the marine bacteria Krokinobacter eikastus, serves as a model protein for the studies of the sodium-pumping…”
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Structure and dynamics of the SARS‐CoV‐2 envelope protein monomer by Kuzmin, Alexander, Orekhov, Philipp, Astashkin, Roman, Gordeliy, Valentin, Gushchin, Ivan

“…Coronaviruses, especially severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), present an ongoing threat to human wellbeing. Consequently, elucidation…”
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Insights into the mechanisms of light-oxygen-voltage domain color tuning from a set of high-resolution X-ray structures by Remeeva, Alina, Nazarenko, Vera V, Kovalev, Kirill, Goncharov, Ivan M, Yudenko, Anna, Astashkin, Roman, Gordeliy, Valentin, Gushchin, Ivan

“…Light-oxygen-voltage (LOV) domains are widespread photosensory modules that can be used in fluorescence microscopy, optogenetics and controlled production of…”
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Mechanisms of inward transmembrane proton translocation by Kovalev, Kirill, Tsybrov, Fedor, Alekseev, Alexey, Shevchenko, Vitaly, Soloviov, Dmytro, Siletsky, Sergey, Bourenkov, Gleb, Agthe, Michael, Nikolova, Marina, von Stetten, David, Astashkin, Roman, Bukhdruker, Sergey, Chizhov, Igor, Royant, Antoine, Kuzmin, Alexander, Gushchin, Ivan, Rosselli, Riccardo, Rodriguez-Valera, Francisco, Ilyinskiy, Nikolay, Rogachev, Andrey, Borshchevskiy, Valentin, Schneider, Thomas R., Bamberg, Ernst, Gordeliy, Valentin

“…Proton transport is indispensable for cell life. It is believed that molecular mechanisms of proton movement through different types of proton-conducting…”
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Structural insights into the effects of glycerol on ligand binding to cytochrome P450 by Bukhdruker, Sergey, Varaksa, Tatsiana, Orekhov, Philipp, Grabovec, Irina, Marin, Egor, Kapranov, Ivan, Kovalev, Kirill, Astashkin, Roman, Kaluzhskiy, Leonid, Ivanov, Alexis, Mishin, Alexey, Rogachev, Andrey, Gordeliy, Valentin, Gilep, Andrei, Strushkevich, Natallia, Borshchevskiy, Valentin

“…New antitubercular drugs are vital due to the spread of resistant strains. Carbethoxyhexyl imidazole (CHImi) inhibits cytochrome P450 CYP124, which is a…”
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Metabolic Fate of Human Immunoactive Sterols in Mycobacterium tuberculosis by Varaksa, Tatsiana, Bukhdruker, Sergey, Grabovec, Irina, Marin, Egor, Kavaleuski, Anton, Gusach, Anastasiia, Kovalev, Kirill, Maslov, Ivan, Luginina, Aleksandra, Zabelskii, Dmitrii, Astashkin, Roman, Shevtsov, Mikhail, Smolskaya, Sviatlana, Kavaleuskaya, Anna, Shabunya, Polina, Baranovsky, Alexander, Dolgopalets, Vladimir, Charnou, Yury, Savachka, Aleh, Litvinovskaya, Raisa, Hurski, Alaksiej, Shevchenko, Evgeny, Rogachev, Andrey, Mishin, Alexey, Gordeliy, Valentin, Gabrielian, Andrei, Hurt, Darrell E., Nikonenko, Boris, Majorov, Konstantin, Apt, Alexander, Rosenthal, Alex, Gilep, Andrei, Borshchevskiy, Valentin, Strushkevich, Natallia

“…[Display omitted] •Major human immune oxysterols are metabolized by at least four Mtb enzymes.•3βHSD is able to inactivate EBI2 agonists and…”
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