Search Results - "Assunta Lopedota, Angela"

Cyclodextrin-based supramolecular deep eutectic solvent (CycloDES): a vehicle for the delivery of poorly soluble drugs by Balenzano, Gennaro, Francesco Racaniello, Giuseppe, Arduino, Ilaria, Assunta Lopedota, Angela, Lopalco, Antonio, Laquintana, Valentino, Denora, Nunzio

“…[Display omitted] •Cyclodextrin-based deep eutectic solvents (CycloDES) could be exploit for poorly soluble drug solubilization.•The improved performance of…”
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Microfluidic development and biological evaluation of targeted therapy-loaded biomimetic nano system to improve the metastatic melanoma treatment by Arduino, Ilaria, Di Fonte, Roberta, Tiboni, Mattia, Porcelli, Letizia, Serratì, Simona, Fondaj, Dafina, Rafaschieri, Tania, Cutrignelli, Annalisa, Guida, Gabriella, Casettari, Luca, Azzariti, Amalia, Assunta Lopedota, Angela, Denora, Nunzio, Maria Iacobazzi, Rosa

“…Optimizing current therapies is among next steps in metastatic melanoma (MM) treatment landscape. The innovation of this study is the design of production…”
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Targeting human liver cancer cells with lactobionic acid-G(4)-PAMAM-FITC sorafenib loaded dendrimers by Iacobazzi, Rosa Maria, Porcelli, Letizia, Lopedota, Angela Assunta, Laquintana, Valentino, Lopalco, Antonio, Cutrignelli, Annalisa, Altamura, Emiliano, Di Fonte, Roberta, Azzariti, Amalia, Franco, Massimo, Denora, Nunzio

“…[Display omitted] Reported here is the synthesis and biological evaluation of the asialoglycoprotein receptor (ASGP-R) targeted fourth generation…”
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Exploring the Microfluidic Production of Biomimetic Hybrid Nanoparticles and Their Pharmaceutical Applications by Fondaj, Dafina, Arduino, Ilaria, Lopedota, Angela Assunta, Denora, Nunzio, Iacobazzi, Rosa Maria

“…Nanomedicines have made remarkable advances in recent years, addressing the limitations of traditional therapy and treatment methods. Due to their improved…”
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Chitosan and Anionic Solubility Enhancer Sulfobutylether-β-Cyclodextrin-Based Nanoparticles as Dexamethasone Ophthalmic Delivery System for Anti-Inflammatory Therapy by Racaniello, Giuseppe Francesco, Balenzano, Gennaro, Arduino, Ilaria, Iacobazzi, Rosa Maria, Lopalco, Antonio, Lopedota, Angela Assunta, Sigurdsson, Hakon Hrafn, Denora, Nunzio

“…Cataract surgery interventions are constantly increasing, particularly among adult and elderly patients. This type of surgery can lead to inflammatory states…”
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Digital Technologies Applied to Control the One-Step Process of Cannabis Olive Oil Preparations by Bongiorno, Paolo, Lopalco, Antonio, Casiraghi, Antonella, Spennacchio, Antonio, Pitruzzella, Alessandro, Lopedota, Angela Assunta, Minghetti, Paola, Denora, Nunzio

“…The reproducibility of an extemporaneous preparation is an essential condition for guaranteeing the quality, efficacy, and safety of the medicinal product…”
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Mucoadhesive Budesonide Solution for the Treatment of Pediatric Eosinophilic Esophagitis by Spennacchio, Antonio, Lopalco, Antonio, Racaniello, Giuseppe Francesco, Cutrignelli, Annalisa, la Forgia, Flavia Maria, Fontana, Sergio, Cristofori, Fernanda, Francavilla, Ruggiero, Lopedota, Angela Assunta, Denora, Nunzio

“…Eosinophilic Esophagitis is an antigen-mediated inflammatory disease characterized by thickening of the esophageal wall, leading to dysphagia, vomiting,…”
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β-Dystroglycan Restoration and Pathology Progression in the Dystrophic mdx Mouse: Outcome and Implication of a Clinically Oriented Study with a Novel Oral Dasatinib Formulation by Mantuano, Paola, Boccanegra, Brigida, Conte, Elena, De Bellis, Michela, Cirmi, Santa, Sanarica, Francesca, Cappellari, Ornella, Arduino, Ilaria, Cutrignelli, Annalisa, Lopedota, Angela Assunta, Mele, Antonietta, Denora, Nunzio, De Luca, Annamaria

“…ROS-activated cSrc tyrosine kinase (TK) promotes the degradation of β-dystroglycan (β-DG), a dystrophin-glycoprotein complex component, which may reinforce…”
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Hydroxy-Propil-β-Cyclodextrin Inclusion Complexes of two Biphenylnicotinamide Derivatives: Formulation and Anti-Proliferative Activity Evaluation in Pancreatic Cancer Cell Models by Iacobazzi, Rosa Maria, Cutrignelli, Annalisa, Stefanachi, Angela, Porcelli, Letizia, Lopedota, Angela Assunta, Di Fonte, Roberta, Lopalco, Antonio, Serratì, Simona, Laquintana, Valentino, Silvestris, Nicola, Franco, Massimo, Cellamare, Saverio, Leonetti, Francesco, Azzariti, Amalia, Denora, Nunzio

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies, with poor outcomes largely due to its unique microenvironment, which is…”
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Stability data of extemporaneous suspensions of hydroxychloroquine sulphate in oral liquid bases after tablet manipulation by Perrone, Mara, Laquintana, Valentino, Lopedota, Angela Assunta, Cutrignelli, Annalisa, Lopalco, Antonio, Franco, Massimo, Pepe, Antonio, Fontana, Sergio, Denora, Nunzio

“…Hydroxychloroquine is a well-known anti-malarial and anti-rheumatic drug that has garnered recently unprecedented attention as potential therapeutic agent…”
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TSPO Ligand-Methotrexate Prodrug Conjugates: Design, Synthesis, and Biological Evaluation by Laquintana, Valentino, Denora, Nunzio, Cutrignelli, Annalisa, Perrone, Mara, Iacobazzi, Rosa Maria, Annese, Cosimo, Lopalco, Antonio, Lopedota, Angela Assunta, Franco, Massimo

“…The 18-kDa translocator protein (TSPO) is a potential mitochondrial target for drug delivery to tumors overexpressing TSPO, including brain cancers, and…”
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The hydroxypropyl‐β‐cyclodextrin‐minoxidil inclusion complex improves the cardiovascular and proliferative adverse effects of minoxidil in male rats: Implications in the treatment of alopecia by Maqoud, Fatima, Zizzo, Nicola, Mele, Antonietta, Denora, Nunzio, Passantino, Giuseppe, Scala, Rosa, Cutrignelli, Annalisa, Tinelli, Antonella, Laquintana, Valentino, Forgia, Flavia, Fontana, Sergio, Franco, Massimo, Lopedota, Angela Assunta, Tricarico, Domenico

“…The efficacy of minoxidil (MXD) ethanolic solutions (1%‐5% w/v) in the treatment of androgenetic alopecia is limited by adverse reactions. The toxicological…”
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The Complexity of the Blood-Brain Barrier and the Concept of Age-Related Brain Targeting: Challenges and Potential of Novel Solid Lipid-Based Formulations by Sommonte, Federica, Arduino, Ilaria, Racaniello, Giuseppe Francesco, Lopalco, Antonio, Lopedota, Angela Assunta, Denora, Nunzio

“…Diseases that affect the Central Nervous System (CNS) are one of the most exciting challenges of recent years, as they are ubiquitous and affect all ages…”
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Direct cyclodextrin based powder extrusion 3D printing of budesonide loaded mini-tablets for the treatment of eosinophilic colitis in paediatric patients by Pistone, Monica, Racaniello, Giuseppe Francesco, Rizzi, Rosanna, Iacobazzi, Rosa Maria, Arduino, Ilaria, Lopalco, Antonio, Lopedota, Angela Assunta, Denora, Nunzio

“…[Display omitted] The purpose of this study was to combine direct powder extrusion (DPE) 3D printing and fluid bed coating techniques to create a budesonide…”
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PEGylated solid lipid nanoparticles for brain delivery of lipophilic kiteplatin Pt(IV) prodrugs: An in vitro study by Arduino, Ilaria, Depalo, Nicoletta, Re, Francesca, Dal Magro, Roberta, Panniello, Annamaria, Margiotta, Nicola, Fanizza, Elisabetta, Lopalco, Antonio, Laquintana, Valentino, Cutrignelli, Annalisa, Lopedota, Angela Assunta, Franco, Massimo, Denora, Nunzio

“…[Display omitted] Here, polyethylene glycol (PEG)-stabilized solid lipid nanoparticles (SLNs) containing Pt(IV) prodrugs derived from kiteplatin were designed…”
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Harnessing therapeutic deep eutectic solvents in self-emulsifying systems to improve CBD delivery by Balenzano, Gennaro, Racaniello, Giuseppe Francesco, Spennacchio, Antonio, Lopalco, Antonio, Iacobazzi, Rosa Maria, Lopedota, Angela Assunta, Laquintana, Valentino, Denora, Nunzio

“…[Display omitted] •A novel THEDES using CBD as a model drug was generated and characterized.•The hydrophobic nature of the obtained DES was adopted for the…”
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Multistimuli responsive microcapsules produced by the prilling/vibration technique for targeted colonic delivery of probiotics by D'Amico, Vita, Lopalco, Antonio, Iacobazzi, Rosa Maria, Vacca, Mirco, Siragusa, Sonya, De Angelis, Maria, Lopedota, Angela Assunta, Denora, Nunzio

“…[Display omitted] This study aimed to microencapsulate the probiotic strain Lactiplantibacillus plantarum 4S6R (basonym Lactobacillus plantarum) in both…”
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Microfluidic assembly of “Turtle-Like” shaped solid lipid nanoparticles for lysozyme delivery by Sommonte, Federica, Arduino, Ilaria, Iacobazzi, Rosa Maria, Tiboni, Mattia, Catalano, Federico, Marotta, Roberto, Di Francesco, Martina, Casettari, Luca, Decuzzi, Paolo, Lopedota, Angela Assunta, Denora, Nunzio

“…[Display omitted] After two decades of research in the field of nanomedicine, nanoscale delivery systems for biologicals are becoming clinically relevant…”
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Investigating the prilling/vibration technique to produce gastric-directed drug delivery systems for misoprostol by D'Amico, Vita, Denora, Nunzio, Ivone, Marianna, Iacobazzi, Rosa Maria, Laquintana, Valentino, Cutrignelli, Annalisa, Franco, Massimo, Barone, Michele, Lopalco, Antonio, Lopedota, Angela Assunta

“…[Display omitted] Prilling/vibration technique to produce oral microcapsules was explored to achieve local delivery of misoprostol (MIS), a prostaglandin E1…”
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Recent Advances in Nanodrug Delivery Systems Production, Efficacy, Safety, and Toxicity by Lopalco, Antonio, Iacobazzi, Rosa Maria, Lopedota, Angela Assunta, Denora, Nunzio

“…In the last three decades, the development of nanoparticles or nano-formulations as drug delivery systems has emerged as a promising tool to overcome the…”
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