Search Results - "Assumpção, Paulo P."
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Consumption of processed and ultra-processed foods by patients with stomach adenocarcinoma: a multicentric case–control study in the Amazon and southeast regions of Brazil
Published in Cancer causes & control (01-06-2022)“…Purpose There is limited information about the dietary habits associated with stomach adenocarcinoma in the Brazilian population, so our purpose is to analyze…”
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Physical activity and gastric cancer risk: a case-control study in the Amazon region of Brazil
Published in European journal of cancer prevention (01-11-2021)“…Gastric cancer is the fifth most common cancer worldwide. Investigations of lifestyle factors such as physical activity may identify risk patterns in this…”
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The Search for Cancer Biomarkers: Assessing the Distribution of INDEL Markers in Different Genetic Ancestries
Published in Current issues in molecular biology (19-05-2022)“…Cancer is a multifactorial group of diseases, being highly incident and one of the leading causes of death worldwide. In Brazil, there is a great variation in…”
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Association between INDELs in MicroRNAs and Susceptibility to Gastric Cancer in Amazonian Population
Published in Genes (24-12-2022)“…Gastric cancer (GC) is a multifactorial, complex, and aggressive disease with a prevalence of one million new cases and high global mortality. Factors such as…”
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Role of histone acetylation in gastric cancer: implications of dietetic compounds and clinical perspectives
Published in Epigenomics (01-02-2019)“…Histone modifications regulate the structural status of chromatin and thereby influence the transcriptional status of genes. These processes are controlled by…”
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HPV positive, wild type TP53, and p16 overexpression correlate with the absence of residual tumors after chemoradiotherapy in anal squamous cell carcinoma
Published in BMC gastroenterology (21-02-2018)“…Anal residual tumors are consensually identified within six months of chemoradiotherapy and represent a persistent lesion that may have prognostic value for…”
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Analysis of 12 variants in the development of gastric and colorectal cancers
Published in World journal of gastroenterology : WJG (28-12-2017)“…AIM To evaluate the relation between 12 polymorphisms and the development of gastric cancer(GC) and colorectal cancer(CRC).METHODS In this study,we included…”
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Estimating Asian Contribution to the Brazilian Population: A New Application of a Validated Set of 61 Ancestry Informative Markers
Published in G3 : genes - genomes - genetics (01-11-2018)“…Estimates of different ancestral proportions in admixed populations are very important in population genetics studies, especially for the detection of…”
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Gastric Cancer Cell Lines Have Different MYC-Regulated Expression Patterns but Share a Common Core of Altered Genes
Published in Canadian journal of gastroenterology & hepatology (01-01-2018)“…MYC is an oncogene responsible for excessive cell growth in cancer, enabling transcriptional activation of genes involved in cell cycle regulation, metabolism,…”
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Analysis of 8q24.21 miRNA cluster expression and copy number variation in gastric cancer
Published in Future medicinal chemistry (01-05-2019)“… To analyze gene expression and copy number of five miRNAs ( , , , and ) localized in this chromosome region in gastric cancer (GC). 65 paired neoplastic and…”
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Association between Polymorphism of Genes IL-1A , NFKB1 , PAR1 , TP53, and UCP2 and Susceptibility to Non-Small Cell Lung Cancer in the Brazilian Amazon
Published in Genes (10-02-2023)“…Non-small cell lung cancer (NSCLC) accounts for the vast majority of cases of lung neoplasms. It is formed in multiple stages, with interactions between…”
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UGT1A1 Gene Polymorphism Contributes as a Risk Factor for Lung Cancer: A Pilot Study with Patients from the Amazon
Published in Genes (11-03-2022)“…Lung cancer is one of the most frequent neoplasms in the world. Because it is a complex disease, its formation occurs in several stages, stemming from…”
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Exome Evaluation of Autism-Associated Genes in Amazon American Populations
Published in Genes (18-02-2022)“…Autism spectrum disorder is a neurodevelopmental disorder, affecting one in 160 children worldwide. The causes of autism are still poorly understood, but…”
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Current Perspectives on Circulating Tumor DNA, Precision Medicine, and Personalized Clinical Management of Cancer
Published in Molecular cancer research (01-04-2020)“…Circulating tumor DNA (ctDNA) has recently emerged as a minimally invasive "liquid biopsy" tool in precision medicine. ctDNA-genomic DNA fragments that are…”
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Polymorphisms in the CYP2A6 and ABCC4 genes are associated with a protective effect on chronic myeloid leukemia in the Brazilian Amazon population
Published in Molecular genetics & genomic medicine (01-07-2021)“…Background Susceptibility to Chronic Myeloid Leukemia (CML) may be modulated by genetic variables. However, the majority of previous investigations have…”
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The Role of SLC22A1 and Genomic Ancestry on Toxicity during Treatment in Children with Acute Lymphoblastic Leukemia of the Amazon Region
Published in Genes (29-03-2022)“…In Brazil, Acute lymphoid leukemia (ALL) is the leading cause of cancer deaths in children and adolescents. Treatment toxicity is one of the reasons for…”
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Amerindian genetic ancestry and INDEL polymorphisms associated with susceptibility of childhood B-cell Leukemia in an admixed population from the Brazilian Amazon
Published in Leukemia research (01-11-2015)“…Highlights • The INDEL polymorphism in CASP8 is associated with decreasing chances of developing B-cell ALL. • The INDEL polymorphism in CYP19A1 is associated…”
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Identification of Genomic Variants Associated with the Risk of Acute Lymphoblastic Leukemia in Native Americans from Brazilian Amazonia
Published in Journal of personalized medicine (25-05-2022)“…A number of genomic variants related to native American ancestry may be associated with an increased risk of developing Acute Lymphoblastic Leukemia (ALL),…”
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Association of the rs4646994 in ACE gene with susceptibility to tuberculosis in a region of the Brazilian Amazon
Published in Translational medicine communications (01-01-2022)“…Tuberculosis (TB) is an infectious disease caused by the bacterium and represents an important global public health issue. Single-nucleotide polymorphisms and…”
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Interrelationship between TP53 gene deletion, protein expression and chromosome 17 aneusomy in gastric adenocarcinoma
Published in BMC gastroenterology (20-07-2009)“…This study evaluates the existence of numerical alterations of chromosome 17 and TP53 gene deletion in gastric adenocarcinoma. The p53 protein expression was…”
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