Search Results - "Assmann, Julian C"

In vivo deuterium magnetic resonance imaging of xenografted tumors following systemic administration of deuterated water by Brender, Jeffrey R., Assmann, Julian C., Farthing, Don E., Saito, Keita, Kishimoto, Shun, Warrick, Kathrynne A., Maglakelidze, Natella, Larus, Terri L., Merkle, Hellmut, Gress, Ronald E., Krishna, Murali C., Buxbaum, Nataliya P.

“…In vivo deuterated water ( 2 H 2 O) labeling leads to deuterium ( 2 H) incorporation into biomolecules of proliferating cells and provides the basis for its…”
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Brain endothelial TAK1 and NEMO safeguard the neurovascular unit by Ridder, Dirk A, Wenzel, Jan, Müller, Kristin, Töllner, Kathrin, Tong, Xin-Kang, Assmann, Julian C, Stroobants, Stijn, Weber, Tobias, Niturad, Cristina, Fischer, Lisanne, Lembrich, Beate, Wolburg, Hartwig, Grand'Maison, Marilyn, Papadopoulos, Panayiota, Korpos, Eva, Truchetet, Francois, Rades, Dirk, Sorokin, Lydia M, Schmidt-Supprian, Marc, Bedell, Barry J, Pasparakis, Manolis, Balschun, Detlef, D'Hooge, Rudi, Löscher, Wolfgang, Hamel, Edith, Schwaninger, Markus

“…Inactivating mutations of the NF-κB essential modulator (NEMO), a key component of NF-κB signaling, cause the genetic disease incontinentia pigmenti (IP). This…”
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The Immunometabolomic Interface Receptor Hydroxycarboxylic Acid Receptor 2 Mediates the Therapeutic Effects of Dimethyl Fumarate in Autoantibody-Induced Skin Inflammation by Wannick, Melanie, Assmann, Julian C, Vielhauer, Jakob F, Offermanns, Stefan, Zillikens, Detlef, Sadik, Christian D, Schwaninger, Markus

“…The drug dimethyl fumarate (DMF) is in clinical use for the treatment of psoriasis and multiple sclerosis. In addition, it has recently been demonstrated to…”
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Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE by Chen, Hui, Assmann, Julian C, Krenz, Antje, Rahman, Mahbubur, Grimm, Myriam, Karsten, Christian M, Köhl, Jörg, Offermanns, Stefan, Wettschureck, Nina, Schwaninger, Markus

“…Taken orally, the drug dimethyl fumarate (DMF) has been shown to improve functional outcomes for patients with MS; however, it is unclear how DMF mediates a…”
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Oral Dimethyl Fumarate Targets HCA2-Expressing Skin Cells in the Imiquimod Mouse Model by Suhrkamp, Ina, Morrison, Peter J., Assmann, Julian C., Schwaninger, Markus, Wettschureck, Nina, Mrowietz, Ulrich

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Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice by Wenzel, Jan, Hansen, Cathrin E., Bettoni, Carla, Vogt, Miriam A., Lembrich, Beate, Natsagdorj, Rentsenkhand, Huber, Gianna, Brands, Josefine, Schmidt, Kjestine, Assmann, Julian C., Stölting, Ines, Saar, Kathrin, Sedlacik, Jan, Fiehler, Jens, Ludewig, Peter, Wegmann, Michael, Feller, Nina, Richter, Marius, Müller-Fielitz, Helge, Walther, Thomas, König, Gabriele M., Kostenis, Evi, Raasch, Walter, Hübner, Norbert, Gass, Peter, Offermanns, Stefan, de Wit, Cor, Wagner, Carsten A., Schwaninger, Markus

“…Carbon dioxide (CO₂), the major product of metabolism, has a strong impact on cerebral blood vessels, a phenomenon known as cerebrovascular reactivity. Several…”
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A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS by Johann, Lisa, Soldati, Sasha, Müller, Kristin, Lampe, Josephine, Marini, Federico, Klein, Matthias, Schramm, Eva, Ries, Nathalie, Schelmbauer, Carsten, Palagi, Ilaria, Karram, Khalad, Assmann, Julian C, Khan, Mahtab A, Wenzel, Jan, Schmidt, Mirko Hh, Körbelin, Jakob, Schlüter, Dirk, van Loo, Geert, Bopp, Tobias, Engelhardt, Britta, Schwaninger, Markus, Waisman, Ari

“…A20 is a ubiquitin-modifying protein that negatively regulates NF-κB signaling. Mutations in A20/TNFAIP3 are associated with a variety of autoimmune diseases,…”
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Genetic manipulation of brain endothelial cells in vivo by Assmann, Julian C., Körbelin, Jakob, Schwaninger, Markus

“…Brain endothelial cells take center stage of the blood–brain barrier. They maintain homeostasis in the central nervous system (CNS) and are involved in the…”
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Cerebral angiogenesis ameliorates pathological disorders in Nemo-deficient mice with small-vessel disease by Jiang, Yun, Müller, Kristin, Khan, Mahtab A., Assmann, Julian C., Lampe, Josephine, Kilau, Knut, Richter, Marius, Kleint, Maximilian, Ridder, Dirk A, Hübner, Norbert, Schmidt-Supprian, Marc, Wenzel, Jan, Schwaninger, Markus

“…Cerebral small-vessel diseases (SVDs) often follow a progressive course. Little is known about the function of angiogenesis, which potentially induces…”
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Glycolytic metabolism of pathogenic T cells enables early detection of GVHD by 13C-MRI by Assmann, Julian C., Farthing, Don E., Saito, Keita, Maglakelidze, Natella, Oliver, Brittany, Warrick, Kathrynne A., Sourbier, Carole, Ricketts, Christopher J., Meyer, Thomas J., Pavletic, Steven Z., Linehan, W. Marston, Krishna, Murali C., Gress, Ronald E., Buxbaum, Nataliya P.

“…Graft-versus-host disease (GVHD) is a prominent barrier to allogeneic hematopoietic stem cell transplantation (AHSCT). Definitive diagnosis of GVHD is…”
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Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE by Chen, Hui, Assmann, Julian C, Krenz, Antje, Rahman, Mahbubur, Grimm, Myriam, Karsten, Christian M, Kohl, Jorg, Offermanns, Stefan, Wettschureck, Nina, Schwaninger, Markus

“…Taken orally, the drug dimethyl fumarate (DMF) has been shown to improve functional outcomes for patients with MS; however, it is unclear how DMF mediates a…”
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Dimethyl Fumarate Ameliorates Disease Severity in a Mouse Model of Chronic Graft-Versus-Host Disease by Assmann, Julian C., Warrick, Kathrynne, Johns, Christopher, Farthing, Don E., Gress, Ronald E., Buxbaum, Nataliya P.

“…Chronic graft-versus host disease (cGvHD) is a major complication of allogeneic hematopoietic stem cell transplantation. Standard treatment mainly consists of…”
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