Search Results - "Assaf, Khaleel"

The Chaotropic Effect as an Assembly Motif in Chemistry by Assaf, Khaleel I., Nau, Werner M.

“…Following up on scattered reports on interactions of conventional chaotropic ions (for example, I−, SCN−, ClO4−) with macrocyclic host molecules, biomolecules,…”
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Applications of Cucurbiturils in Medicinal Chemistry and Chemical Biology by Das, Debapratim, Assaf, Khaleel I., Nau, Werner M.

“…The supramolecular chemistry of cucurbit[ n ]urils (CB n ) has been rapidly developing to encompass diverse medicinal applications, including drug formulation…”
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Boron clusters as broadband membrane carriers by Barba-Bon, Andrea, Salluce, Giulia, Lostalé-Seijo, Irene, Assaf, Khaleel. I., Hennig, Andreas, Montenegro, Javier, Nau, Werner M.

“…The membrane translocation of hydrophilic substances constitutes a challenge for their application as therapeutic compounds and labelling probes 1 – 4 . To…”
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Water Structure Recovery in Chaotropic Anion Recognition: High-Affinity Binding of Dodecaborate Clusters to [gamma]-Cyclodextrin by Assaf, Khaleel I, Ural, Merve S, Pan, Fangfang, Georgiev, Tony, Simova, Svetlana, Rissanen, Kari, Gabel, Detlef, Nau, Werner M

“…Dodecaborate anions of the type B12X122- and B12X11Y2- (X=H, Cl, Br, I and Y=OH, SH, NH3+, NR3+) form strong (Ka up to 106Lmol-1, for B12Br122-) inclusion…”
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Water Structure Recovery in Chaotropic Anion Recognition: High-Affinity Binding of Dodecaborate Clusters to γ-Cyclodextrin by Assaf, Khaleel I., Ural, Merve S., Pan, Fangfang, Georgiev, Tony, Simova, Svetlana, Rissanen, Kari, Gabel, Detlef, Nau, Werner M.

“…Dodecaborate anions of the type B12X122− and B12X11Y2− (X=H, Cl, Br, I and Y=OH, SH, NH3+, NR3+) form strong (Ka up to 106 L mol−1, for B12Br122−) inclusion…”
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Dispersion Interactions in Condensed Phases and inside Molecular Containers by Assaf, Khaleel I, Nau, Werner M

“…ConspectusThe past decade has seen significant progress in the understanding and appreciation of the importance of London dispersion interactions (LDIs) in…”
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Nanomolar Binding of Steroids to Cucurbit[n]urils: Selectivity and Applications by Lazar, Alexandra I, Biedermann, Frank, Mustafina, Kamila R, Assaf, Khaleel I, Hennig, Andreas, Nau, Werner M

“…Cucurbit­[n]­urils (CBn, n = 7, 8) serve as artificial receptors for steroids (21 tested), including the hormones testosterone and estradiol as well as…”
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Supramolecular Catalysis of a Catalysis-Resistant Diels–Alder Reaction: Almost Theoretical Acceleration of Cyclopentadiene Dimerization inside Cucurbit[7]uril by Tehrani, Foad N, Assaf, Khaleel I, Hein, Robert, Jensen, Casper M. E, Nugent, Thomas C, Nau, Werner M

“…In contrast to Diels–Alder reactions involving heteroatom-containing substrates, the endo dimerization of cyclopentadiene responds only very weakly to changes…”
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A Fluorescein-Substituted Perbrominated Dodecaborate Cluster as an Anchor Dye for Large Macrocyclic Hosts and Its Application in Indicator Displacement Assays by Zhang, Jinling, Gabel, Detlef, Assaf, Khaleel I., Nau, Werner M.

“…Perhalogenated boron clusters derived from B12Br12 2–, a superchaotropic dianion with a globular icosahedral shape, serve as inorganic cavity binders for…”
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High-affinity host-guest chemistry of large-ring cyclodextrins by Assaf, Khaleel I, Gabel, Detlef, Zimmermann, Wolfgang, Nau, Werner M

“…The host-guest chemistry of large-ring cyclodextrins (LRCDs) has been largely unexplored due to the lack of suitable guest molecules that bind with significant…”
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A Selective Cucurbit[8]uril‐Peptide Beacon Ensemble for the Ratiometric Fluorescence Detection of Peptides by Maity, Debabrata, Assaf, Khaleel I., Sicking, Wilhelm, Hirschhäuser, Christoph, Nau, Werner M., Schmuck, Carsten

“…A convenient supramolecular strategy for constructing a ratiometric fluorescent chemosensing ensemble, consisting of a macrocyclic host (cucurbit[8]uril…”
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High-Affinity Binding of Metallacarborane Cobalt Bis(dicarbollide) Anions to Cyclodextrins and Application to Membrane Translocation by Assaf, Khaleel I, Begaj, Barbara, Frank, Angelina, Nilam, Mohamed, Mougharbel, Ali S, Kortz, Ulrich, Nekvinda, Jan, Grüner, Bohumír, Gabel, Detlef, Nau, Werner M

“…Metallacarboranes are a class of inorganic boron clusters that have recently been recognized as biologically active compounds. Herein, we report on the…”
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Deep Inside Cucurbiturils: Physical Properties and Volumes of their Inner Cavity Determine the Hydrophobic Driving Force for Host-Guest Complexation by Nau, Werner M., Florea, Mara, Assaf, Khaleel I.

“…Cucurbit[n]urils (CBn) bind guest molecules through a combination of electrostatic interactions with the carbonyl rims and hydrophobic interactions with the…”
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Ratiometric DNA sensing with a host-guest FRET pair by Zhang, Shuai, Assaf, Khaleel I, Huang, Chusen, Hennig, Andreas, Nau, Werner M

“…A supramolecular host-guest FRET pair based on a carboxyfluorescein-labelled cucurbit[7]uril (CB7-CF, as acceptor) and the fluorescent dye…”
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Preparation, characterization, and biological activity study of thymoquinone-cucurbit[7]uril inclusion complex by Alrawashdeh, Lubna, Assaf, Khaleel I, Alshaer, Walhan, Odeh, Fadwa, Bani-Atta, Suhair A

“…In this study, the formation of a host-guest inclusion complex between cucurbit[7]uril (CB[7]) and thymoquinone (TQ) was investigated in aqueous solution. The…”
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Dodecaborate-Functionalized Anchor Dyes for Cyclodextrin-Based Indicator Displacement Applications by Assaf, Khaleel I, Suckova, Olga, Al Danaf, Nader, von Glasenapp, Victoria, Gabel, Detlef, Nau, Werner M

“…A new type of water-soluble anchor dyes, that is, dyes which carry an auxiliary unit for strong binding to macrocyclic host molecules, has been synthesized. It…”
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Preferential binding of unsaturated hydrocarbons in aryl-bisimidazolium·cucurbit[8]uril complexes furbishes evidence for small-molecule π-π interactions by Barrow, Steven J, Assaf, Khaleel I, Palma, Aniello, Nau, Werner M, Scherman, Oren A

“…Whilst cucurbit[ n ]urils (CB n ) have been utilized in gas encapsulation, only the smaller CB n ( n = 5 and 6) have utility given their small cavity size. In…”
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HYDROPHOBE Challenge: A Joint Experimental and Computational Study on the Host–Guest Binding of Hydrocarbons to Cucurbiturils, Allowing Explicit Evaluation of Guest Hydration Free-Energy Contributions by Assaf, Khaleel I, Florea, Mara, Antony, Jens, Henriksen, Niel M, Yin, Jian, Hansen, Andreas, Qu, Zheng-wang, Sure, Rebecca, Klapstein, Dieter, Gilson, Michael K, Grimme, Stefan, Nau, Werner M

“…The host–guest complexation of hydrocarbons (22 guest molecules) with cucurbit[7]­uril was investigated in aqueous solution using the indicator displacement…”
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Halogen Bonding inside a Molecular Container by El-Sheshtawy, Hamdy S, Bassil, Bassem S, Assaf, Khaleel I, Kortz, Ulrich, Nau, Werner M

“…The synthetic macrocycle cucurbit[6]­uril forms host–guest inclusion complexes with molecular dibromine and diiodine. As evidenced by their crystal structures,…”
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Selective Detection of Nitroexplosives Using Molecular Recognition within Self-Assembled Plasmonic Nanojunctions by Chio, Weng-I Katherine, Peveler, William J, Assaf, Khaleel I, Moorthy, Suresh, Nau, Werner M, Parkin, Ivan P, Olivo, Malini, Lee, Tung-Chun

“…We demonstrate that the reproducibility of sensors for nitroaromatics based on surface-enhanced Raman spectroscopy (SERS) can be significantly improved via a…”
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