Search Results - "Assa’ad, Amal H."

Effect of Varying Doses of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Exposure Among Patients With Peanut Sensitivity: A Randomized Clinical Trial by Sampson, Hugh A, Shreffler, Wayne G, Yang, William H, Sussman, Gordon L, Brown-Whitehorn, Terri F, Nadeau, Kari C, Cheema, Amarjit S, Leonard, Stephanie A, Pongracic, Jacqueline A, Sauvage-Delebarre, Christine, Assa’ad, Amal H, de Blay, Frederic, Bird, J. Andrew, Tilles, Stephen A, Boralevi, Franck, Bourrier, Thierry, Hébert, Jacques, Green, Todd D, Gerth van Wijk, Roy, Knulst, André C, Kanny, Gisèle, Schneider, Lynda C, Kowalski, Marek L, Dupont, Christophe

“…IMPORTANCE: Epicutaneous immunotherapy may have potential for treating peanut allergy but has been assessed only in preclinical and early human trials…”
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Focus on the Patient with Food Allergy by Assa’ad, Amal H.

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Work Group report: Oral food challenge testing by Nowak-Węgrzyn, Anna, MD, Assa'ad, Amal H., MD, Bahna, Sami L., MD, DrPH, Bock, S. Allan, MD, Sicherer, Scott H., MD, Teuber, Suzanne S., MD

“…Oral food challenges are procedures conducted by allergists/immunologists to make an accurate diagnosis of immediate, and occasionally delayed, adverse…”
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Biologics in eosinophilic esophagitis by Zhang, Simin, Assa’ad, Amal H.

“…Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the oesophagus whose incidence is on the rise. Despite maximal use of guideline-based…”
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Primary Prevention of Allergic Disease Through Nutritional Interventions by Fleischer, David M., MD, Spergel, Jonathan M., MD, PhD, Assa'ad, Amal H., MD, Pongracic, Jacqueline A., MD

“…With the rising prevalence of atopic disease, primary prevention may play a role in reducing its burden, especially in high-risk infants. With this in mind,…”
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Defects of B-cell terminal differentiation in patients with type-1 Kabuki syndrome by Lindsley, Andrew W., MD, PhD, Saal, Howard M., MD, Burrow, Thomas A., MD, Hopkin, Robert J., MD, Shchelochkov, Oleg, MD, Khandelwal, Pooja, MD, Xie, Changchun, PhD, Bleesing, Jack, MD, PhD, Filipovich, Lisa, MD, Risma, Kimberly, MD, PhD, Assa'ad, Amal H., MD, Roehrs, Phillip A., MD, Bernstein, Jonathan A., MD

“…Background Kabuki syndrome (KS) is a complex multisystem developmental disorder associated with mutation of genes encoding histone-modifying proteins. In…”
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Racial Differences in Food Allergy Phenotype and Health Care Utilization among US Children by Mahdavinia, Mahboobeh, MD, PhD, Fox, Susan R., PA, Smith, Bridget M., PhD, James, Christine, MD, Palmisano, Erica L., MD, Mohammed, Aisha, MD, Zahid, Zeeshan, MD, Assa'ad, Amal H., MD, Tobin, Mary C., MD, Gupta, Ruchi S., MD, MPH

“…Background Food allergy (FA) is a prevalent condition in the United States, but little is known about its phenotypes in racial minority groups. Objective The…”
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Persistent, refractory, and biphasic anaphylaxis: A multidisciplinary Delphi study by Dribin, Timothy E., Sampson, Hugh A., Camargo, Carlos A., Brousseau, David C., Spergel, Jonathan M., Neuman, Mark I., Shaker, Marcus, Campbell, Ronna L., Michelson, Kenneth A., Rudders, Susan A., Assa’ad, Amal H., Risma, Kimberly A., Castells, Mariana, Schneider, Lynda C., Wang, Julie, Lee, Juhee, Mistry, Rakesh D., Vyles, David, Vaughn, Lisa M., Schumacher, Daniel J., Witry, John K., Viswanathan, Shiv, Page, Erica M., Schnadower, David

“…The use of inconsistent definitions for anaphylaxis outcomes limits our understanding of the natural history and epidemiology of anaphylaxis, hindering…”
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Efficacy and Safety of AR101 in Oral Immunotherapy for Peanut Allergy: Results of ARC001, a Randomized, Double-Blind, Placebo-Controlled Phase 2 Clinical Trial by Bird, J. Andrew, Spergel, Jonathan M., Jones, Stacie M., Rachid, Rima, Assa'ad, Amal H., Wang, Julie, Leonard, Stephanie A., Laubach, Susan S., Kim, Edwin H., Vickery, Brian P., Davis, Benjamin P., Heimall, Jennifer, Cianferoni, Antonella, MacGinnitie, Andrew J., Crestani, Elena, Burks, A. Wesley

“…Peanut oral immunotherapy, using a variety of approaches, has been previously shown to induce desensitization in peanut-allergic subjects, but no products have…”
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Monoclonal Antibodies for Treatment of Eosinophilic Esophagitis by Eskian, Mahsa, Khorasanizadeh, MirHojjat, Assa’ad, Amal H., Rezaei, Nima

“…Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus affecting both children and adults, with debilitating and progressive…”
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A Randomized, Double-Blind, Placebo-Controlled Trial of Fluticasone Propionate for Pediatric Eosinophilic Esophagitis by Konikoff, Michael R., Noel, Richard J., Blanchard, Carine, Kirby, Cassie, Jameson, Sean C., Buckmeier, Bridget K., Akers, Rachel, Cohen, Mitchell B., Collins, Margaret H., Assa’ad, Amal H., Aceves, Seema S., Putnam, Philip E., Rothenberg, Marc E.

“…Background & Aims: Eosinophilic esophagitis is an increasingly recognized disorder with distinctive endoscopic, histologic, and allergic features. Although…”
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Associations of Food Allergy-Related Dietary Knowledge, Attitudes, and Behaviors Among Caregivers of Black and White Children With Food Allergy by Vincent, Eileen, Bilaver, Lucy A., Fierstein, Jamie L., Thivalapill, Neil, Pappalardo, Andrea A., Coleman, Amaziah, Robinson, Adam, Sharma, Hemant P., Brewer, Audrey, Assa’ad, Amal H., Jiang, Jialing, Hultquist, Haley W., Kulkarni, Ashwin J., Choi, Johnathan, Mahdavinia, Mahboobeh, Pongracic, Jacqueline, Tobin, Mary C., Warren, Christopher, Gupta, Ruchi S.

“…The increasing prevalence of pediatric food allergy (FA) in the United States has disproportionately affected non-Hispanic Black youth. However, racial and…”
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Anaphylaxis knowledge gaps and future research priorities: A consensus report by Dribin, Timothy E., Schnadower, David, Wang, Julie, Camargo, Carlos A., Michelson, Kenneth A., Shaker, Marcus, Rudders, Susan A., Vyles, David, Golden, David B.K., Spergel, Jonathan M., Campbell, Ronna L., Neuman, Mark I., Capucilli, Peter S., Pistiner, Michael, Castells, Mariana, Lee, Juhee, Brousseau, David C., Schneider, Lynda C., Assa’ad, Amal H., Risma, Kimberly A., Mistry, Rakesh D., Campbell, Dianne E., Worm, Margitta, Turner, Paul J., Witry, John K., Zhang, Yin, Sobolewski, Brad, Sampson, Hugh A.

“…Despite a better understanding of the epidemiology, pathogenesis, and management of patients with anaphylaxis, there remain knowledge gaps. Enumerating and…”
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Breakthroughs in understanding and treating eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERs Symposium at the 2022 American Academy of Allergy, Asthma & Immunology Meeting by Chehade, Mirna, Wright, Benjamin L, Atkins, Dan, Aceves, Seema S, Ackerman, Steven J, Assa'ad, Amal H, Bauer, Maureen, Collins, Margaret H, Commins, Scott P, Davis, Carla M, Dellon, Evan S, Doerfler, Bethan, Gleich, Gerald J, Gupta, Sandeep K, Hill, David A, Jensen, Elizabeth T, Katzka, David, Kliewer, Kara, Kodroff, Ellyn, Kottyan, Leah C, Kyle, Shay, Muir, Amanda B, Pesek, Robert D, Peterson, Kathryn, Shreffler, Wayne G, Spergel, Jonathan M, Strobel, Mary Jo, Wechsler, Joshua, Zimmermann, Nives, Furuta, Glenn T, Rothenberg, Marc E

“…The Consortium of Eosinophilic Gastrointestinal Diseases and The International Gastrointestinal Eosinophil Researchers organized a day-long symposium at the…”
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OIT-BRAVE questionnaire: Development and clinical implementation of a screening instrument for patient-reported difficulties during oral immunotherapy by Underwood, Brynne, Mills, Christa, Devonshire, Ashley L., Andorf, Sandra, Assa’ad, Amal H., Ramsey, Rachelle, Schwartz, Justin T.

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Severity grading system for acute allergic reactions: A multidisciplinary Delphi study by Dribin, Timothy E., Schnadower, David, Spergel, Jonathan M., Campbell, Ronna L., Shaker, Marcus, Neuman, Mark I., Michelson, Kenneth A., Capucilli, Peter S., Camargo, Carlos A., Brousseau, David C., Rudders, Susan A., Assa’ad, Amal H., Risma, Kimberly A., Castells, Mariana, Schneider, Lynda C., Wang, Julie, Lee, Juhee, Mistry, Rakesh D., Vyles, David, Pistiner, Michael, Witry, John K., Zhang, Yin, Sampson, Hugh A.

“…There is no widely adopted severity grading system for acute allergic reactions, including anaphylactic and nonanaphylactic reactions, thus limiting the…”
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Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis by Blanchard, Carine, Wang, Ning, Stringer, Keith F, Mishra, Anil, Fulkerson, Patricia C, Abonia, J Pablo, Jameson, Sean C, Kirby, Cassie, Konikoff, Michael R, Collins, Margaret H, Cohen, Mitchell B, Akers, Rachel, Hogan, Simon P, Assa'ad, Amal H, Putnam, Philip E, Aronow, Bruce J, Rothenberg, Marc E

“…Eosinophilic esophagitis (EE) is an emerging disorder with a poorly understood pathogenesis. In order to define disease mechanisms, we took an empirical…”
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Anti–IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels by Stein, Miguel L., MD, Villanueva, Joyce M., BS, Buckmeier, Bridget K., BA, Yamada, Yoshiyuki, MD, Filipovich, Alexandra H., MD, Assa'ad, Amal H., MD, Rothenberg, Marc E., MD, PhD

“…Background Anti–IL-5 might be a useful therapeutic agent for eosinophilic disorders, yet its immunologic consequences have not been well characterized…”
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Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis by Sherrill, Joseph D., PhD, Gao, Pei-Song, MD, PhD, Stucke, Emily M., BA, Blanchard, Carine, PhD, Collins, Margaret H., MD, Putnam, Phil E., MD, Franciosi, James P., MD, Kushner, Jonathan P., MD, Abonia, J. Pablo, MD, Assa'ad, Amal H., MD, Kovacic, Melinda Butsch, PhD, Biagini Myers, Jocelyn M., PhD, Bochner, Bruce S., MD, He, Hua, MS, Hershey, Gurjit Khurana, MD, PhD, Martin, Lisa J., PhD, Rothenberg, Marc E., MD, PhD

“…Background The genetic cause of eosinophilic esophagitis (EE) has been largely unexplored until a recent genome-wide association study identified a disease…”
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Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines update - III - Cow's milk allergens and mechanisms triggering immune activation by Jensen, Sebastian A, Fiocchi, Alessandro, Baars, Ton, Jordakieva, Galateja, Nowak-Wegrzyn, Anna, Pali-Schöll, Isabella, Passanisi, Stefano, Pranger, Christina L, Roth-Walter, Franziska, Takkinen, Kristiina, Assa'ad, Amal H, Venter, Carina, Jensen-Jarolim, Erika

“…BackgroundThe immunopathogenesis of cow's milk protein allergy (CMPA) is based on different mechanisms related to immune recognition of protein epitopes, which…”
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