Search Results - "Asrorov Akmal M."
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Advances on Delivery of Cytotoxic Enzymes as Anticancer Agents
Published in Molecules (Basel, Switzerland) (01-06-2022)“…Cancer is one of the most serious human diseases, causing millions of deaths worldwide annually, and, therefore, it is one of the most investigated research…”
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Most accurate mutations in SARS-CoV-2 genomes identified in Uzbek patients show novel amino acid changes
Published in Frontiers in medicine (31-05-2024)“…The rapid changes in the coronavirus genomes created new strains after the first variation was found in Wuhan in 2019. SARS-CoV-2 genotypes should periodically…”
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Improvement of callogenesis and somatic embryogenesis by selecting optimal hormonal balance in Sarnav and Desiree potato varieties
Published in Agriculture (01-04-2023)“…Callus formation and somatic embryogenesis in potato varieties are effective ways to obtain an entire plant from a single cell. The implementation of…”
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Chemical composition and biological activity of seed oil of amaranth varieties
Published in Nova Biotechnologica et Chimica (01-07-2018)“…The work is devoted to study of seed oil composition of amaranth varieties: Kharkov, Lera, Andijan and Helios, acclimatized in Uzbekistan. We demonstrated the…”
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Magnetism-mediated targeting hyperthermia-immunotherapy in “cold” tumor with CSF1R inhibitor
Published in Theranostics (01-01-2021)“…Background: Immunotherapy has profoundly changed the landscape of cancer management and represented the most significant breakthrough. Yet, it is a formidable…”
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Mannosylated engineered trichosanthin-legumain protein vaccine hydrogel for breast cancer immunotherapy
Published in International journal of biological macromolecules (31-12-2022)“…The development of cancer vaccines based on tumor-associated antigens is hurdled by lack of an efficient adjuvant and insufficient efficacy. To improve the…”
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Cell penetrating peptides: Highlighting points in cancer therapy
Published in Drug development research (01-09-2023)“…Cell-penetrating peptides (CPPs), first identified in HIV a few decades ago, deserved great attention in the last two decades; especially to support the…”
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Toad venom bufadienolides and bufotoxins: An updated review
Published in Drug development research (01-08-2023)“…Bufadienolides, naturally found in toad venoms having steroid‐like structures, reveal antiproliferative effects at low doses. However, their application as…”
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Advances on Tumor-Targeting Delivery of Cytotoxic Proteins
Published in ACS pharmacology & translational science (14-02-2020)“…Great attention has been paid to cytotoxic proteins (e.g., ribosome-inactivating proteins, RIPs) possessing high anticancer activities; unlike small drugs,…”
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Deformable liposomal codelivery of vorinostat and simvastatin promotes antitumor responses through remodeling tumor microenvironment
Published in Biomaterials science (15-12-2020)“…The tumor microenvironment (TME) and its major component tumor-associated macrophages (TAM) play a pivotal role in the development of non-small cell lung…”
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Food Protein‐Derived Zinc‐Binding Peptides: Isolation, Purification, and Biological Aspects
Published in Peptide science (Hoboken, N.J.) (25-07-2024)“…ABSTRACT Zinc is the second most valuable microelement after iron, according to its abundance in the human body. Supplementation of this metal is not…”
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Albumin is a reliable drug-delivering molecule: Highlighting points in cancer therapy
Published in Medicine in drug discovery (01-06-2024)“…[Display omitted] As the most abundant protein in the blood, albumin binds and transports hydrophilic, hydrophobic, and lipophilic molecules required for the…”
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Coronavirus spike protein-based vaccines. Vaccine delivery systems
Published in Medicine in drug discovery (01-12-2024)“…Spike protein has been established as one of the molecules playing a pivotal role in coronavirus infection. On its bases, several vaccines have been developed,…”
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Changes in Soluble Protein Profile in Cotton Leaves Indicate Rubisco Damage after Treatment with Sumi-Alpha Insecticide
Published in Agriculture (Warsaw) (01-04-2020)“…The cotton plant suffers from many pests and due to its economic importance, the use of efficient but ecologically friendly pesticides is highly desirable. The…”
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Characterization of a novel lipase from Pseudomonas aeruginosa
Published in Nova biotechnologica et chimica (01-06-2019)“…Lipases cleaving oils into fatty acids and glycerol are of great interest for the use in increasing the efficiency of fuels. In this work, a novel lipase from…”
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Low abundant bovine colostrum proteins in combination with amaranth oil reveal topical analgesic activity
Published in Nova biotechnologica et chimica (03-06-2022)“…Colostrum is an arsenal of proteins and peptides required at the earliest stage of a newborn development. Proteins involved in all biological processes of an…”
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Comparative chemical composition of seeds of amaranth varieties introduced in Uzbekistan
Published in Nova biotechnologica et chimica (30-06-2020)“…Amaranth is one of ancient cultured plants possessing valuable food quality that is still important in modern agriculture. In this work, we studied the seed…”
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