Search Results - "Asprino, Paula F"

Commensal oral microbiota impacts ulcerative oral mucositis clinical course in allogeneic stem cell transplant recipients by Bruno, Julia S., Heidrich, Vitor, Knebel, Franciele H., de Molla, Vinícius Campos, Parahyba, Claudia Joffily, Miranda-Silva, Wanessa, Asprino, Paula F., Tucunduva, Luciana, Rocha, Vanderson, Novis, Yana, Arrais-Rodrigues, Celso, Camargo, Anamaria A., Fregnani, Eduardo R.

“…Oral mucositis (OM) is a complex acute cytotoxicity of antineoplastic treatment that affects 40–85% of patients undergoing hematopoietic stem-cell…”
Get full text

Set7 deletion attenuates isoproterenol-induced cardiac fibrosis and delays cardiac dysfunction by Lunardon, Guilherme, de Oliveira Silva, Tábatha, Lino, Caroline A, Lu, Yao Wei, Miranda, Juliane B, Asprino, Paula F, de Almeida Silva, Amanda, Nepomuceno, Gabrielle T, Irigoyen, Maria Cláudia Costa, Carneiro-Ramos, Marcela S, Takano, Ana Paula C, Martinho, Herculano da Silva, Barreto-Chaves, Maria Luiza M, Wang, Da-Zhi, Diniz, Gabriela P

“…Cardiovascular diseases are the main cause of death worldwide. Recent studies have revealed the influence of histone-modifying enzymes in cardiac remodeling…”
Get more information

The Clinical and Molecular Profile of Lung Cancer Patients Harboring the TP53 R337H Germline Variant in a Brazilian Cancer Center: The Possible Mechanism of Carcinogenesis by Lopes, Carlos D. H., Antonacio, Fernanda F., Moraes, Priscila M. G., Asprino, Paula F., Galante, Pedro A. F., Jardim, Denis L., de Macedo, Mariana P., Sandoval, Renata L., Katz, Artur, de Castro, Gilberto, Achatz, Maria Isabel

“…In southern and southeastern Brazil, the TP53 founder variant c.1010G>A (R337H) has been previously documented with a prevalence of 0.3% within the general…”
Get full text

Dental Biofilm Microbiota Dysbiosis Is Associated With the Risk of Acute Graft- Versus -Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation by Heidrich, Vitor, Bruno, Julia S, Knebel, Franciele H, de Molla, Vinícius C, Miranda-Silva, Wanessa, Asprino, Paula F, Tucunduva, Luciana, Rocha, Vanderson, Novis, Yana, Arrais-Rodrigues, Celso, Fregnani, Eduardo R, Camargo, Anamaria A

“…Acute graft- -host disease (aGVHD) is one of the major causes of death after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Recently, aGVHD…”
Get full text

Choice of 16S Ribosomal RNA Primers Impacts Male Urinary Microbiota Profiling by Heidrich, Vitor, Inoue, Lilian T, Asprino, Paula F, Bettoni, Fabiana, Mariotti, Antonio C H, Bastos, Diogo A, Jardim, Denis L F, Arap, Marco A, Camargo, Anamaria A

“…Accessibility to next-generation sequencing (NGS) technologies has enabled the profiling of microbial communities living in distinct habitats. 16S ribosomal…”
Get full text

Longitudinal analysis at three oral sites links oral microbiota to clinical outcomes in allogeneic hematopoietic stem-cell transplant by Heidrich, Vitor, Knebel, Franciele H, Bruno, Julia S, de Molla, Vinícius C, Miranda-Silva, Wanessa, Asprino, Paula F, Tucunduva, Luciana, Rocha, Vanderson, Novis, Yana, Fregnani, Eduardo R, Arrais-Rodrigues, Celso, Camargo, Anamaria A

“…The oral cavity is the ultimate doorway for microbes entering the human body. We analyzed oral microbiota dynamics in allogeneic hematopoietic stem-cell…”
Get full text

Monoallelic deleterious MUTYH germline variants as a driver for tumorigenesis by Barreiro, Rodrigo Araujo Sequeira, Sabbaga, Jorge, Rossi, Benedito M, Achatz, Maria Isabel W, Bettoni, Fabiana, Camargo, Anamaria A, Asprino, Paula F, Galante, Pedro

“…MUTYH encodes a glycosylase involved in the base excision repair of DNA. Biallelic pathogenic germline variants in MUTYH cause an autosomal recessive condition…”
Get full text

Suspected Germline TP53 Variants and Clonal Hematopoiesis of Indeterminate Potential: Lessons Learned From a Molecular Tumor Board by Xavier, Camila B, Link, Rudinei, Abreu, Leonília, Bettoni, Fabiana, Marson, Fabiane, Galante, Pedro A F, Masotti, Cibele, Amano, Mariane T, de Molla, Vinicius, Camargo, Anamaria A, Asprino, Paula F, Sabbaga, Jorge

“…Abstract Objective Li-Fraumeni syndrome (LFS) is a pan-cancer predisposition syndrome caused by germline pathogenic variants in the gene TP53. The…”
Get full text

Fibroblast growth factor 2 restrains Ras-driven proliferation of malignant cells by triggering RhoA-mediated senescence by Costa, Erico T, Forti, Fábio L, Matos, Tatiana G F, Dermargos, Alexandre, Nakano, Fábio, Salotti, Jacqueline, Rocha, Kátia M, Asprino, Paula F, Yoshihara, Celina K, Koga, Marianna M, Armelin, Hugo A

“…Fibroblast growth factor 2 (FGF2) is considered to be a bona fide oncogenic factor, although results from our group and others call this into question. Here,…”
Get full text

Urinary microbiota is associated to clinicopathological features in benign prostatic hyperplasia by Mariotti, Antonio C H, Heidrich, Vitor, Inoue, Lilian T, Coser, Elisangela M, Dos Santos, Ernande X, Dos Santos, Hugo D B, Rocha, Carolina B T, Asprino, Paula F, Bettoni, Fabiana, Bastos, Diogo A, Jardim, Denis L F, Camargo, Anamaria A, Arap, Marco A

“…The urinary microbiota of patients with benign prostatic hyperplasia (BPH) has been associated with lower urinary tract symptoms (LUTS), however, little is…”
Get full text

The bladder microbiota is not significantly altered by intravesical BCG therapy by Heidrich, Vitor, Mariotti, Antonio C H, Inoue, Lilian T, Coser, Elisangela M, Dos Santos, Ernande X, Dos Santos, Hugo D B, Asprino, Paula F, Bettoni, Fabiana, Costa, Guilherme A P, Bastos, Diogo A, Jardim, Denis L, Arap, Marco A, Camargo, Anamaria A

“…Bladder microbiota dysbiosis has been associated with several urological disorders. However, dysbiosis markers in bladder cancer have not been identified and…”
Get full text

Comprehensive evaluation of the effectiveness of gene expression signatures to predict complete response to neoadjuvant chemoradiotherapy and guide surgical intervention in rectal cancer by Lopes-Ramos, Camila, Koyama, Fernanda C, Habr-Gama, Angelita, Salim, Anna Christina M, Bettoni, Fabiana, Asprino, Paula F, França, Gustavo S, Gama-Rodrigues, Joaquim, Parmigiani, Raphael B, Perez, Rodrigo O, Galante, Pedro A.F, Camargo, Anamaria A

“…Neoadjuvant chemoradiotherapy (nCRT) may lead to complete tumor regression in rectal cancer patients. Prediction of complete response to nCRT may allow a…”
Get full text

Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy by Donnard, Elisa, Asprino, Paula F, Correa, Bruna R, Bettoni, Fabiana, Koyama, Fernanda C, Navarro, Fabio C P, Perez, Rodrigo O, Mariadason, John, Sieber, Oliver M, Strausberg, Robert L, Simpson, Andrew J G, Jardim, Denis L F, Reis, Luiz Fernando L, Parmigiani, Raphael B, Galante, Pedro A F, Camargo, Anamaria A

“…We carried out a mutational analysis of 3,594 genes coding for cell surface proteins (Surfaceome) in 23 colorectal cancer cell lines, searching for new altered…”
Get full text

NDRG4 promoter hypermethylation is a mechanistic biomarker associated with metastatic progression in breast cancer patients by Jandrey, Elisa H. F., Moura, Ricardo P., Andrade, Luciana N. S., Machado, Camila L., Campesato, Luiz Felipe, Leite, Katia Ramos M., Inoue, Lilian T., Asprino, Paula F., da Silva, Ana Paula M., de Barros, Alfredo Carlos S. D., Carvalho, Andre, de Lima, Vladmir C., Carraro, Dirce M., Brentani, Helena P., da Cunha, Isabela W., Soares, Fernando A., Parmigiani, Raphael B., Chammas, Roger, Camargo, Anamaria A., Costa, Érico T.

“…The risk of developing metastatic disease in breast cancer patients is traditionally predictable based on the number of positive axillary lymph nodes,…”
Get full text

The Clinical and Molecular Profile of Lung Cancer Patients Harboring the ITP53/I R337H Germline Variant in a Brazilian Cancer Center: The Possible Mechanism of Carcinogenesis by Lopes, Carlos D. H, Antonacio, Fernanda F, Moraes, Priscila M. G, Asprino, Paula F, Galante, Pedro A. F, Jardim, Denis L, de Macedo, Mariana P, Sandoval, Renata L, Katz, Artur, de Castro, Gilberto, Achatz, Maria Isabel

“…In southern and southeastern Brazil, the TP53 founder variant c.1010G>A (R337H) has been previously documented with a prevalence of 0.3% within the general…”
Get full text

ORAL MICROBIOME INFLUENCES THE CLINICAL COURSE OF ORAL MUCOSITIS IN ALLOGENEIC HSCT PATIENTS by Bruno, Julia S., Heidrich, Vitor, Knebel, Franciele H., De Molla, Vinícius C., Miranda-Silva, Wanessa, Asprino, Paula F., Tucunduva, Luciana, Rocha, Vanderson, Novis, Yana, Arrais-Rodrigues, Celso, Camargo, Anamaria A., Fregnani, Eduardo R.

“…Oral mucositis (OM) is a complex acute cytotoxicity of antineoplastic treatment that affects 40% to 85% of patients undergoing hematopoietic stem cell…”
Get full text

Abstract 05: Genetic heterogeneity in rectal cancer - Identification of subpopulations of tumor cells resistant to neoadjuvant CRT by Bettoni, Fabiana, Donnard, Elisa R., Correa, Bruna R. S., Asprino, Paula F., Koyama, Fernanda C., Felício, Natália M., Hessel, Bruna H., Galante, Pedro A. F., Camargo, Anamaria A., Habr-Gama, Angelita, Perez, Rodrigo O.

“…Abstract One of the benefits of neoadjuvant chemotherapy and radiation therapy (CRT) for the management of rectal cancer is tumor downstaging that can…”
Get full text

Abstract A133: Genetic heterogeneity in rectal cancer: Identification of subpopulations of tumor cells resistant to neoadjuvant CRT by Bettoni, Fabiana, Donnard, Elisa R., Correa, Bruna R. S., Asprino, Paula F., Koyama, Fernanda C., Felício, Natália M., Hessel, Bruna H., Galante, Pedro A. F., Camargo, Anamaria A., Habr-Gama, Angelita, Perez, Rodrigo O.

“…Abstract One of the benefits of neoadjuvant chemotherapy and radiation therapy (CRT) for the management of rectal cancer is tumor downstaging that can…”
Get full text