Search Results - "Aspelund, Thor"

Co-regulatory networks of human serum proteins link genetics to disease by Emilsson, Valur, Ilkov, Marjan, Lamb, John R, Finkel, Nancy, Gudmundsson, Elias F, Pitts, Rebecca, Hoover, Heather, Gudmundsdottir, Valborg, Horman, Shane R, Aspelund, Thor, Shu, Le, Trifonov, Vladimir, Sigurdsson, Sigurdur, Manolescu, Andrei, Zhu, Jun, Olafsson, Örn, Jakobsdottir, Johanna, Lesley, Scott A, To, Jeremy, Zhang, Jia, Harris, Tamara B, Launer, Lenore J, Zhang, Bin, Eiriksdottir, Gudny, Yang, Xia, Orth, Anthony P, Jennings, Lori L, Gudnason, Vilmundur

“…Proteins circulating in the blood are critical for age-related disease processes; however, the serum proteome has remained largely unexplored. To this end,…”
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A genome-wide association study of serum proteins reveals shared loci with common diseases by Gudjonsson, Alexander, Gudmundsdottir, Valborg, Axelsson, Gisli T., Gudmundsson, Elias F., Jonsson, Brynjolfur G., Launer, Lenore J., Lamb, John R., Jennings, Lori L., Aspelund, Thor, Emilsson, Valur, Gudnason, Vilmundur

“…With the growing number of genetic association studies, the genotype-phenotype atlas has become increasingly more complex, yet the functional consequences of…”
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Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility - Reykjavik Study by Mitchell, Gary F., van Buchem, Mark A., Sigurdsson, Sigurdur, Gotal, John D., Jonsdottir, Maria K., Kjartansson, Ólafur, Garcia, Melissa, Aspelund, Thor, Harris, Tamara B., Gudnason, Vilmundur, Launer, Lenore J.

“…Aortic stiffness increases with age and vascular risk factor exposure and is associated with increased risk for structural and functional abnormalities in the…”
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Coding and regulatory variants are associated with serum protein levels and disease by Emilsson, Valur, Gudmundsdottir, Valborg, Gudjonsson, Alexander, Jonmundsson, Thorarinn, Jonsson, Brynjolfur G., Karim, Mohd A., Ilkov, Marjan, Staley, James R., Gudmundsson, Elias F., Launer, Lenore J., Lindeman, Jan H., Morton, Nicholas M., Aspelund, Thor, Lamb, John R., Jennings, Lori L., Gudnason, Vilmundur

“…Circulating proteins can be used to diagnose and predict disease-related outcomes. A deep serum proteome survey recently revealed close associations between…”
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Increased respiratory morbidity associated with exposure to a mature volcanic plume from a large Icelandic fissure eruption by Carlsen, Hanne Krage, Ilyinskaya, Evgenia, Baxter, Peter J., Schmidt, Anja, Thorsteinsson, Throstur, Pfeffer, Melissa Anne, Barsotti, Sara, Dominici, Francesca, Finnbjornsdottir, Ragnhildur Gudrun, Jóhannsson, Thorsteinn, Aspelund, Thor, Gislason, Thorarinn, Valdimarsdóttir, Unnur, Briem, Haraldur, Gudnason, Thorolfur

“…The 2014–15 Holuhraun eruption in Iceland was the largest fissure eruption in over 200 years, emitting prodigious amounts of gas and particulate matter into…”
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Prevalence and prognosis of ischaemic and non-ischaemic myocardial fibrosis in older adults by Shanbhag, Sujata M, Greve, Anders M, Aspelund, Thor, Schelbert, Erik B, Cao, J Jane, Danielsen, Ragnar, þorgeirsson, Guðmundur, Sigurðsson, Sigurður, Eiríksdóttir, Guðný, Harris, Tamara B, Launer, Lenore J, Guðnason, Vilmundur, Arai, Andrew E

“…Abstract Aims Non-ischaemic cardiomyopathies (NICM) can cause heart failure and death. Cardiac magnetic resonance (CMR) detects myocardial scar/fibrosis…”
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Improved brain perfusion after electrical cardioversion of atrial fibrillation by Gardarsdottir, Marianna, Sigurdsson, Sigurdur, Aspelund, Thor, Gardarsdottir, Valdis Anna, Forsberg, Lars, Gudnason, Vilmundur, Arnar, David O

“…Abstract Aims Atrial fibrillation (AF) has been associated with reduced brain volume, cognitive impairment, and reduced cerebral blood flow. The causes of…”
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Preeclampsia and academic performance in children: A nationwide study from Iceland by Sverrisson, Fridgeir A, Bateman, Brian T, Aspelund, Thor, Skulason, Sigurgrimur, Zoega, Helga

“…Hypertensive disorders complicate up to 10% of pregnancies. Evidence suggests a potential association between maternal hypertensive disorders during pregnancy,…”
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Heterogeneity in white blood cells has potential to confound DNA methylation measurements by Adalsteinsson, Bjorn T, Gudnason, Haukur, Aspelund, Thor, Harris, Tamara B, Launer, Lenore J, Eiriksdottir, Gudny, Smith, Albert V, Gudnason, Vilmundur

“…Epigenetic studies are commonly conducted on DNA from tissue samples. However, tissues are ensembles of cells that may each have their own epigenetic profile,…”
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Definition of excessive daytime sleepiness in the general population: Feeling sleepy relates better to sleep‐related symptoms and quality of life than the Epworth Sleepiness Scale score. Results from an epidemiological study by Thorarinsdottir, Elin H., Bjornsdottir, Erla, Benediktsdottir, Bryndis, Janson, Christer, Gislason, Thorarinn, Aspelund, Thor, Kuna, Samuel T., Pack, Allan I., Arnardottir, Erna S.

“…Many different subjective tools are being used to measure excessive daytime sleepiness (EDS) but the most widely used is the Epworth Sleepiness Scale (ESS)…”
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Prevalence and Prognosis of Unrecognized Myocardial Infarction Determined by Cardiac Magnetic Resonance in Older Adults by Schelbert, Erik B, Cao, Jie J, Sigurdsson, Sigurdur, Aspelund, Thor, Kellman, Peter, Aletras, Anthony H, Dyke, Christopher K, Thorgeirsson, Gudmundur, Eiriksdottir, Gudny, Launer, Lenore J, Gudnason, Vilmundur, Harris, Tamara B, Arai, Andrew E

“…CONTEXT Unrecognized myocardial infarction (MI) is prognostically important. Electrocardiography (ECG) has limited sensitivity for detecting unrecognized MI…”
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Trends in the incidence and prevalence of atrial fibrillation in Iceland and future projections by Stefansdottir, Hrafnhildur, Aspelund, Thor, Gudnason, Vilmundur, Arnar, David O.

“…Aims Data are scarce on the epidemiology of atrial fibrillation (AF) in Europe. The aim of this study was to examine recent trends in the incidence and…”
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Prevalence and determinants of carotid plaque in the cross-sectional REFINE-Reykjavik study by Sturlaugsdottir, Ran, Aspelund, Thor, Bjornsdottir, Gudlaug, Sigurdsson, Sigurdur, Thorsson, Bolli, Eiriksdottir, Gudny, Gudnason, Vilmundur

“…ObjectiveCarotid plaque and intima-media thickness are non-invasive arterial markers that are used as surrogate end points for cardiovascular disease. The aim…”
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Mediation analysis of aortic stiffness and renal microvascular function by Woodard, Todd, Sigurdsson, Sigurdur, Gotal, John D, Torjesen, Alyssa A, Inker, Lesley A, Aspelund, Thor, Eiriksdottir, Gudny, Gudnason, Vilmundur, Harris, Tamara B, Launer, Lenore J, Levey, Andrew S, Mitchell, Gary F

“…Aortic stiffening, assessed by carotid-femoral pulse wave velocity, is associated with CKD. Transmission of excessive flow pulsatility into the low-impedance…”
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Hemostatic factors and risk of coronary heart disease in general populations: new prospective study and updated meta-analyses by Willeit, Peter, Thompson, Alexander, Aspelund, Thor, Rumley, Ann, Eiriksdottir, Gudny, Lowe, Gordon, Gudnason, Vilmundur, Di Angelantonio, Emanuele

“…Activation of blood coagulation and fibrinolysis may be associated with increased risk of coronary heart disease. We aimed to assess associations of…”
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Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals by Casanova, Ramon, Varma, Sudhir, Simpson, Brittany, Kim, Min, An, Yang, Saldana, Santiago, Riveros, Carlos, Moscato, Pablo, Griswold, Michael, Sonntag, Denise, Wahrheit, Judith, Klavins, Kristaps, Jonsson, Palmi V, Eiriksdottir, Gudny, Aspelund, Thor, Launer, Lenore J, Gudnason, Vilmundur, Legido Quigley, Cristina, Thambisetty, Madhav

“…Abstract Introduction Recently, quantitative metabolomics identified a panel of 10 plasma lipids that were highly predictive of conversion to Alzheimer's…”
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Fractures and survival in multiple myeloma: results from a population-based study by Thorsteinsdottir, Sigrun, Gislason, Gauti, Aspelund, Thor, Sverrisdottir, Ingigerdur, Landgren, Ola, Turesson, Ingemar, Björkholm, Magnus, Kristinsson, Sigurður Y

“…Multiple myeloma causes lytic bone lesions and fractures. The impact of fractures on multiple myeloma (MM) survival is unclear. The aim of this study was to…”
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Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium by Alonso, Alvaro, Krijthe, Bouwe P, Aspelund, Thor, Stepas, Katherine A, Pencina, Michael J, Moser, Carlee B, Sinner, Moritz F, Sotoodehnia, Nona, Fontes, João D, Janssens, A Cecile J W, Kronmal, Richard A, Magnani, Jared W, Witteman, Jacqueline C, Chamberlain, Alanna M, Lubitz, Steven A, Schnabel, Renate B, Agarwal, Sunil K, McManus, David D, Ellinor, Patrick T, Larson, Martin G, Burke, Gregory L, Launer, Lenore J, Hofman, Albert, Levy, Daniel, Gottdiener, John S, Kääb, Stefan, Couper, David, Harris, Tamara B, Soliman, Elsayed Z, Stricker, Bruno H C, Gudnason, Vilmundur, Heckbert, Susan R, Benjamin, Emelia J

“…Tools for the prediction of atrial fibrillation (AF) may identify high-risk individuals more likely to benefit from preventive interventions and serve as a…”
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Adverse childhood experiences and resilience among adult women: A population-based study by Daníelsdóttir, Hilda Björk, Aspelund, Thor, Thordardottir, Edda Bjork, Fall, Katja, Fang, Fang, Tómasson, Gunnar, Rúnarsdóttir, Harpa, Yang, Qian, Choi, Karmel W, Kennedy, Beatrice, Halldorsdottir, Thorhildur, Lu, Donghao, Song, Huan, Jakobsdóttir, Jóhanna, Hauksdóttir, Arna, Valdimarsdóttir, Unnur Anna

“…Adverse childhood experiences (ACEs) have consistently been associated with elevated risk of multiple adverse health outcomes, yet their contribution to coping…”
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Cross-sectional study of early postpartum pelvic floor dysfunction and related bother in primiparous women 6–10 weeks postpartum by Sigurdardottir, Thorgerdur, Bø, Kari, Steingrimsdottir, Thora, Halldorsson, Thorhallur I., Aspelund, Thor, Geirsson, Reynir T.

“…Introduction and hypothesis To study the prevalence of pelvic floor dysfunction and related bother in primiparous women 6–10 weeks postpartum, comparing…”
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