Search Results - "Asoh, Yoshinori"
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Permeation characteristics of a hydrophilic basic compound across a bio-mimetic artificial membrane
Published in International journal of pharmaceutics (04-05-2004)“…In the present study, the permeation characteristics of a hydrophilic basic compound (HBC) in a bio-mimetic parallel artificial membrane permeability assay…”
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The stability and degradation pathway of recombinant human parathyroid hormone : Deamidation of asparaginyl residue and peptide bond cleavage at aspartyl and asparaginyl residues
Published in Pharmaceutical research (01-12-1997)“…The stability of recombinant human parathyroid hormone (rhPTH) was examined under acidic to alkaline conditions; its degradation pathways were elucidated from…”
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Probing the Unfolding and Refolding Processes of Carbonic Anhydrase 2 Using Electrospray Ionization Mass Spectrometry Combined with pH Jump
Published in Analytical chemistry (Washington) (01-11-2007)“…A novel method for proving the time course of the unfolding and refolding processes of metalloprotein bovine carbonic anhydrase 2 (CA2) is demonstrated using…”
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Measurements of diffusion coefficient of CF2 radical in DC pulsed CF4 discharge plasma
Published in Japanese journal of applied physics (01-10-1993)Get full text
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Folding analysis of hormonal polypeptide calcitonins and the oxidized calcitonins using electrospray ionization mass spectrometry combined with H/D exchange
Published in Journal of the American Society for Mass Spectrometry (01-11-2004)“…Conformational change of calcitonins has been examined by measuring the rate of hydrogen/deuterium (H/D) exchange in amino acids. Time dependent m/z shift…”
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DIFFERENTIAL TIME COURSE OF INDUCTION OF 1α,25-DIHYDROXYVITAMIN D 3-24-HYDROXYLASE mRNA EXPRESSION IN RATS BY 1α,25-DIHYDROXYVITAMIN D 3 AND ITS ANALOGS
Published in Life sciences (1973) (26-12-1997)“…In order to investigate the in vivo mechanisms of target gene activation by vitamin D 3 analogs, we compared the effects of two vitamin D 3 analogs,…”
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Oxidation of recombinant human parathyroid hormone : effect of oxidized position on the biological activity
Published in Pharmaceutical research (01-12-1995)“…To determine the oxidation products of recombinant human parathyroid hormone (rhPTH) treated with H2O2, the amino acid residue oxidized, and the biological…”
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Carrier-Mediated Hepatobiliary Transport of a Novel Antifolate,N-[4-[(2,4-Diamminopteridine-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl-L-Homoglutamic Acid, in Rats
Published in Drug metabolism and disposition (01-04-2001)“…The hepatic uptake and biliary excretion of a novel methotrexate derivative, N- [4-[(2,4-diamminopteridine-6-yl)methyl]-3,4-dihydro-2 H…”
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Kinetic study of methionine oxidation in human parathyroid hormone
Published in Analytica chimica acta (05-06-1998)“…Human parathyroid hormone (hPTH) has two methionine (Met) residues at positions 8 and 18. These are oxidized to Met sulfoxide in the presence of an oxidant…”
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Peptide mapping of recombinant human parathyroid hormone by enzymatic digestion and subsequent fast-atom bombardment mass spectrometry
Published in Rapid communications in mass spectrometry (1995)“…Peptide maps of recombinant human parathyroid hormone (rhPTH) were determined by both trypsin and V-8 protease digestion with subsequent fast-atom bombardment…”
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Measurements of diffusion coefficient of CF sub(2) radical in DC pulsed CF sub(4) discharge plasma
Published in Japanese Journal of Applied Physics, Part 2: Letters (01-01-1993)“…Laser-induced fluorescence has been used to measure the CF sub(2) radical ground-state densities after extinction of DC pulsed CF sub(4) discharge plasma. From…”
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Measurements of Diffusion Coefficient of CF 2 Radical in DC Pulsed CF 4 Discharge Plasma
Published in Japanese Journal of Applied Physics (01-10-1993)“…Laser-induced fluorescence has been used to measure the CF 2 radical ground-state densities after extinction of DC pulsed CF 4 discharge plasma. From the…”
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Determination of 22-oxacalcitriol, a new analog of 1α,25-dihydroxyvitamin D 3, in human serum by liquid chromatography–mass spectrometry
Published in Journal of chromatography. Biomedical applications (20-03-1998)“…A sensitive and specific liquid chromatographic–mass spectrometric assay has been developed for the determination of 22-oxacalcitriol (OCT), which is a new…”
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