Search Results - "Asogwa, Nnaemeka Tobechukwu"
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Antidiabetic activity of avocado seeds (Persea americana Mill.) in diabetic rats via activation of PI3K/AKT signaling pathway
Published in Scientific reports (21-02-2022)“…The treatment of diabetes involves the use of herbal plants, attracting interest in their cost-effectiveness and efficacy. An aqueous extract of Persea…”
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Hippocampal Degeneration and Behavioral Impairment During Alzheimer-Like Pathogenesis Involves Glutamate Excitotoxicity
Published in Journal of molecular neuroscience (01-06-2021)“…The hallmarks of Alzheimer’s disease (AD) pathology include senile plaques accumulation and neurofibrillary tangles, which is thought to underlie synaptic…”
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Antidiabetic Activity of Elephant Grass (Cenchrus Purpureus (Schumach.) Morrone) via Activation of PI3K/AkT Signaling Pathway, Oxidative Stress Inhibition, and Apoptosis in Wistar Rats
Published in Frontiers in pharmacology (02-03-2022)“…The management of diabetes over the years has involved the use of herbal plants, which are now attracting interest. We assessed the antidiabetic properties of…”
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Theobroma cacao fortified-feed ameliorates potassium bromate-induced oxidative damage in male Wistar rat
Published in Toxicology reports (01-01-2023)“…Some therapeutic and beneficial health properties of the Theobroma cacao leaf have been documented. This study evaluated the ameliorative effect of Theobroma…”
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Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats
Published in BMC complementary and alternative medicine (26-08-2022)“…Background Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal…”
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Profiling the antidiabetic potential of GC-MS compounds identified from the methanolic extract of Spilanthes filicaulis : experimental and computational insight
Published in Journal of biomolecular structure & dynamics (12-12-2023)“…This study examines the nutritional composition, phytochemical profiling, and antioxidant, antidiabetic, and anti-inflammatory potential of a methanolic…”
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Amino acid profile, physicochemical and sensory properties of noodles produced from wheat-Bambara protein isolate
Published in Measurement. Food (01-02-2022)“…•Noodles can be prepared from wheat-Bambara protein isolate.•Wheat-Bambara protein isolate noodles have good cooking quality.•Wheat-Bambara protein isolate…”
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Multidirectional inhibition of cortico-hippocampal neurodegeneration by kolaviron treatment in rats
Published in Metabolic brain disease (01-08-2017)“…Earliest signs of neurodegenerative cascades in the course of Alzheimer’s disease (AD) are seen within the prefrontal cortex (PFC) and hippocampus, with…”
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Reversal of behavioral decline and neuropathology by a complex vitamin supplement involves modulation of key neurochemical stressors
Published in Environmental toxicology and pharmacology (01-09-2018)“…•B-complex vitamins plus ascorbic acid reverses behavioral decline and neuropathology•Inhibition of neurochemical and cellular imbalances in key brain areas…”
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Protective effects of Allium cepa-fortified feed on testicular function alterations by potassium bromate-induced oxidative damage: an in vivo and in silico approach
Published in Comparative clinical pathology (2024)“…Human infertility can arise from various factors including oxidative stress and endocrine disruptors. This study evaluated the protective effects of Allium…”
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Modulatory effect of cashew (Anacardiumoccidentale L.) nut supplemented diet on fertility activity of clomiphene citrate in male rats
Published in Biomedical journal (01-04-2021)“…Increasing concern has been expressed about the declining sperm count of humans and the potential fertility effects of clomiphene citrate, a synthetic…”
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Modulatory effect of cashew (Anacardium occidentale L.) nut supplemented diet on fertility activity of clomiphene citrate in male ratsAt a glance commentary
Published in Biomedical Journal (01-04-2021)“…Background: Increasing concern has been expressed about the declining sperm count of humans and the potential fertility effects of clomiphene citrate, a…”
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Glucocorticoid receptor activation selectively influence performance of Wistar rats in Y-maze
Published in Pathophysiology (Amsterdam) (01-03-2018)“…Glucocorticoid receptors (GR) are ubiquitously expressed in metazoans. Different and contrasting phenotypes have been reported upon their activation. This…”
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Glucocorticoid receptor activation selectively influence performance of Wistar rats in Y-maze
Published in Pathophysiology (Amsterdam) (09-12-2017)“…Glucocorticoid receptors (GR) are ubiquitously expressed in metazoans. Different and contrasting phenotypes have been reported upon their activation. This…”
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Cerebellar Molecular and Cellular Characterization in Rat Models of Alzheimer's Disease: Neuroprotective Mechanisms of Garcinia Biflavonoid Complex
Published in Annals of Neurosciences (01-05-2017)“…Background: Recent evidences suggest that cerebellar degeneration may be associated with the development of Alzheimer's disease (AD). However, previous reports…”
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