Search Results - "Asogun, Danny"
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Lassa Fever: Epidemiology, Clinical Features, Diagnosis, Management and Prevention
Published in Infectious disease clinics of North America (01-12-2019)“…Lassa fever outbreaks West Africa have caused up to 10,000 deaths annually. Primary infection occurs from contact with Lassa virus-infected rodents and…”
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Emergence of new SARS-CoV-2 Variant of Concern Omicron (B.1.1.529) - highlights Africa's research capabilities, but exposes major knowledge gaps, inequities of vaccine distribution, inadequacies in global COVID-19 response and control efforts
Published in International journal of infectious diseases (01-01-2022)Get full text
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Increased outbreaks of monkeypox highlight gaps in actual disease burden in Sub-Saharan Africa and in animal reservoirs
Published in International journal of infectious diseases (01-09-2022)“…•We present explanation for the 2022 monkeypox epidemic in the Western world•The true burden of MPX and the extent of animal reservoirs are not well known•The…”
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Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits
Published in Nature communications (10-05-2016)“…Lassa fever is a severe multisystem disease that often has haemorrhagic manifestations. The epitopes of the Lassa virus (LASV) surface glycoproteins recognized…”
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Phylogeography of Lassa Virus in Nigeria
Published in Journal of virology (01-11-2019)“…Lassa virus is genetically diverse with several lineages circulating in West Africa. This study aimed at describing the sequence variability of Lassa virus…”
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Monkeypox — Enhancing public health preparedness for an emerging lethal human zoonotic epidemic threat in the wake of the smallpox post-eradication era
Published in International journal of infectious diseases (01-01-2019)“…•Three patients were diagnosed with monkeypox in the United Kingdom in September 2018 the index case being from Nigeria.•Nigeria is currently experiencing a…”
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Lockdown measures in response to COVID-19 in nine sub-Saharan African countries
Published in BMJ global health (01-10-2020)“…Lockdown measures have been introduced worldwide to contain the transmission of COVID-19. However, the term ‘lockdown’ is not well-defined. Indeed, WHO’s…”
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Clinical and laboratory predictors of Lassa fever outcome in a dedicated treatment facility in Nigeria: a retrospective, observational cohort study
Published in The Lancet infectious diseases (01-06-2018)“…Lassa fever is a viral haemorrhagic disease endemic to west Africa. No large-scale studies exist from Nigeria, where the Lassa virus (LASV) is most diverse…”
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Tuberculosis, HIV/AIDS and Malaria Health Services in sub-Saharan Africa – A Situation Analysis of the Disruptions and Impact of the COVID-19 Pandemic
Published in International journal of infectious diseases (01-11-2022)“…•The COVID-19 pandemic has impacted negatively on Africa's health systems•COVID-19 disruptions on TB and other health services need to be urgently…”
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Prevalence of Lassa Virus Disease (LVD) in Nigerian children with fever or fever and convulsions in an endemic area
Published in PLoS neglected tropical diseases (01-07-2017)“…Convulsions with fever in children are a common neurologic emergency in the tropics, and determining the contribution of endemic viral infections can be…”
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Molecular diagnostics for lassa fever at Irrua specialist teaching hospital, Nigeria: lessons learnt from two years of laboratory operation
Published in PLoS neglected tropical diseases (01-09-2012)“…Lassa fever is a viral hemorrhagic fever endemic in West Africa. However, none of the hospitals in the endemic areas of Nigeria has the capacity to perform…”
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Development and evaluation of antibody-capture immunoassays for detection of Lassa virus nucleoprotein-specific immunoglobulin M and G
Published in PLoS neglected tropical diseases (29-03-2018)“…The classical method for detection of Lassa virus-specific antibodies is the immunofluorescence assay (IFA) using virus-infected cells as antigen. However, IFA…”
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Focussed Assessment with Sonography in acute Lassa Fever (FASLa): Development of a point-of-care protocol and description of common ultrasound findings
Published in The Journal of infection (01-07-2023)“…Managing Lassa fever (LF) patients is challenging because of the complexity of this life-threatening infectious disease, the necessary isolation measures, and…”
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Discovery of novel rhabdoviruses in the blood of healthy individuals from West Africa
Published in PLoS neglected tropical diseases (01-03-2015)“…Next-generation sequencing (NGS) has the potential to transform the discovery of viruses causing unexplained acute febrile illness (UAFI) because it does not…”
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A national survey of hospital readiness during the COVID-19 pandemic in Nigeria
Published in PloS one (21-09-2021)“…The COVID-19 pandemic continues to overwhelm health systems across the globe. We aimed to assess the readiness of hospitals in Nigeria to respond to the…”
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A prospective, multi-site, cohort study to estimate incidence of infection and disease due to Lassa fever virus in West African countries (the Enable Lassa research programme)-Study protocol
Published in PloS one (30-03-2023)“…Lassa fever (LF), a haemorrhagic illness caused by the Lassa fever virus (LASV), is endemic in West Africa and causes 5000 fatalities every year. The true…”
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Lassa fever outbreaks in Nigeria
Published in Expert review of anti-infective therapy (02-09-2018)Get more information
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Retrospective Cohort Study of Lassa Fever in Pregnancy, Southern Nigeria
Published in Emerging infectious diseases (01-08-2019)“…The positive outcomes observed support a conservative approach to disease management. Lassa fever in pregnancy causes high rates of maternal and fetal death,…”
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Factors associated with progression to death in patients with Lassa fever in Nigeria: an observational study
Published in The Lancet infectious diseases (01-06-2021)“…Lassa fever is endemic in several west African countries. Case-fatality rates ranging from 21% to 69% have been reported. The pathophysiology of the disease in…”
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