Search Results - "Asnawi, Syafiq"
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1
Receptor Tyrosine Kinases and Their Signaling Pathways as Therapeutic Targets of Curcumin in Cancer
Published in Frontiers in pharmacology (15-11-2021)“…Receptor tyrosine kinases (RTKs) are transmembrane cell-surface proteins that act as signal transducers. They regulate essential cellular processes like…”
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2
A scaffolded approach to unearth potential antibacterial components from epicarp of Malaysian Nephelium lappaceum L
Published in Scientific reports (05-07-2021)“…The emergence and spread of antimicrobial resistance have been of serious concern to human health and the management of bacterial infectious diseases…”
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3
The Crosstalk Between Signaling Pathways and Cancer Metabolism in Colorectal Cancer
Published in Frontiers in pharmacology (23-11-2021)“…Colorectal cancer (CRC) is one of the most frequently diagnosed cancers worldwide. Metabolic reprogramming represents an important cancer hallmark in CRC…”
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4
Deciphering the toxicological and computational assessment of Verbascum yemenese.: Integrating phytochemistry and bioinformatics tools
Published in Food and chemical toxicology (01-11-2024)“…This study explores the phytochemical composition and biological activities of Verbascum yemenense, a plant known for its medicinal properties. The plant…”
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5
Potential economic and clinical implications of improving access to snake antivenom in five ASEAN countries: A cost-effectiveness analysis
Published in PLoS neglected tropical diseases (01-11-2022)“…Despite domestic production of antivenoms in the Association of Southeast Asian Nations (ASEAN) countries, not all victims with snakebite envenomings indicated…”
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6
Estimating economic and disease burden of snakebite in ASEAN countries using a decision analytic model
Published in PLoS neglected tropical diseases (01-09-2022)“…Understanding the burden of snakebite is crucial for developing evidence-informed strategies to pursue the goal set by the World Health Organization to halve…”
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7
Antiviral Activities of Streptomyces KSF 103 Methanolic Extracts against Dengue Virus Type-2
Published in Viruses (20-08-2023)“…Dengue has long been a serious health burden to the global community, especially for those living in the tropics. Despite the availability of vaccines,…”
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8
Insights into the Role of microRNAs in Colorectal Cancer (CRC) Metabolism
Published in Cancers (01-09-2020)“…Colorectal cancer (CRC) is one of the most frequently diagnosed cancers, with a high mortality rate globally. The pathophysiology of CRC is mainly initiated by…”
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Investigation into the biological properties, secondary metabolites composition, and toxicity of aerial and root parts of Capparis spinosa L.: An important medicinal food plant
Published in Food and chemical toxicology (01-09-2021)“…Capparis spinose L. also known as Caper is of great significance as a traditional medicinal food plant. The present work was targeted on the determination of…”
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10
In vitro biological propensities and chemical profiling of Euphorbia milii Des Moul (Euphorbiaceae): A novel source for bioactive agents
Published in Industrial crops and products (01-04-2019)“…•Biological and chemical properties of Euphorbia milii different parts were investigated.•Six in-vitro antioxidant assays were performed.•Inhibition potential…”
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11
Anti-Cancer Mechanisms of Diarylpentanoid MS17 (1,5-Bis(2-hydroxyphenyl)-1,4-pentadiene-3-one) in Human Colon Cancer Cells: A Proteomics Approach
Published in International journal of molecular sciences (20-03-2024)“…Diarylpentanoids are synthesized to overcome curcumin's poor bioavailability and low stability to show enhanced anti-cancer effects. Little is known about the…”
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12
Chronic unpredictable stress (CUS) reduced phoenixin expression, induced abnormal sperm and testis morphology in male rats
Published in Neuropeptides (Edinburgh) (01-10-2024)“…Chronic stress caused by prolonged emotional pressure can lead to various physiological issues, including reproductive dysfunction. Although reproductive…”
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13
Investigation of phytochemical composition and enzyme inhibitory potential of Anagallis arvensis L
Published in Natural product research (01-07-2022)“…L. commonly known as 'Scarlet Pimpernel' has been used in folklore as natural remedy for treating common ailments. The present research is aimed to explore the…”
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14
Flavonoids as receptor tyrosine kinase inhibitors in lung cancer
Published in Journal of functional foods (01-11-2023)“…[Display omitted] •Flavonoids exert anti-lung cancer effects via RTK modulation.•Flavonoids mainly inhibit signalling pathways like MAPK, PI3K/Akt and…”
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15
Evaluation of the Phytochemical, Antioxidant, Enzyme Inhibition, and Wound Healing Potential of Calotropis gigantea (L.) Dryand: A Source of a Bioactive Medicinal Product
Published in Frontiers in pharmacology (17-08-2021)“…Traditionally, plants of the genus Calotropis have been used to cure various common diseases. The present research work explores the chemical and biological…”
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16
Pharmacological, phytochemical and in-vivo toxicological perspectives of a xero-halophyte medicinal plant: Zaleya pentandra (L.) Jeffrey
Published in Food and chemical toxicology (01-09-2019)“…This study endeavours to investigate the phytochemical composition, biological properties and in vivo toxicity of methanol and dichloromethane extracts of…”
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17
The utilization of small non‐mammals in traumatic brain injury research: A systematic review
Published in CNS neuroscience & therapeutics (01-04-2021)“…Traumatic brain injury (TBI) is the leading cause of death and disability worldwide and has complicated underlying pathophysiology. Numerous TBI animal models…”
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18
Krebs Cycle Intermediate-Modified Carbonate Apatite Nanoparticles Drastically Reduce Mouse Tumor Burden and Toxicity by Restricting Broad Tissue Distribution of Anticancer Drugs
Published in Cancers (09-01-2020)“…The morphology, size, and surface area of nanoparticles (NPs), with the existence of functional groups on their surface, contribute to the drug binding…”
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19
Pilocarpine Induced Behavioral and Biochemical Alterations in Chronic Seizure-Like Condition in Adult Zebrafish
Published in International journal of molecular sciences (03-04-2020)“…Epilepsy is a devastating neurological condition exhibited by repeated spontaneous and unpredictable seizures afflicting around 70 million people globally. The…”
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20
Animal Venoms as Potential Source of Anticonvulsants [version 1; peer review: 3 approved]
Published in F1000 research (2024)“…Abstract* Epilepsy affects millions of people worldwide, and there is an urgent need to develop safe and effective therapeutic agents. Animal venoms contain…”
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