Search Results - "Asmar, Meena"
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The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor
Published in Diabetes (New York, N.Y.) (01-09-2017)“…A truncated form of human glucose-dependent insulinotropic polypeptide (GIP), GIP(3-30)NH , was recently identified as an antagonist of the human GIP receptor…”
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The Glucagonostatic and Insulinotropic Effects of Glucagon-Like Peptide 1 Contribute Equally to Its Glucose-Lowering Action
Published in Diabetes (New York, N.Y.) (01-07-2010)“…Glucagon-like peptide 1 (GLP-1) exerts beneficial antidiabetic actions via effects on pancreatic beta- and alpha-cells. Previous studies have focused on the…”
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Renal extraction and acute effects of glucagon-like peptide-1 on central and renal hemodynamics in healthy men
Published in American journal of physiology: endocrinology and metabolism (15-04-2015)“…The present experiments were performed to elucidate the acute effects of intravenous infusion of glucagon-like peptide (GLP)-1 on central and renal…”
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Glucose-Dependent Insulinotropic Polypeptide May Enhance Fatty Acid Re-esterification in Subcutaneous Abdominal Adipose Tissue in Lean Humans
Published in Diabetes (New York, N.Y.) (01-09-2010)“…Glucose-dependent insulinotropic polypeptide (GIP) has been implicated in lipid metabolism in animals. In humans, however, there is no clear evidence of GIP…”
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GIP-induced vasodilation in human adipose tissue involves capillary recruitment
Published in Endocrine Connections (01-06-2019)“…Glucose-dependent insulinotropic polypeptide (GIP) in combination with hyperinsulinemia increase blood flow and triglyceride clearance in subcutaneous…”
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Preserved Inhibitory Potency of GLP-1 on Glucagon Secretion in Type 2 Diabetes Mellitus
Published in The journal of clinical endocrinology and metabolism (01-12-2009)“…Objective: Glucagon-like peptide-1 (GLP-1) is insulinotropic, but its effect on the α-cell is less clear. We investigated the dose-response relationship for…”
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A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite
Published in American journal of physiology: endocrinology and metabolism (01-09-2017)“…Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from the gastrointestinal tract. It is best known for its glucose-dependent insulinotropic…”
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Searching for the physiological role of glucose‐dependent insulinotropic polypeptide
Published in Journal of diabetes investigation (01-04-2016)“…Glucose‐dependent insulinotropic polypeptide (GIP) was established as a gut hormone more than 40 years ago, and there is good experimental support for its role…”
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Increased oral sodium chloride intake in humans amplifies selectively postprandial GLP‐1 but not GIP, CCK, and gastrin in plasma
Published in Physiological reports (01-08-2020)“…Human studies have demonstrated that physiologically relevant changes in circulating glucagon‐like peptide‐1 (GLP‐1) elicit a rapid increase in renal sodium…”
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ADAM12 induces actin cytoskeleton and extracellular matrix reorganization during early adipocyte differentiation by regulating β1 integrin function
Published in Journal of cell science (01-10-2003)“…Changes in cell shape are a morphological hallmark of differentiation. In this study we report that the expression of ADAM12, a disintegrin and…”
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Insulin Plays a Permissive Role for the Vasoactive Effect of GIP Regulating Adipose Tissue Metabolism in Humans
Published in The journal of clinical endocrinology and metabolism (01-08-2016)“…Context and Objective: Glucose-dependent insulinotropic polypeptide (GIP) in combination with hyperinsulinemia increases blood flow and triglyceride (TAG)…”
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1957-P: The Role of Glucose-Dependent Insulinotropic Polypeptide in Regulation of Splanchnic Blood Flow and Lipid Metabolism in Humans
Published in Diabetes (New York, N.Y.) (01-06-2019)“…The aim of this study was to investigate the effect of glucose-dependent insulinotropic polypeptide (GIP) per se and in combination with hyperglycemia and…”
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Gastrin secretion in normal subjects and diabetes patients is inhibited by glucagon-like peptide 1: a role in the gastric side effects of GLP-1-derived drugs?
Published in Scandinavian journal of gastroenterology (02-12-2019)“…Background: Randomized and controlled trials of glucagon-like peptide-1 (GLP-1) derived drugs have shown that the most frequent adverse symptoms are…”
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Glucose-dependent insulinotropic polypeptide increases blood flow in adipose tissue of humans by recruiting capillaries
Published in The journal of clinical endocrinology and metabolism (01-01-2019)“…Glucose-dependent insulinotropic polypeptide (GIP) in combination with hyperinsulinemia increase blood flow and triglyceride clearance in subcutaneous…”
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Cholecystokinin secretion is suppressed by glucagon-like peptide-1: clue to the mechanism of the adverse gallbladder events of GLP-1-derived drugs
Published in Scandinavian journal of gastroenterology (02-12-2018)“…Recent randomized and controlled trials of drugs derived from the gut hormone glucagon-like peptide-1 (GLP-1) show that the most frequent adverse symptoms are…”
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Extracellular Fluid Volume Expansion Uncovers a Natriuretic Action of GLP-1: A Functional GLP-1–Renal Axis in Man
Published in The journal of clinical endocrinology and metabolism (01-07-2019)“…Abstract Purpose We have previously demonstrated that glucagon-like peptide-1 (GLP-1) does not affect renal hemodynamics or function under baseline conditions…”
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The Renal Extraction and the Natriuretic Action of GLP-1 in Humans Depend on Interaction With the GLP-1 Receptor
Published in The journal of clinical endocrinology and metabolism (01-01-2021)“…Abstract Purpose The natriuretic effect of glucagon-like peptide-1 (GLP-1) in humans is independent of changes in renal plasma flow (RPF) and glomerular…”
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WITHDRAWN: Glucose-Dependent Insulinotropic Polypeptide Increases Blood Flow in Adipose Tissue of Humans by Recruiting Capillaries
Published in The journal of clinical endocrinology and metabolism (01-01-2019)“…Context and Objective: Glucose-dependent insulinotropic polypeptide (GIP) in combination with hyperinsulinemia increases blood flow and triglyceride clearance…”
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Glucagon-like peptide-1 does not have acute effects on central or renal hemodynamics in patients with type 2 diabetes without nephropathy
Published in American journal of physiology: endocrinology and metabolism (01-05-2016)“…During acute administration of native glucagon-like peptide-1 (GLP-1), we previously demonstrated central hemodynamic effects in healthy males, whereas renal…”
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Effect of Glucagon-Like Peptide-1 on α- and β-Cell Function in C-Peptide-Negative Type 1 Diabetic Patients
Published in The journal of clinical endocrinology and metabolism (01-05-2010)“…Context: The mechanism by which glucagon-like peptide-1 (GLP-1) suppresses glucagon secretion is uncertain, and it is not determined whether endogenous insulin…”
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