Search Results - "Asmal, M."

LentiGlobin gene therapy for transfusion-dependent β-Thalassemia: Update from the northstar HGB-204 phase 1/2 clinical study by Rasko, J, Thompson, A, Kwiatkowski, J, Hongeng, S, Schiller, G.J, Anurathapan, U, Cavazzana-Calvo, M, Ho, P, von Kalle, C, Kletzel, M, Leboulch, P, Vichinsky, E, Petrusich, A, Asmal, M, Walters, M

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P03-07. Autologous neutralizing antibodies that select viral escape variants emerge late after SIV infection of rhesus monkeys by Yeh, WW, Rahman, I, Hraber, P, Giri, A, Nevidomskyte, D, Coffey, RT, Asmal, M, Miljkovic, S, Whitney, JB, Keele, BF, Shaw, GM, Korber, BT, Seaman, MS, Letvin, NL

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VX-970, selective inhibitor of ataxia telangiectasia and Rad3-related (ATR) protein by Asmal, M., Dean, E., Evans, J., Middleton, M., Plummer, R.

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O6.4VX-970, selective inhibitor of ataxia telangiectasia and Rad3-related (ATR) protein by Asmal, M, Dean, E, Evans, J, Middleton, M, Plummer, R

“…Background: ATR is a critical regulator of the homologous recombination DNA repair pathway and the cellular response to replication stress. Inhibition of ATR…”
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Cyclophilin A Regulates TCR Signal Strength in CD4 + T Cells via a Proline-Directed Conformational Switch in Itk by Colgan, John, Asmal, Mohammed, Neagu, Martha, Yu, Bin, Schneidkraut, Jason, Lee, Youngnam, Sokolskaja, Elena, Andreotti, Amy, Luban, Jeremy

“…Cyclophilin A (CypA/Ppia) is a peptidyl-prolyl isomerase (PPIase) that binds the immunosuppressive drug cyclosporine. The resulting complex blocks T cell…”
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Efficacy and safety of LentiGlobin gene therapy in patients with transfusion-dependent β-thalassemia and non-β0/β0 genotypes: Updated results from the completed phase 1/2 Northstar and ongoing phase 3 Northstar-2 studies by Rasko, J., Walters, M., Kwiatkowski, J., Hongeng, S., Porter, J., Sauer, M., Thrasher, A., Thuret, I., Schiller, G., Elliot, H., Deary, B., Chen, Y., Tao, G., Asmal, M., Locatelli, F., Thompson, A.

“…Although advances in red blood cell (RBC) transfusion and iron chelation have improved the prognosis of patients with transfusion-dependent β-thalassemia…”
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Efficacy and safety of LentiGlobin gene therapy in patients with transfusion-dependent β-thalassemia and non-β 0/β 0 genotypes: Updated results from the completed phase 1/2 Northstar and ongoing phase 3 Northstar-2 studies by Rasko, J, Walters, M, Kwiatkowski, J, Hongeng, S, Porter, J, Sauer, M, Thrasher, A, Thuret, I, Schiller, G, Elliot, H, Deary, B, Chen, Y, Tao, G, Asmal, M, Locatelli, F, Thompson, A

“…Background & AimAlthough advances in red blood cell (RBC) transfusion and iron chelation have improved the prognosis of patients with transfusion-dependent…”
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Cyclophilin A-Deficient Mice Are Resistant to Immunosuppression by Cyclosporine by Colgan, John, Asmal, Mohammed, Yu, Bin, Luban, Jeremy

“…Cyclosporine is an immunosuppressive drug that is widely used to prevent organ transplant rejection. Known intracellular ligands for cyclosporine include the…”
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29 - LentiGlobin gene therapy for transfusion-dependent β-Thalassemia: Update from the northstar HGB-204 phase 1/2 clinical study by Rasko, J., Thompson, A., Kwiatkowski, J., Hongeng, S., Schiller, G.J., Anurathapan, U., Cavazzana-Calvo, M., Ho, P., von Kalle, C., Kletzel, M., Leboulch, P., Vichinsky, E., Petrusich, A., Asmal, M., Walters, M.

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PF441 RED BLOOD CELLS PROPERTIES IN PATIENTS WITH SICKLE CELL DISEASE TREATED WITH LENTIGLOBIN GENE THERAPY IN THE HGB‐205 TRIAL by Magrin, E., Semeraro, M., Hebert, N., Kiger, L., Nguyen‐Peyre, K.‐A., Joseph, L., Miccio, A., Chalumeau, A., Magnani, A., Couzin, C., Marouene, J., Gabrion, A., Roudaut, C., El Nemer, W., Pirenne, F., Negre, O., Ribeil, J.‐A., Brousse, V., De Montalembert, M., Asmal, M., Bartolucci, P., Cavazzana, M.

“…Background: Sickle cell disease (SCD) is one of the most prevalent inherited disorders worldwide. The ex vivo gene therapy phase 1/2 study HGB‐205 conducted in…”
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Production of Ribosome Components in Effector CD4 + T Cells Is Accelerated by TCR Stimulation and Coordinated by ERK-MAPK by Asmal, Mohammed, Colgan, John, Naef, Felix, Yu, Bin, Lee, Youngnam, Magnasco, Marcelo, Luban, Jeremy

“…Effector CD4 + T cells rapidly activate high-level cytokine expression following TCR stimulation. Consistent with accelerated protein production in these…”
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Isolation, Characterization and Targeted Disruption of Mouse Ppia: Cyclophilin A Is Not Essential for Mammalian Cell Viability by Colgan, John, Asmal, Mohammed, Luban, Jeremy

“…Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity…”
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Production of Ribosome Components in Effector CD4 super(+) T Cells Is Accelerated by TCR Stimulation and Coordinated by ERK-MAPK by Asmal, M, Colgan, J, Naef, F, Yu, B, Lee, Y, Magnasco, M, Luban, J

“…Effector CD4 super(+) T cells rapidly activate high-level cytokine expression following TCR stimulation. Consistent with accelerated protein production in…”
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Cyclophilin A Regulates TCR Signal Strength in CD4 super(+) T Cells via a Proline-Directed Conformational Switch in Itk by Colgan, J, Asmal, M, Neagu, M, Yu, B, Schneidkraut, J, Lee, Y, Sokolskaja, E, Andreotti, A, Luban, J

“…Cyclophilin A (CypA/Ppia) is a peptidyl-prolyl isomerase (PPIase) that binds the immunosuppressive drug cyclosporine. The resulting complex blocks T cell…”
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Non-immune hydrops and superior vena cava syndrome due to diaphragmatic hernia in one twin by Asmal, Mohammed, Suri, Mandhir, Ruzal-Shapiro, Carrie B, Baxi, Laxmi V

“…In a monochorionic twin gestation, hydrops in one fetus often results from placental transfusion, accompanied by intrauterine growth restriction (IUGR) of the…”
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Surma (Eye Cosmetic): The Gift that can be Dangerous by Aslam, Tariq, Asmal, M

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BRISMES 1994 Annual Conference by Abu-Bakr M. Asmal

“…The annual conference of the British Society for Middle Eastern Studies (BRISMES) was hosted by the Department of Middle Eastern Studies at the University of…”
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A Fundamental Fear - Eurocentrism and the Emergence of Islamism (by Bobby S. Sayyid) (Book Review) by Asmal, A M

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BRISMES 1994 Annual Conference by Asmal, Abu-Bakr M

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The phytohaemagglutinin response and lymphocyte subpopulations in young Blacks and Indians with insulin-dependent diabetes mellitus by Omar, M.A.K., Pudifin, D.J., Coovadia, H.M., Duursma, J., Kiepiela, F., Stretton, M. & Asmal, A.C

“…The lymphocyte transformation response to phytohaemagglutinin (PHA) and the relative numbers of T, B and null lymphocytes were studied in 32 insulin-dependent…”
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