Search Results - "Askovich, Peter S."
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25-Hydroxycholesterol acts as an amplifier of inflammatory signaling
Published in Proceedings of the National Academy of Sciences - PNAS (22-07-2014)“…Cross-talk between sterol regulatory pathways and inflammatory pathways has been demonstrated to significantly impact the development of both atherosclerosis…”
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miR-451 regulates dendritic cell cytokine responses to influenza infection
Published in The Journal of immunology (1950) (15-12-2012)“…MicroRNAs (miRNAs) are important posttranscriptional regulators in immune cells, but how viral infection regulates miRNA expression to shape dendritic cell…”
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Identifying novel transcription factors involved in the inflammatory response by using binding site motif scanning in genomic regions defined by histone acetylation
Published in PloS one (18-09-2017)“…The innate immune response to pathogenic challenge is a complex, multi-staged process involving thousands of genes. While numerous transcription factors that…”
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Differential host response, rather than early viral replication efficiency, correlates with pathogenicity caused by influenza viruses
Published in PloS one (20-09-2013)“…Influenza viruses exhibit large, strain-dependent differences in pathogenicity in mammalian hosts. Although the characteristics of severe disease, including…”
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5
Characterization of innate responses to influenza virus infection in a novel lung type I epithelial cell model
Published in Journal of general virology (01-02-2014)“…Type I alveolar epithelial cells are a replicative niche for influenza in vivo, yet their response to infection is not fully understood. To better characterize…”
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A novel small molecule target in human airway smooth muscle for potential treatment of obstructive lung diseases: a staged high-throughput biophysical screening
Published in Respiratory research (13-01-2011)“…A newly identified mechanism of smooth muscle relaxation is the interaction between the small heat shock protein 20 (HSP20) and 14-3-3 proteins. Focusing upon…”
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miR-451 regulates dendritic cell cytokine responses to influenza infection1
Published in The Journal of immunology (1950) (19-11-2012)“…MicroRNAs are important post-transcriptional regulators in immune cells, but how viral infection regulates microRNA expression to shape dendritic cell…”
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A comprehensive collection of systems biology data characterizing the host response to viral infection
Published in Scientific data (14-10-2014)“…The Systems Biology for Infectious Diseases Research program was established by the U.S. National Institute of Allergy and Infectious Diseases to investigate…”
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Differential Host Response, Rather Than Early Viral Replication Efficiency, Correlates with Pathogenicity Caused by Influenza Viruses: e74863
Published in PloS one (01-09-2013)“…Influenza viruses exhibit large, strain-dependent differences in pathogenicity in mammalian hosts. Although the characteristics of severe disease, including…”
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