Search Results - "Asin, Enrique"

Context matters: On the road to responsible biosafety technologies in synthetic biology by Kallergi, Amalia, Asin-Garcia, Enrique, Martins dos Santos, Vitor AP, Landeweerd, Laurens

“…Graphical Abstract Biosafety is a major challenge for developing for synthetic organisms. An early focus on application and their context could assist with the…”
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From Innovation to Application: Bridging the Valley of Death in Industrial Biotechnology by Kampers, Linde F.C., Asin-Garcia, Enrique, Schaap, Peter J., Wagemakers, Annemarie, Martins dos Santos, Vitor A.P.

“…Few biotechnology innovations make it through the Valley of Death to markets. Based on our experience with academia, technology transfer offices, and industry,…”
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Phosphite synthetic auxotrophy as an effective biocontainment strategy for the industrial chassis Pseudomonas putida by Asin-Garcia, Enrique, Batianis, Christos, Li, Yunsong, Fawcett, James D, de Jong, Ivar, Dos Santos, Vitor A P Martins

“…The inclusion of biosafety strategies into strain engineering pipelines is crucial for safe-by-design biobased processes. This in turn might enable a more…”
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Multilayered safety framework for living diagnostics in the colon by Mecacci, Sonia, Torregrosa-Barragán, Lucía, Asin-Garcia, Enrique, Smith, Robert W.

“…Introduction: Colorectal cancer is the second most deadly cancer worldwide. Current screening methods have low detection rates and frequently provide false…”
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GenoMine: a CRISPR-Cas9-based kill switch for biocontainment of Pseudomonas putida by Asin-Garcia, Enrique, Martin-Pascual, Maria, de Buck, Claudia, Allewijn, Max, Müller, Alexandra, Martins Dos Santos, Vitor A P

“…Synthetic genetic circuits have revolutionised our capacity to control cell viability by conferring microorganisms with programmable functionalities to limit…”
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Navigating the Valley of Death: Perceptions of Industry and Academia on Production Platforms and Opportunities in Biotechnology by Kampers, Linde F.C., Asin-Garcia, Enrique, Schaap, Peter J., Wagemakers, Annemarie, Martins dos Santos, Vitor A.P.

“…Rational lifestyle engineering has improved performance of microbial cell factories in Industrial Biotechnology. However, few innovations make it through the…”
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Identification of Aspergillus niger Aquaporins Involved in Hydrogen Peroxide Signaling by Laothanachareon, Thanaporn, Asin-Garcia, Enrique, Volkers, Rita J M, Tamayo-Ramos, Juan Antonio, Martins Dos Santos, Vitor A P, Schaap, Peter J

“…is a robust microbial cell factory for organic acid production. However, the regulation of many industrially important pathways is still poorly understood. The…”
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Prevalence of left ventricular hypertrophy detected by Cornell voltage-duration product in a hypertensive population by Barrios, Vivencio, Escobar, Carlos, Calderon, Alberto, Ribas, Leandre, Marti, David, Asin, Enrique

“…Detection and treatment of left ventricular hypertrophy (LVH) in hypertension is important in order to reduce cardiovascular risk. The product of QRS voltage…”
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Analysis of mortality in myocardial infarction patients treated with primary angioplasty by Salido, Luisa, Mestre, José Luis, Pey, Jaime, Barcia, Francisco, Asín, Enrique

“…Primary angioplasty is an effective method to achieve myocardial reperfusion in ST-elevated myocardial infarction (MI). The objective of this study was to…”
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Endothelial dysfunction, intima–media thickness and coronary reserve in relation to risk factors and Framingham score in patients without clinical atherosclerosis by Campuzano, Raquel, Moya, José L, García-Lledó, Alberto, Tomas, Juan P, Ruiz, Soledad, Megías, Alicia, Balaguer, Javier, Asín, Enrique

“…BACKGROUNDEndothelial dysfunction, decreased coronary flow reserve (CFR) and increased intima–media thickness (IMT) are related to atherosclerosis and can be…”
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High heart rate: More than a risk factor. Lessons from a clinical practice survey by Barrios, Vivencio, Escobar, Carlos, Bertomeu, Vicente, Murga, Nekane, de Pablo, Carmen, Asín, Enrique

“…Abstract Several epidemiological studies have reported that an elevated heart rate (HR) is associated with coronary atherosclerosis independently of other risk…”
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Regression of left ventricular hypertrophy in diabetics by a candesartan-based regimen in clinical practice by Barrios, Vivencio, Escobar, Carlos, Calderón, Alberto, Vegazo, Onofre, Fernandez, Raúl, Asín, Enrique

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Current Analysis of the Results of the COURAGE Trial: Has an Optimal Treatment Been Reached in Clinical Practice? by Cardiel, Enrique Asín, Murga, Nekane

“…The COURAGE (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation) trial was designed to evaluate the benefits of percutaneous coronary…”
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A snapshot of biomanufacturing and the need for enabling research infrastructure by Asin-Garcia, Enrique, Fawcett, James D., Batianis, Christos, Martins dos Santos, Vitor A.P.

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A navigation guide of synthetic biology tools for Pseudomonas putida by Martin-Pascual, Maria, Batianis, Christos, Bruinsma, Lyon, Asin-Garcia, Enrique, Garcia-Morales, Luis, Weusthuis, Ruud A., van Kranenburg, Richard, Martins dos Santos, Vitor A.P.

“…Pseudomonas putida is a microbial chassis of huge potential for industrial and environmental biotechnology, owing to its remarkable metabolic versatility and…”
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Context matters by Kallergi, Amalia, Asin‐Garcia, Enrique, Martins dos Santos, Vitor AP, Landeweerd, Laurens

“…Biosafety is a major challenge for developing for synthetic organisms. An early focus on application and their context could assist with the design of…”
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Genetic Safeguards for Safety-by-design: So Close Yet So Far by Asin-Garcia, Enrique, Kallergi, Amalia, Landeweerd, Laurens, Martins dos Santos, Vitor A.P.

“…Safety-by-design (SbD) is paramount for risk management in synthetic biology, with genetic safeguards being a key technology for its implementation. While…”
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Metagenomics harvested genus-specific single-stranded DNA-annealing proteins improve and expand recombineering in Pseudomonas species by Asin-Garcia, Enrique, Garcia-Morales, Luis, Bartholet, Tessa, Liang, Zhuobin, Isaacs, Farren J, Martins dos Santos, Vitor A P

“…Abstract The widespread Pseudomonas genus comprises a collection of related species with remarkable abilities to degrade plastics and polluted wastes and to…”
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Safe Chassis: Engineering Biosafety for Industrial Biotechnology by García, Enrique Asín

“…Synthetic biologists design and engineer organisms for a better and more sustainable future. While the manifold prospects are encouraging, concerns about the…”
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SafeChassis: Engineering Biosafety for Industrial Biotechnology by García, Enrique Asín

“…This thesis was conceived within the framework of the research project “SafeChassis: Implementing and Assessing Safeguards for Lifestyle Engineering of a…”
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