Search Results - "Asiedu, Isaac"
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Prostate-specific antigen, digital rectal examination, and prostate cancer detection: A study based on more than 7000 transrectal ultrasound-guided prostate biopsies in Ghana
Published in Translational oncology (01-01-2025)“…•A large real-world data on prostate cancer detection in Ghanaian men using standard diagnostic tests - PSA, DRE, and biopsy.•The cancer detection rate was…”
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Autosomal dominant polycystic kidney disease with ectopic unilateral multicystic kidney: a case report
Published in Journal of medical case reports (09-01-2024)“…Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disorder and the fourth cause of death of end-stage renal disease. The…”
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Availability and Types of Pressure Ulcer Medications at Community Pharmacies in the Accra Metropolis of Ghana
Published in Innovations in pharmacy (2024)“…Pressure ulcers (PU) arise from prolonged pressure on the skin and underlying tissue due to pathological changes in blood flow. They usually develop in people…”
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In Vitro Antioxidant Potential and Effect of a Glutathione-Enhancer Dietary Supplement on Selected Rat Liver Cytochrome P450 Enzyme Activity
Published in Evidence-based complementary and alternative medicine (01-01-2018)“…Background. There is considerable evidence that many people take dietary supplements including those of herbal origin as an alternative therapy to improve…”
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Serum Iron Levels and Copper-to-Zinc Ratio in Sickle Cell Disease
Published in Medicina (Kaunas, Lithuania) (21-05-2019)“…: Altered copper and zinc homeostasis may influence the antioxidant defense system and consequently lead to oxidative stress and associated complications in…”
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A descriptive study of the single-nucleotide polymorphisms known to affect the Tacrolimus trough concentration per dose, among a population of kidney failure patients in a tertiary hospital in Ghana
Published in BMC research notes (29-07-2024)“…The burden of chronic kidney disease (CKD) and kidney failure in Ghana is on the ascendency, with the prevalence of CKD estimated at 13.3%. Patients with CKD…”
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Prevalence, Scope and Quality of Extemporaneous Medications in Selected Healthcare Facilities and Implications for Pharmacy Practice
Published in Innovations in pharmacy (2024)“…: Extemporaneous compounding is the preparation of medicines for individual patients when no commercially available authorized form exists. Unlike registered…”
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Phytotherapy of experimental depression: Kalanchoe integra Var. Crenata (Andr.) Cuf Leaf Extract
Published in Journal of pharmacy & bioallied science (01-01-2015)“…Kalanchoe sp. have been used since 1921 for central nervous system (CNS) disorders such as psychosis and depression. It is known to possess CNS depressant…”
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Antibacterial and antispasmodic activities of a dichloromethane fraction of an ethanol extract of stem bark of Piliostigma reticulatum
Published in Journal of pharmacy & bioallied science (01-04-2015)“…This study presents the antispasmodic and antibacterial properties of an ethanol extract and fractions the of stem bark of Piliostigma reticulatum. The…”
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Effect of Metaswitch® dietary supplement on anthropometric parameters, serum lipids, glucose level, oxidative stress and in vivo antioxidant properties in high fat diet-induced overweight Sprague Dawley rats
Published in Biomedicine & pharmacotherapy (01-05-2022)“…Obesity and overweight are metabolic disorders associated with oxidative stress, and risk factors for many chronic diseases. We sought to investigate the…”
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Antidepressant Potentials of Components from Trichilia monadelpha (Thonn.) J.J. de Wilde in Murine Models
Published in Evidence-based complementary and alternative medicine (01-01-2018)“…Trichilia monadelpha is a common medicinal plant used traditionally in treating central nervous system conditions such as epilepsy, depression, pain, and…”
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A Preliminary Safety Evaluation of Polyhexamethylene Guanidine Hydrochloride
Published in International journal of toxicology (01-11-2014)“…Polyhexamethylene guanidine hydrochloride (PHMGH) is used worldwide as an antimicrobial agent with broad spectra of activity and also for treating pool water…”
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Effect of Cellgevity® Supplement on Selected Rat Liver Cytochrome P450 Enzyme Activity and Pharmacokinetic Parameters of Carbamazepine
Published in Evidence-based complementary and alternative medicine (2020)“…Background. There is considerable evidence that many patients concurrently administer dietary supplements with conventional drugs, creating a risk for…”
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Ethanolic extract of Nymphaea lotus L. (Nymphaeaceae) leaves exhibits in vitro antioxidant, in vivo anti-inflammatory and cytotoxic activities on Jurkat and MCF-7 cancer cell lines
Published in BMC complementary and alternative medicine (07-01-2021)“…Nymphaea lotus L. (N. lotus) is an aquatic plant with anecdotal reports suggesting its use in the traditional management of cancer. However, there is a paucity…”
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Short-term administration of an aqueous extract of kalanchoe integra var. crenata (Andr.) Cuf leaves produces no major organ damage in Sprague-Dawley rats
Published in Journal of ethnopharmacology (03-02-2014)“…Kalanchoe intergra (Ki) leaf extract is an orally administered multipurpose plant medicine in Ghana and other parts of the world for the treatment of ulcers,…”
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Toxicological assessment of polyhexamethylene biguanide for water treatment
Published in Interdisciplinary toxicology (01-12-2015)“…Polyhexamethylene biguanide (PHMB) is an antiseptic with antiviral and antibacterial properties used in a variety of products including wound care dressings,…”
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Antidiabetic properties of an Ethanolic leaf extract of Launaea taraxacifolia (Willd.) Amin ex C. Jeffrey (Asteraceae) in SD rats
Published in Clinical phytoscience (05-12-2022)“…Background Diabetes Mellitus (DM) is a major health problem, with a global prevalence of 9.3%, 4.7% in Africa, and 2.5% in Ghana. Despite the availability of…”
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Oral amodiaquine microparticles repurposed for the treatment of visceral leishmaniasis
Published in Scientific African (01-09-2022)“…Leishmaniasis, a neglected tropical disease, is caused by parasites from the genus Leishmania and transmitted by the female phlebotamine sandfly. Visceral…”
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Contrasting Hygiene-Related Gastrointestinal Infections and Stress-Related Diseases at a Primary Health Care Facility within a Sub-Saharan African City: Before and during the COVID-19 Pandemic
Published in Diseases (22-12-2022)“…With the advent of the COVID-19 pandemic caused by SARS-CoV-2, protocols such as social distancing and upscaling of hygiene practices were implemented to limit…”
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Monoaminergic and L-arginine-no-cGMP pathways mediate the antidepressant–like action of alkaloids from the stem bark of Trichilia monadelpha
Published in Scientific African (01-07-2020)“…Background: The role of L-arginine-nitric oxide-cGMP and monoamine pathways in the pathophysiology of depression and as target for antidepressant drugs is well…”
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