Search Results - "Ashworth, Michael T"

Reappraising myocardial fibrosis in severe aortic stenosis: an invasive and non-invasive study in 133 patients by Treibel, Thomas A, López, Begoña, González, Arantxa, Menacho, Katia, Schofield, Rebecca S, Ravassa, Susana, Fontana, Marianna, White, Steven K, DiSalvo, Carmelo, Roberts, Neil, Ashworth, Michael T, Díez, Javier, Moon, James C

“…Abstract Aims To investigate myocardial fibrosis (MF) in a large series of severe aortic stenosis (AS) patients using invasive biopsy and non-invasive imaging…”
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Interstitial Lung Disease in Children Made Easier…Well, Almost by Semple, Thomas R, Ashworth, Michael T, Owens, Catherine M

“…Interstitial lung disease (ILD) in pediatric patients is different from that in adults, with a vast array of pathologic conditions unique to childhood, varied…”
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Measurement of myocardial extracellular volume fraction by using equilibrium contrast-enhanced CT: validation against histologic findings by Bandula, Steve, White, Steven K, Flett, Andrew S, Lawrence, David, Pugliese, Francesca, Ashworth, Michael T, Punwani, Shonit, Taylor, Stuart A, Moon, James C

“…To develop and validate equilibrium contrast material-enhanced computed tomography (CT) to measure myocardial extracellular volume (ECV) fraction by using a…”
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Filamin A (FLNA) mutation—A newcomer to the childhood interstitial lung disease (ChILD) classification by Shelmerdine, Susan C., Semple, Thomas, Wallis, Colin, Aurora, Paul, Moledina, Shahin, Ashworth, Michael T., Owens, Catherine M.

“…Aim Interstitial lung disease (ILD) in infants represents a rare and heterogenous group of disorders, distinct from those occurring in adults. In recent years…”
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Micro-CT Imaging of Pediatric Thyroglossal Duct Cysts: A Prospective Case Series by Frauenfelder, Claire, Shelmerdine, Susan C, Simcock, Ian C, Hall, Andrew, Hutchinson, John Ciaran, Ashworth, Michael T, Arthurs, Owen J, Butler, Colin R

“…To determine the feasibility of micro-CT as a high-resolution 3D imaging tool for thyroglossal duct cysts and to evaluate its role augmenting traditional…”
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Autopsy findings of co-sleeping-associated sudden unexpected deaths in infancy: Relationship between pathological features and asphyxial mode of death by Weber, Martin A, Risdon, R Anthony, Ashworth, Michael T, Malone, Marian, Sebire, Neil J

“…Aim:  Co‐sleeping is associated with increased risk of sudden unexpected death in infancy (SUDI)/sudden infant death syndrome (SIDS). The aim of this study is…”
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Equilibrium Contrast Cardiovascular Magnetic Resonance for the Measurement of Diffuse Myocardial Fibrosis: Preliminary Validation in Humans by FLETT, Andrew S, HAYWARD, Martin P, ASHWORTH, Michael T, HANSEN, Michael S, TAYLOR, Andrew M, ELLIOTT, Perry M, MCGREGOR, Christopher, MOON, James C

“…Diffuse myocardial fibrosis is a final end point in most cardiac diseases. It is missed by the cardiovascular magnetic resonance (CMR) late gadolinium…”
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Postmortem microfocus computed tomography for noninvasive autopsies: experience in >250 human fetuses by Shelmerdine, Susan C., Simcock, Ian C., Hutchinson, John Ciaran, Guy, Anna, Ashworth, Michael T., Sebire, Neil J., Arthurs, Owen J.

“…Noninvasive imaging autopsy alternatives for fetuses weighing <500 grams are limited. Microfocus computed tomography has been reported as a viable option in…”
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Chondroid and Osseous Metaplasia of the Central Fibrous Body in Adolescent Hearts with Mutations in TNNI3 and TNNT2 genes by Carreon, Chrystalle Katte, Sanders, Stephen P, Ashworth, Michael T

“…The histological spectrum of the central fibrous body (CFB) of the heart, particularly in humans, is not fully characterized. Herein, we describe the presence…”
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Micro-CT of tracheal stenosis in trisomy 21 by Shelmerdine, Susan C, Ashworth, Michael T, Calder, Alistair D, Muthialu, Nagarajan, Arthurs, Owen J

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Postmortem Cardiovascular Magnetic Resonance Imaging in Fetuses and Children: A Masked Comparison Study With Conventional Autopsy by Taylor, Andrew M, Sebire, Neil J, Ashworth, Michael T, Schievano, Silvia, Scott, Rosemary J, Wade, Angie, Chitty, Lyn S, Robertson, Nikki, Thayyil, Sudhin

“…BACKGROUND—Perinatal and pediatric autopsies have declined worldwide in the past decade. We compared the diagnostic accuracy of postmortem, cardiovascular…”
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Pleuroparenchymal fibroelastosis in patients with pulmonary disease secondary to bone marrow transplantation by von der Thüsen, Jan H, Hansell, David M, Tominaga, Masaki, Veys, Paul A, Ashworth, Michael T, Owens, Catherine M, Nicholson, Andrew G

“…This study presents four patients who underwent bone marrow transplantation and subsequently developed pleuroparenchymal fibroelastosis, hitherto reported as…”
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LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis by Peltzer, Nieves, Darding, Maurice, Montinaro, Antonella, Draber, Peter, Draberova, Helena, Kupka, Sebastian, Rieser, Eva, Fisher, Amanda, Hutchinson, Ciaran, Taraborrelli, Lucia, Hartwig, Torsten, Lafont, Elodie, Haas, Tobias L., Shimizu, Yutaka, Böiers, Charlotta, Sarr, Aida, Rickard, James, Alvarez-Diaz, Silvia, Ashworth, Michael T., Beal, Allison, Enver, Tariq, Bertin, John, Kaiser, William, Strasser, Andreas, Silke, John, Bouillet, Philippe, Walczak, Henning

“…The linear ubiquitin chain assembly complex (LUBAC) is required for optimal gene activation and prevention of cell death upon activation of immune receptors,…”
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Preclinical Optimization and Safety Studies of a New Lentiviral Gene Therapy for p47 phox -Deficient Chronic Granulomatous Disease by Schejtman, Andrea, Vetharoy, Winston, Choi, Uimook, Rivat, Christine, Theobald, Narda, Piras, Giuseppa, Leon-Rico, Diego, Buckland, Karen, Armenteros-Monterroso, Elena, Benedetti, Sara, Ashworth, Michael T, Rothe, Michael, Schambach, Axel, Gaspar, Hubert Bobby, Kang, Elizabeth M, Malech, Harry L, Thrasher, Adrian J, Santilli, Giorgia

“…Chronic granulomatous disease (CGD) is an inherited blood disorder of phagocytic cells that renders patients susceptible to infections and inflammation. A…”
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Equilibrium contrast CMR for the measurement of diffuse myocardial fibrosis by Flett, Andrew S, Harward, Martin, Ashworth, Michael T, Hansen, Michael S, Taylor, Andrew M, Kolvekar, Shyam, Yap, John, Elliott, Perry, McGregor, Christopher, Moon, James C

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Multiple Cardiac Rhabdomyomas Visualised Using Micro-CT in a Case of Tuberous Sclerosis by Hutchinson, J Ciaran, Ashworth, Michael T, Sebire, Neil J, Arthurs, Owen J

“…Cardiac rhabdomyoma is the most common tumour of the heart in infancy and childhood, representing approximately 60% of all primary cardiac tumours in these age…”
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Reference ranges for organ weights of infants at autopsy: results of >1,000 consecutive cases from a single centre by Pryce, Jeremy W, Bamber, Andrew R, Ashworth, Michael T, Kiho, Liina, Malone, Marian, Sebire, Neil J

“…Infancy is the most common period for childhood death, including both neonatal deaths from obstetric or medical complications and sudden unexpected infant…”
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Sudden unexpected infant deaths associated with car seats by Bamber, Andrew R., Pryce, Jeremy, Ashworth, Michael T., Sebire, Neil J.

“…The purpose of this study was to investigate the frequency, circumstances, demographics, and causes of death of infants dying while seated in car safety seats…”
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Immersion-related deaths in infants and children: autopsy experience from a specialist center by Bamber, Andrew R., Pryce, Jeremy W., Ashworth, Michael T., Sebire, Neil J.

“…Purpose To investigate the demographics, circumstances and autopsy findings in infants and children dying following immersion. Methods A retrospective review…”
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Difficulties in interpretation of post-mortem microbiology results in unexpected infant death: evidence from a multidisciplinary survey by Pryce, Jeremy W, Weber, Martin A, Hartley, John C, Ashworth, Michael T, Malone, Marian, Sebire, Neil J

“…Post-mortem (PM) microbiological investigations are recommended in cases of sudden unexpected death in infancy (SUDI), and infection is a recognised cause of…”
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