Search Results - "Ashworth, Jason"

Role of C-Reactive Protein at Sites of Inflammation and Infection by Sproston, Nicola R, Ashworth, Jason J

“…C-reactive protein (CRP) is an acute inflammatory protein that increases up to 1,000-fold at sites of infection or inflammation. CRP is produced as a…”
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Tumor necrosis factor-alpha (TNF-α) is a therapeutic target for impaired cutaneous wound healing by Ashcroft, Gillian S., Jeong, Moon-Jin, Ashworth, Jason J., Hardman, Matthew, Jin, Wenwen, Moutsopoulos, Niki, Wild, Teresa, McCartney-Francis, Nancy, Sim, Davis, McGrady, George, Song, Xiao-yu, Wahl, Sharon M.

“…Impaired wound healing states lead to substantial morbidity and cost with treatment resulting in an expenditure of billions of dollars per annum in the US…”
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Health-related effects and improving extractability of cereal arabinoxylans by Fadel, Abdulmannan, Mahmoud, Ayman M., Ashworth, Jason J., Li, Weili, Ng, Yu Lam, Plunkett, Andrew

“…[Display omitted] •Arabinoxylans (AXs) are major dietary fiber found in many cereals.•AXs consumption has many health benefits.•Several methods are used to…”
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The Effect of C-Reactive Protein Isoforms on Nitric Oxide Production by U937 Monocytes/Macrophages by Sproston, Nicola R, El Mohtadi, Mohamed, Slevin, Mark, Gilmore, William, Ashworth, Jason J

“…Inflammation is regulated by many endogenous factors including estrogen, a steroid hormone that declines with increasing age, leading to excessive inflammation…”
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The hormonal regulation of cutaneous wound healing by Gilliver, Stephen C., PhD, Ashworth, Jason J., PhD, Ashcroft, Gillian S., MD

“…Abstract Conditions of impaired wound healing in the elderly are associated with substantial morbidity and mortality and impose a significant financial burden…”
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A Pilot Study Investigating the Influence of Glucagon-Like Peptide-1 Receptor Single Nucleotide Polymorphisms on Gastric Emptying Rate in Caucasian Men by Yau, Adora M W, McLaughlin, John, Maughan, Ronald J, Gilmore, William, Ashworth, Jason J, Evans, Gethin H

“…Gastric emptying rate in humans is subject to large individual variability, but previous research on the influence of genetics is scarce. Variation in the…”
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Androgens modulate the inflammatory response during acute wound healing by Gilliver, Stephen C, Ashworth, Jason J, Mills, Stuart J, Hardman, Matthew J, Ashcroft, Gillian S

“…Impaired wound healing states in the elderly lead to substantial morbidity and mortality, and a cost to the health services of over 9 billion dollars per…”
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Modulation of innate and adaptive immune responses by arabinoxylans by Fadel, Abdulmannan, Plunkett, Andrew, Li, Weili, Tessu Gyamfi, Vivian Elewosi, Nyaranga, Rosemarie Roma, Fadel, Fatma, Dakak, Suaad, Ranneh, Yazan, Salmon, Yasser, Ashworth, Jason J

“…Humans are exposed to harmful pathogens and a wide range of noxious substances every day. The immune system reacts to, and destroys, these pathogens and…”
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Closed-Loop, Multiobjective Optimization of Two-Dimensional Gas Chromatography/Mass Spectrometry for Serum Metabolomics by Dunn, Warwick B, Knowles, Joshua D, Broadhurst, David, Williams, Rebecca, Ashworth, Jason J, Cameron, Maureen, Kell, Douglas B

“…Metabolomics seeks to measure potentially all the metabolites in a biological sample, and consequently, we need to develop and optimize methods to increase…”
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Differential engulfment of Staphylococcus aureus and Pseudomonas aeruginosa by monocyte-derived macrophages is associated with altered phagocyte biochemistry and morphology by El Mohtadi, Mohamed, Pilkington, Lisa, Liauw, Christopher M, Ashworth, Jason J, Dempsey-Hibbert, Nina, Belboul, Amina, Whitehead, Kathryn A

“…Knowledge of changes in macrophages following bacterial engulfment is limited. U937-derived macrophages were incubated with Staphylococcus aureus or…”
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Arabinoxylans from rice bran and wheat immunomodulatory potentials: a review article by Fadel, Abdulmannan, Plunkett, Andrew, Li, Weili, Ranneh, Yazan, Tessu Gyamfi, Vivian Elewosi, Salmon, Yasser, Nyaranga, Rosemarie Roma, Ashworth, Jason

“…Purpose The purpose of this study is to discuss recent research on arabinoxylans from rice bran and wheat byproducts and their immunomodulatory potentials…”
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Ageing and wound healing by ASHCROFT, Gillian S, MILLS, Stuart J, ASHWORTH, Jason J

“…Cutaneous wound healing is a complex process encompassing a number of overlapping events including leukocyte recruitment, matrix deposition, epithelialization,…”
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The influence of angiotensin converting enzyme and bradykinin receptor B2 gene variants on voluntary fluid intake and fluid balance in healthy men during moderate-intensity exercise in the heat by Yau, Adora M W, Moss, Andrew D, James, Lewis John, Gilmore, William, Ashworth, Jason J, Evans, Gethin H

“…Angiotensin converting enzyme (ACE) and bradykinin receptor B2 (B2R) genetic variation may affect thirst because of effects on angiotensin II production and…”
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The Sex Steroid Precursor DHEA Accelerates Cutaneous Wound Healing Via the Estrogen Receptors by Mills, Stuart J., Ashworth, Jason J., Gilliver, Stephen C., Hardman, Matthew J., Ashcroft, Gillian S.

“…Age-related impaired wound healing states lead to substantial morbidity and cost, with treatment in the USA resulting in an expenditure of over $9 billion per…”
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Potential role of estrogens in wound healing by Ashcroft, Gillian S, Ashworth, Jason J

“…Estrogens play a vital role in the development of sexually dimorphic characteristics essential for reproduction. In recent years, insight has been gained into…”
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The dinucleotide (CA) repeat polymorphism of estrogen receptor beta but not the dinucleotide (TA) repeat polymorphism of estrogen receptor alpha is associated with venous ulceration by Ashworth, Jason J., Smyth, J. Vincent, Pendleton, Neil, Horan, Michael, Payton, Antony, Worthington, Jane, Ollier, William E., Ashcroft, Gillian S.

“…Venous ulcers are the predominant form of chronic wound in the elderly, accounting for around 70% of all cases. The steroid sex hormone estrogen plays a…”
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Characterization of Nitric Oxide Modulatory Activities of Alkaline-Extracted and Enzymatic-Modified Arabinoxylans from Corn Bran in Cultured Human Monocytes by Zhang, Zhengxiao, Smith, Christopher, Li, Weili, Ashworth, Jason

“…The ingestion of foods and food-derived substances that may mediate the immune system is widely studied. Evidence suggests cereal arabinoxylans (AXs) have…”
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CD105 (Endoglin): A Potential Anticancer Therapeutic Inhibits Mitogenesis and Map Kinase Pathway Activation by Liu, Donghui, Kumar, Shant, Ashworth, Jason, Ali, Kamela, Fadel, Abdulmannan, Guo, Baoqiang, Slevin, Mark

“…CD105 is highly expressed on human activated endothelial cells (ECs), is an important component of the TGF-β1 receptor complex and is essential for…”
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Improving the extractability of arabinoxylans and the molecular weight of wheat endosperm using extrusion processing by Fadel, Abdulmannan, Ashworth, Jason, Plunkett, Andrew, Mahmoud, Ayman M., Ranneh, Yazan, Li, Weili

“…Cereal derived arabinoxylans (AXs) are non-starch polysaccharides that have immunomodulatory activities. These activities are thought to be related to the low…”
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Regulation of inducible nitric oxide synthase by arabinoxylans with molecular characterisation from wheat flour in cultured human monocytes by Zhang, Zhengxiao, Smith, Christopher, Ashworth, Jason, Li, Weili

“…Summary The immunomodulatory activity of the arabinoxylans (AXs) extracts from cereal sources has been reported to impart health benefits in terms of immune…”
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