Search Results - "Ashwal, Stephen"

Improved long-term outcome after transient cerebral ischemia in aquaporin-4 knockout mice by Hirt, Lorenz, Fukuda, Andrew M, Ambadipudi, Kamalakar, Rashid, Faisil, Binder, Devin, Verkman, Alan, Ashwal, Stephen, Obenaus, Andre, Badaut, Jerome

“…A hallmark of stroke is water accumulation (edema) resulting from dysregulation of osmotic homeostasis. Brain edema contributes to tissue demise and may lead…”
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Impaired neurovascular unit function contributes to persistent symptoms after concussion: a pilot study by Bartnik-Olson, Brenda L, Holshouser, Barbara, Wang, Harrison, Grube, Matthew, Tong, Karen, Wong, Valarie, Ashwal, Stephen

“…Research shows that approximately 14% of school age children with mild traumatic brain injury (TBI) including sports-related concussions (SRCs) remain…”
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Animal Models of Perinatal Hypoxic-Ischemic Brain Damage by Yager, Jerome Y., MD, Ashwal, Stephen, MD

“…Animal models are often presumably the first step in determining mechanisms underlying disease, and the approach and effectiveness of therapeutic…”
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Brain water mobility decreases after astrocytic aquaporin-4 inhibition using RNA interference by Badaut, Jérôme, Ashwal, Stephen, Adami, Arash, Tone, Beatriz, Recker, Rebecca, Spagnoli, David, Ternon, Béatrice, Obenaus, Andre

“…Neuroimaging with diffusion-weighted imaging is routinely used for clinical diagnosis/prognosis. Its quantitative parameter, the apparent diffusion coefficient…”
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Multicenter phase 2 trial of sirolimus for tuberous sclerosis: kidney angiomyolipomas and other tumors regress and VEGF- D levels decrease by Dabora, Sandra L, Franz, David Neal, Ashwal, Stephen, Sagalowsky, Arthur, DiMario, Jr, Francis J, Miles, Daniel, Cutler, Drew, Krueger, Darcy, Uppot, Raul N, Rabenou, Rahmin, Camposano, Susana, Paolini, Jan, Fennessy, Fiona, Lee, Nancy, Woodrum, Chelsey, Manola, Judith, Garber, Judy, Thiele, Elizabeth A

“…Tuberous sclerosis (TSC) related tumors are characterized by constitutively activated mTOR signaling due to mutations in TSC1 or TSC2. We completed a phase 2…”
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Patterns of brain injury in term neonatal encephalopathy by Miller, Steven P., Ramaswamy, Vijay, Michelson, David, Barkovich, A. James, Holshouser, Barbara, Wycliffe, Nathaniel, Glidden, David V., Deming, Douglas, Partridge, J. Colin, Wu, Yvonne W., Ashwal, Stephen, Ferriero, Donna M.

“…To determine whether the pattern of brain injury in term neonatal encephalopathy is associated with distinct prenatal and perinatal factors and to determine…”
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Guidelines for the determination of brain death in infants and children: An update of the 1987 Task Force recommendations by Nakagawa, Thomas A, Ashwal, Stephen, Mathur, Mudit, Mysore, Mohan R, Bruce, Derek, Conway, Edward E, Duthie, Susan E, Hamrick, Shannon, Harrison, Rick, Kline, Andrea M, Lebovitz, Daniel J, Madden, Maureen A, Montgomery, Vicki L, Perlman, Jeffrey M, Rollins, Nancy, Shemie, Sam D, Vohra, Amit, Williams-Phillips, Jacqueline A

“…OBJECTIVE:To review and revise the 1987 pediatric brain death guidelines. METHODS:Relevant literature was reviewed. Recommendations were developed using the…”
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White Matter Metabolite Ratios Predict Cognitive Outcome in Pediatric Traumatic Brain Injury by Berger, Luke, Holshouser, Barbara, Nichols, Joy G, Pivonka-Jones, Jamie, Ashwal, Stephen, Bartnik-Olson, Brenda

“…The prognostic ability of global white matter and gray matter metabolite ratios following pediatric traumatic brain injury (TBI) and their relationship to…”
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Predicting outcomes of traumatic brain injury by imaging modality and injury distribution by Chastain, Cody A, Oyoyo, Udochukwu E, Zipperman, Michelle, Joo, Elliot, Ashwal, Stephen, Shutter, Lori A, Tong, Karen A

“…Early prediction of outcomes after traumatic brain injury (TBI) is often difficult. To improve prognostic accuracy soon after trauma, we compared different…”
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Antithrombotic Treatment in Neonatal Cerebral Sinovenous Thrombosis: Results of the International Pediatric Stroke Study by Jordan, Lori C., MD, PhD, Rafay, Mubeen F., MB, BS, MSc, Smith, Sabrina E., MD, PhD, Askalan, Rand, PhD, MD, Zamel, Khaled M., MBChB, deVeber, Gabrielle, MD, MHSc, Ashwal, Stephen, MD

“…Objective To identify predictors of antithrombotic treatment in neonates with cerebral sinovenous thrombosis (CSVT) in a large multinational study. Study…”
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Cosyntropin Attenuates Neuroinflammation in a Mouse Model of Traumatic Brain Injury by Siebold, Lorraine, Krueger, Amy C., Abdala, Jonathan A., Figueroa, Johnny D., Bartnik-Olson, Brenda, Holshouser, Barbara, Wilson, Christopher G., Ashwal, Stephen

“…Aim: Traumatic brain injury (TBI) is a leading cause of mortality/morbidity and is associated with chronic neuroinflammation. Melanocortin receptor agonists…”
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Oral Sucrose for Heel Lance Increases Adenosine Triphosphate Use and Oxidative Stress in Preterm Neonates by Asmerom, Yayesh, MS, Slater, Laurel, BSN, RNC, Boskovic, Danilo S., PhD, Bahjri, Khaled, MD, Holden, Megan S., BS, Phillips, Raylene, MD, Deming, Douglas, MD, Ashwal, Stephen, MD, Fayard, Elba, MD, Angeles, Danilyn M., PhD

“…Objective To examine the effects of sucrose on pain and biochemical markers of adenosine triphosphate (ATP) degradation and oxidative stress in preterm…”
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Temporal and regional evolution of aquaporin-4 expression and magnetic resonance imaging in a rat pup model of neonatal stroke by BADAUT, Jérome, ASHWAL, Stephen, TONE, Beatriz, REGLI, Luca, HOU ROU TIAN, OBENAUS, Andre

“…Edema formation can be observed using magnetic resonance imaging (MRI) in patients with stroke. Recent studies have shown that aquaporin-4 (AQP4), a water…”
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Child Neurology Practice Guidelines: Past, Present, and Future by Hurwitz, Benjamin A., MS, Hurwitz, Kathleen Bretzius, MD, Ashwal, Stephen, MD

“…Abstract Background Practice guidelines have been developed in child neurology during the last fifteen years to address important clinical questions and…”
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Comparison of two neonatal ischemic injury models using magnetic resonance imaging by ASHWAL, Stephen, TONE, Beatriz, HUI ROU TIAN, CHONG, Samuel, OBENAUS, Andre

“…Using an 11.7-Tesla magnetic resonance imaging (MRI) scanner in 10-d-old rat pups we report on the evolution of injury over 28 d in a model of neonatal stroke…”
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Evaluation of the Child With Acute Ataxia: A Systematic Review by Whelan, Harry T., MD, Verma, Sumit, MD, Guo, Yan, MD, PhD, Thabet, Farouq, MD, Bozarth, Xiuhua, MD, PhD, Nwosu, Michelle, MBBS, Katyayan, Akshat, MD, Parachuri, Venu, MD, Spangler, Katie, MD, Ruggeri, Barbara E., MLIS, Srivatsal, Sindhu, MD, Zhang, Guojun, MD, PhD, Ashwal, Stephen, MD

“…Abstract Evaluation of acute ataxia in a child poses a dilemma for the clinician in determining the extent and timing of initial screening tests. This article…”
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Susceptibility Weighted Imaging: Neuropsychologic Outcome and Pediatric Head Injury by Babikian, Talin, Freier, M. Catherin, Tong, Karen A., Nickerson, Joshua P., Wall, Christopher J., Holshouser, Barbara A., Burley, Todd, Riggs, Matt L., Ashwal, Stephen

“…Traumatic brain injury is among the most frequent pediatric neurologic disorders in the United States, affecting multiple aspects of neuropsychologic…”
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Variability in Pediatric Brain Death Determination and Documentation in Southern California by Mathur, Mudit, Petersen, LuCyndi, Stadtler, Maria, Rose, Colleen, Ejike, J. Chiaka, Petersen, Floyd, Tinsley, Cynthia, Ashwal, Stephen

“…Because the concept of brain death is difficult to define and to apply, we hypothesized that significant variability exists in pediatric brain death…”
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Guidelines for the Determination of Brain Death in Infants and Children: An Update of the 1987 Task Force Recommendations by Nakagawa, Thomas A., Ashwal, Stephen, Mathur, Mudit, Mysore, Mohan

“…This Clinical Report was retired October 2023. OBJECTIVE: To review and revise the 1987 pediatric brain death guidelines. METHODS: Relevant literature was…”
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Multimodality Comparison of Neuroimaging in Pediatric Traumatic Brain Injury by Sigmund, Geoffrey A, Tong, Karen A., MD, Nickerson, Joshua P., MD, Wall, Christopher J., MD, Oyoyo, Udo, Ashwal, Stephen, MD

“…Traumatic brain injury is a common cause of death and disability in children; early neuroimaging has assumed an increasingly important role in evaluating the…”
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