Search Results - "Ashton, Edward"

Repeatability of MR Elastography of Liver: A Meta-Analysis by Serai, Suraj D, Obuchowski, Nancy A, Venkatesh, Sudhakar K, Sirlin, Claude B, Miller, Frank H, Ashton, Edward, Cole, Patricia E, Ehman, Richard L

“…Purpose To perform a meta-analysis to generate an estimate of the repeatability coefficient (RC) for magnetic resonance (MR) elastography of the liver…”
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FOSSIL. III. Lightcurves of 371 Trans-Neptunian Objects by Ashton, Edward, Chang, Chan-Kao, Chen, Ying-Tung, Lehner, Matthew J., Wang, Shiang-Yu, Alexandersen, Mike, Choi, Young-Jun, Fraser, Wesley C., Granados Contreras, A. Paula, Ito, Takashi, JeongAhn, Youngmin, Ji, Jianghui, Kavelaars, JJ, Kim, Myung-Jin, Lawler, Samantha M., Li, Jian, Lin, Zhong-Yi, Lykawka, Patryk Sofia, Moon, Hong-Kyu, More, Surhud, Muñoz-Gutiérrez, Marco A., Ohtsuki, Keiji, Pike, Rosemary E., Terai, Tsuyoshi, Urakawa, Seitaro, Yoshida, Fumi, Zhang, Hui, Zhao, Haibin, Zhou, Ji-Lin

“…From the first phase of the high-cadence Formation of the Outer Solar System: an Icy Legacy (FOSSIL) survey, we analyzed lightcurves, ranging from one to four…”
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Dynamic Contrast-Enhanced Magnetic Resonance Imaging As a Pharmacodynamic Measure of Response After Acute Dosing of AG-013736, an Oral Angiogenesis Inhibitor, in Patients With Advanced Solid Tumors: Results From a Phase I Study by LIU, Glenn, RUGO, Hope S, CHARNSANGAVEJ, Chusilp, PARK, John W, ASHTON, Edward A, STEINFELDT, Heidi M, PITHAVALA, Yazdi K, REICH, Steven D, HERBST, Roy S, WILDING, George, MCSHANE, Teresa M, EVELHOCH, Jeffrey L, NG, Chaan, JACKSON, Edward, KELCZ, Frederick, YEH, Benjamin M, LEE, Fred T

“…Identifying suitable markers of biologic activity is important when assessing novel compounds such as angiogenesis inhibitors to optimize the dose and schedule…”
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Reproducibility of Perfusion Parameters in Dynamic Contrast-Enhanced MRI of Lung and Liver Tumors: Effect on Estimates of Patient Sample Size in Clinical Trials and on Individual Patient Responses by Ng, Chaan S, Raunig, David L, Jackson, Edward F, Ashton, Edward A, Kelcz, Frederick, Kim, Kevin B, Kurzrock, Razelle, McShane, Teresa M

“…Dynamic contrast-enhanced MRI (DCE-MRI) is a potentially useful noninvasive technique for assessing tissue perfusion, particularly in the context of solid…”
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Magnetic resonance imaging of the hand and wrist in a randomized, double-blind, multicenter, placebo-controlled trial of infliximab for rheumatoid arthritis: Comparison of dynamic contrast enhanced assessments with semi-quantitative scoring by Beals, Chan, Baumgartner, Richard, Peterfy, Charles, Balanescu, Andra, Mirea, Gavrila, Harabagiu, Alexandru, Popa, Serghei, Cheng, Amy, Feng, Dai, Ashton, Edward, DiCarlo, Julie, Vallee, Marie-Helene, Dardzinski, Bernard J

“…The objective of this study was to compare the scope and the discriminative power of Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) to those of…”
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Efficacy, Safety, and Potential Biomarkers of Sunitinib and Transarterial Chemoembolization (TACE) Combination in Advanced Hepatocellular Carcinoma (HCC): Phase II Trial by Pokuri, Venkata K, Tomaszewski, Garin M, Ait-Oudhia, Sihem, Groman, Adrienne, Khushalani, Nikhil I, Lugade, Amit A, Thanavala, Yasmin, Ashton, Edward A, Grande, Catherine, Fetterly, Gerald J, Iyer, Renuka

“…To evaluate the safety/efficacy and explore biomarkers for a rationally designed combination of sunitinib and transarterial chemoembolization (TACE) in a…”
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A phase I study of MN-029 (denibulin), a novel vascular-disrupting agent, in patients with advanced solid tumors by Ricart, Alejandro D., Ashton, Edward A., Cooney, Matthew M., Sarantopoulos, John, Brell, Joanna M., Feldman, Maria A., Ruby, Kale E., Matsuda, Kazuko, Munsey, Mark S., Medina, Gerardo, Zambito, Angela, Tolcher, Anthony W., Remick, Scot C.

“…Purpose MN-029 (denibulin HCl) is a novel vascular-disrupting agent that reversibly inhibits microtubule assembly, resulting in disruption of the cytoskeleton…”
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Accuracy and reproducibility of manual and semiautomated quantification of MS lesions by MRI by Ashton, Edward A., Takahashi, Chihiro, Berg, Michel J., Goodman, Andrew, Totterman, Saara, Ekholm, Sven

“…Purpose To evaluate the accuracy, reproducibility, and speed of two semiautomated methods for quantifying total white matter lesion burden in multiple…”
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Detection of subpixel anomalies in multispectral infrared imagery using an adaptive Bayesian classifier by Ashton, E.A.

“…The detection of subpixel targets with unknown spectral signatures and cluttered backgrounds in multispectral imagery is a topic of great interest for remote…”
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Quantitative MR in multi-center clinical trials by Ashton, Edward

“…MRI has a wide variety of applications in the clinical trials process. MR has shown particular utility in the early phases of clinical development, when trial…”
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Advanced MR techniques in multicenter clinical trials by Ashton, Edward, Riek, Jonathan

“…MRI has had a place in the clinical trials process for more than 20 years. However, for much of that time MRI has been used primarily for subjective…”
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Evidence for a Recent Collision in Saturn’s Irregular Moon Population by Ashton, Edward, Gladman, Brett, Beaudoin, Matthew

“…Using CFHT imaging data, we searched a 1.1 deg 2 field on each side of Saturn down to magnitude m w ≃ 26.3, corresponding to diameters of D ≃ 3 km. We detected…”
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The Population of Kilometer-scale Retrograde Jovian Irregular Moons by Ashton, Edward, Beaudoin, Matthew, Gladman, Brett J.

“…We have searched a 2010 archival data set from the Canada–France–Hawaii Telescope for very small (km-scale) irregular moons of Jupiter in order to constrain…”
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A novel volumetric feature extraction technique with applications to MR images by Ashton, E.A., Parker, K.J., Berg, M.J., Chang Wen Chen

“…A semiautomated feature extraction algorithm is presented for the extraction and measurement of the hippocampus from volumetric magnetic resonance imaging…”
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OSSOS. XVII. An upper limit on the number of distant planetary objects in the Solar System by Ashton, Edward, Gladman, Brett, Kavelaars, J.J., Jones, R. Lynne, Krughoff, K. Simon, Alexandersen, Mike, Bannister, Michele T., Chen, Ying-Tung, Gwyn, Stephen, Petit, Jean-Marc, Volk, Kathryn

“…Beyond the giant planets there is a collection of bodies left over from the epoch of planet formation. The objects that are just beyond Neptune are more easily…”
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Discovery of the Closest Saturnian Irregular Moon, S/2019 S 1, and Implications for the Direct/Retrograde Satellite Ratio by Ashton, Edward, Gladman, Brett, Beaudoin, Matthew, Alexandersen, Mike, Petit, Jean-Marc

“…We present a tracked orbit for a recently discovered 25th magnitude irregular moon of Saturn, using Canada-France-Hawaii Telescope imaging. Our 2 yr of…”
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Scan-rescan variability in perfusion assessment of tumors in MRI using both model and data-derived arterial input functions by Ashton, Edward, Raunig, David, Ng, Chaan, Kelcz, Fredrick, McShane, Teresa, Evelhoch, Jeffrey

“…Purpose To evaluate the contribution to scan‐rescan coefficient of variation (CV) of patient‐specific arterial input function (AIF) measurement in dynamic…”
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Phase 1 First-in-Human Trial of the Vascular Disrupting Agent Plinabulin (NPI-2358) in Patients with Solid Tumors or Lymphomas by MITA, Monica M, SPEAR, Matthew A, PILAT, Maryjo, LLOYD, G. Kenneth, NEUTEBOOM, Saskia T. C, CROPP, Gillian, ASHTON, Edward, LORUSSO, Patricia M, YEE, Lorrin K, MITA, Alain C, HEATH, Elisabeth I, PAPADOPOULOS, Kyriakos P, FEDERICO, Kristine C, REICH, Steven D, ROMERO, Ofelia, MALBURG, Lisa

“…Plinabulin (NPI-2358) is a vascular disrupting agent that elicits tumor vascular endothelial architectural destabilization leading to selective collapse of…”
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Abstract 4946: Developing anti-angiogenic therapies for human hepatocellular cancer (HCC)- studies of suntinib in the woodchuck model of hepatitis B related HCC by Pomakov, Alexander, Toshkov, Ilia, Buitrago, Sandra, Curtin, Leslie, Trump, Donald, Johnson, Candace, Ashton, Edward, Tennant, Bud, Iyer, Renuka

“…Introduction: Better animal models that recapitulate the liver milieu of human HCC are needed. The eastern woodchuck is an established model of human hepatitis…”
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Mo1927 Histological Changes Following Sunitinib Therapy in the Woodchuck Model of Hepatitis B Related HCC by Pomakov, Alexander, Toshkov, Ilia, Buitrago, Sandra, Curtin, Leslie, Trump, Donald, Johnson, Candace S, Ashton, Edward, Tennant, Bud, Iyer, Renuka

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