Search Results - "Ashton, A W"

Processing two‐dimensional X‐ray diffraction and small‐angle scattering data in DAWN 2 by Filik, J., Ashton, A. W., Chang, P. C. Y., Chater, P. A., Day, S. J., Drakopoulos, M., Gerring, M. W., Hart, M. L., Magdysyuk, O. V., Michalik, S., Smith, A., Tang, C. C., Terrill, N. J., Wharmby, M. T., Wilhelm, H.

“…A software package for the calibration and processing of powder X‐ray diffraction and small‐angle X‐ray scattering data is presented. It provides a multitude…”
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SynchWeb: a modern interface for ISPyB by Fisher, S. J., Levik, K. E., Williams, M. A., Ashton, A. W., McAuley, K. E.

“…SynchWeb is a modern interface to the ISPyB database. It significantly simplifies sample registration and is targeted towards live data collection monitoring…”
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First trimester screening of maternal placental protein 13 for predicting preeclampsia and small for gestational age: In-house study and systematic review by Schneuer, F.J, Nassar, N, Khambalia, A.Z, Tasevski, V, Ashton, A.W, Morris, J.M, Roberts, C.L

“…Abstract Objective To describe normative levels of PP13 in first trimester of pregnancy and determine the accuracy of PP13 in predicting preeclampsia and small…”
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ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance by Mercier, I, Vuolo, M, Madan, R, Xue, X, Levalley, A J, Ashton, A W, Jasmin, J-F, Czaja, M T, Lin, E Y, Armstrong, R C, Pollard, J W, Kitsis, R N

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Ongoing developments in CCP4 for high-throughput structure determination by Winn, M. D., Ashton, A. W., Briggs, P. J., Ballard, C. C., Patel, P.

“…Collaborative Computational Project Number 4 (CCP4) was established in 1979 to promote collaboration between UK groups writing software for protein…”
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The new CCP4 Coordinate Library as a toolkit for the design of coordinate-related applications in protein crystallography by Krissinel, E. B., Winn, M. D., Ballard, C. C., Ashton, A. W., Patel, P., Potterton, E. A., McNicholas, S. J., Cowtan, K. D., Emsley, P.

“…The new CCP4 Coordinate Library is a development aiming to provide a common layer of coordinate‐related functionality to the existing applications in the CCP4…”
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Using Scipion for stream image processing at Cryo-EM facilities by Gómez-Blanco, J., de la Rosa-Trevín, J.M., Marabini, R., del Cano, L., Jiménez, A., Martínez, M., Melero, R., Majtner, T., Maluenda, D., Mota, J., Rancel, Y., Ramírez-Aportela, E, Vilas, J.L., Carroni, M., Fleischmann, S., Lindahl, E., Ashton, A.W., Basham, M., Clare, D.K., Savage, K., Siebert, C.A., Sharov, G.G., Sorzano, C.O.S., Conesa, P., Carazo, J.M.

“…Three dimensional electron microscopy is becoming a very data-intensive field in which vast amounts of experimental images are acquired at high speed. To…”
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Source of angiopoietin-2 in the sera of women during pregnancy by Woolnough, C., Wang, Y., Kan, C.Y., Morris, J.M., Tasevski, V., Ashton, A.W.

“…Placental development requires coordinated angiogenesis regulated by multiple factors including angiopoietins. Previously we demonstrated that the…”
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Molecular structures from low angle X-ray and neutron scattering studies by Perkins, S.J, Ashton, A.W, Boehm, M.K, Chamberlain, D

“…Molecular structures can be extracted from solution scattering analyses of multidomain or oligomeric proteins by a new method of constrained automated…”
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Effects of gender and gender role identification of participant and type of social support resource on support seeking by ASHTON, W. A, FUEHRER, A

“…The relationship between type of social support resource (emotional vs instrumental support) sought and gender and gender role identification was examined. In…”
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Regulation of Connexin43 Protein Complexes by Intracellular Acidification by Duffy, Heather S, Ashton, Anthony W, O’Donnell, Phyllis, Coombs, Wanda, Taffet, Steve M, Delmar, Mario, Spray, David C

“…ABSTRACT—Ischemia-induced acidification of astrocytes or cardiac myocytes reduces intercellular communication by closing gap junction channels and subsequently…”
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Fibroblast Growth Factor-2 Induces Lef/Tcf-dependent Transcription in Human Endothelial Cells by Holnthoner, Wolfgang, Pillinger, Manuela, Groger, Marion, Wolff, Klaus, Ashton, Anthony W, Albanese, Chris, Neumeister, Peter, Pestell, Richard G, Petzelbauer, Peter

“…Lef/Tcf proteins belong to a family of architectural transcription factors that control developmental processes and play an important role in oncogenesis…”
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Inhibition of endothelial cell migration, intercellular communication, and vascular tube formation by thromboxane A(2) by Ashton, A W, Yokota, R, John, G, Zhao, S, Suadicani, S O, Spray, D C, Ware, J A

“…The eicosanoid thromboxane A(2) (TXA(2)) is released by activated platelets, monocytes, and the vessel wall and interacts with high affinity receptors…”
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Reversal of angiogenesis in vitro, induction of apoptosis, and inhibition of AKT phosphorylation in endothelial cells by thromboxane A(2) by Gao, Y, Yokota, R, Tang, S, Ashton, A W, Ware, J A

“…Thromboxane A(2) (TxA(2)) causes platelet aggregation, vasoconstriction, and inhibition of endothelial cell (EC) migration and prevents vascular tube formation…”
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Inhibition of Tumor Necrosis Factor α-mediated NFκB Activation and Leukocyte Adhesion, with Enhanced Endothelial Apoptosis, by G Protein-linked Receptor (TP) Ligands by Ashton, Anthony W., Ware, Gabriel M., Kaul, Dhananjaya K., Ware, J. Anthony

“…Tumor necrosis factor (TNF) alpha is a critical mediator of inflammation; however, TNF alpha is rarely released alone and the "cross-talk" between different…”
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Mechanisms of Hepatocyte Growth Factor–Mediated Vascular Smooth Muscle Cell Migration by Ma, Harry, Calderon, Tina M, Kessel, Tamar, Ashton, Anthony W, Berman, Joan W

“…ABSTRACT—The migration of vascular smooth muscle cells (SMCs) from the media into the neointima and their subsequent proliferation is important in the…”
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Pentameric and decameric structures in solution of serum amyloid P component by X-ray and neutron scattering and molecular modelling analyses by Ashton, A W, Boehm, M K, Gallimore, J R, Pepys, M B, Perkins, S J

“…Human serum amyloid P component (SAP) is a normal plasma glycoprotein and the precursor of amyloid P component which is a universal constituent of the abnormal…”
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A57 LUNG INJURY, REPAIR, AND FIBROSIS: THE PLOT THICKENS FOR THREE'S COMPANY: Investigating Differences In The Composition And Angiogenic Potential Of The Ecm Deposited By Asthmatic And Non-Asthmatic Asm Cells Under Quiescing Conditions by Harkness, L M, Ashton, A W, Burgess, J K

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A18 FRESH PERSPECTIVES ON AIRWAY REMODELING AND AIRWAY HYPERRESPONSIVENESS: Tumstatin Regulates The Composition And Angiogenic Properties Of The Airway Ecm by Harkness, L M, Ashton, A W, Burgess, J K

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The Solution Structure of Human Coagulation Factor VIIa in Its Complex with Tissue Factor Is Similar to Free Factor VIIa:  A Study of a Heterodimeric Receptor−Ligand Complex by X-ray and Neutron Scattering and Computational Modeling by Ashton, Alun W, Boehm, Mark K, Johnson, Daniel J. D, Kemball-Cook, Geoffrey, Perkins, Stephen J

“…Factor VIIa (FVIIa) is a soluble four-domain plasma serine protease coagulation factor that forms a tight complex with the two extracellular domains of the…”
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