Search Results - "Ashry, Tameem"
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1
Anti‐PD‐1/PD‐L1 therapy augments lenvatinib's efficacy by favorably altering the immune microenvironment of murine anaplastic thyroid cancer
Published in International journal of cancer (01-05-2019)“…Patients with anaplastic thyroid cancer (ATC) have an extremely poor prognosis despite multimodal therapy with surgery and chemoradiation. Lenvatinib, a…”
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Journal Article -
2
Mast cells, cortistatin, and its receptor, MRGPRX2, are linked to the pathogenesis of chronic prurigo
Published in Journal of allergy and clinical immunology (01-06-2022)“…Chronic prurigo (CPG) is characterized by intensive itch and interactions among nerves, neuropeptides, and mast cells (MCs). The role of some neuropeptides…”
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Journal Article -
3
The Number of MRGPRX2-Expressing Cells Is Increased in Skin Lesions of Patients With Indolent Systemic Mastocytosis, But Is Not Linked to Symptom Severity
Published in Frontiers in immunology (26-07-2022)“…BackgroundRecently, the expression of the mast cell (MC) receptor Mas-related G protein-coupled receptor X2 (MRGPRX2) has been detected in lesional skin of…”
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Journal Article -
4
Combinations of BRAF inhibitor and anti-PD-1/PD-L1 antibody improve survival and tumour immunity in an immunocompetent model of orthotopic murine anaplastic thyroid cancer
Published in British journal of cancer (13-11-2018)“…Background Patients with anaplastic thyroid cancer (ATC) have an extremely poor prognosis despite aggressive multimodal therapy. ATC has a high prevalence of…”
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Journal Article -
5
Novel intragraft regulatory lymphoid structures in kidney allograft tolerance
Published in American journal of transplantation (01-03-2022)“…Intragraft events thought to be relevant to the development of tolerance are here subjected to a comprehensive mechanistic study during long‐term spontaneous…”
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Journal Article -
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Treg-Rich Organized Lymphoid Structures that Develop in Spontaneously Accepted Murine Renal Allografts Have Thymic-Like Characteristics
Published 01-01-2017“…Introduction: Novel lymphoid structures identified within the parenchyma of kidney allografts are associated with the induction of spontaneous or active immune…”
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Dissertation