Search Results - "Ashrafi, Nadia"
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Metabolomics: An Emerging "Omics" Platform for Systems Biology and Its Implications for Huntington Disease Research
Published in Metabolites (01-12-2023)“…Huntington's disease (HD) is a progressive, fatal neurodegenerative disease characterized by motor, cognitive, and psychiatric symptoms. The precise mechanisms…”
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Associations between Lifestyle Factors and Vitamin E Metabolites in the General Population
Published in Antioxidants (15-12-2020)“…The antioxidant vitamin E (α-tocopherol, α-TOH) protects lipids from oxidation by reactive oxygen species. We hypothesized that lifestyle factors associate…”
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Case studies: Effects of beef, whey and carbohydrate supplementation in female master triathletes
Published in Journal of human sport and exercise (01-01-2019)“…Appropriate nutritional supplementation is crucial for athletic performance, particularly for female endurance athletes as their numbers steadily increase…”
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Maternal saliva metabolomics: the prediction and pathogenesis of fetal isolated congenital heart defect
Published in American journal of obstetrics and gynecology (01-01-2023)Get full text
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127 Effects of maternal pre- and post-partum supplementation of a Bacillus -based DFM on plasma metabolome profile of Bos indicus -influenced heifers and their offspring
Published in Journal of animal science (14-09-2024)“…Abstract This study evaluated the effects of maternal supplementation during pre- and postpartum of a Bacillus-based direct-fed microbial (DFM) on plasma…”
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Fetal Effects of COVID-19 Infection: Targeted Metabolomic profiling of cord blood
Published in American journal of obstetrics and gynecology (01-01-2022)Get full text
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Precision Medicine in Preeclampsia: Metabolomic and Lipidomic investigation of disease mechanisms
Published in American journal of obstetrics and gynecology (01-01-2022)Get full text
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Effects of protein–carbohydrate supplementation on immunity and resistance training outcomes: a double-blind, randomized, controlled clinical trial
Published in European journal of applied physiology (01-02-2017)“…Purpose To examine the impact of ingesting hydrolyzed beef protein, whey protein, and carbohydrate on resistance training outcomes, body composition, muscle…”
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Metabolomic prediction of severe maternal and newborn complications in preeclampsia
Published in Metabolomics (18-05-2024)“…Introduction Preeclampsia (PreE) remains a major source of maternal and newborn complications. Prenatal prediction of these complications could significantly…”
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Pre-estrus progesterone does not affect post-estrus luminal metabolome in cross-bred beef cows
Published in Reproduction (Cambridge, England) (01-08-2023)“…The concentration of progesterone through the estrous cycle modulates uterine function to affect the luminal metabolome. This paper reports that the dynamic…”
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Induced endometrial inflammation compromises conceptus development in dairy cattle
Published in Biology of reproduction (13-10-2023)“…Endometrial inflammation is associated with reduced pregnancy per artificial insemination (AI) and increased pregnancy loss in cows. It was hypothesized that…”
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Fetal effects of mild maternal COVID-19 infection: metabolomic profiling of cord blood
Published in Metabolomics (15-04-2023)“…Introduction The impact of maternal coronavirus disease 2019 (COVID-19) infection on fetal health remains to be precisely characterized. Objectives Using…”
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Associations of metabolomic profiles with circulating vitamin E and urinary vitamin E metabolites in middle-aged individuals
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-01-2022)“…•Lipoproteins are involved in the vascular transportation of α-tocopherol.•α-Tocopherol is catabolized in the liver or oxidized in the periphery.•Metabolomic…”
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Urinary oxidized, but not enzymatic vitamin E metabolites are inversely associated with measures of glucose homeostasis in middle-aged healthy individuals
Published in Clinical nutrition (Edinburgh, Scotland) (01-06-2021)“…Damage induced by lipid peroxidation has been associated with impaired glucose homeostasis. Vitamin E (α-tocopherol, α-TOH) competitively reacts with lipid…”
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Sex- and age-associated factors drive the pathophysiology of MASLD
Published in Hepatology communications (01-09-2024)“…Metabolic dysfunction-associated steatotic liver disease (MASLD) is strongly associated with obesity. Sex and age affect MASLD prevalence and pathophysiology…”
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Association of measures of body fat with serum alpha-tocopherol and its metabolites in middle-aged individuals
Published in Nutrition, metabolism, and cardiovascular diseases (22-07-2021)“…The accumulation of fat increases the formation of lipid peroxides, which are partly scavenged by alpha-tocopherol (α-TOH). Here, we aimed to investigate the…”
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Detection of human salivary α-defensins by LC-ESI-MS and evaluation of levels in athletes after physical stress
Published 01-01-2017“…The aim of this study was to optimise and validate an LC-ESI-MS method to determine the level of individual human neutrophil alpha defensins (HNP1-4) after…”
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Proteomic Analysis of the Myocardium in Hypertrophic Obstructive Cardiomyopathy
Published in Circulation. Genomic and precision medicine (01-12-2018)“…Background: Hypertrophic cardiomyopathy (HCM) is characterized by a complex phenotype that is only partly explained by the biological effects of individual…”
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