Search Results - "Ashrafi, G Hossein"

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  1. 1

    Synergistic effects of various Her inhibitors in combination with IGF-1R, C-MET and Src targeting agents in breast cancer cell lines by Stanley, Aryan, Ashrafi, G. Hossein, Seddon, Alan M., Modjtahedi, Helmout

    Published in Scientific reports (21-06-2017)
    “…Overexpression of HER2 has been reported in around 25% of human breast cancers. Despite recent advances in HER2 targeted therapy, many patients still…”
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    Ficus carica Latex Modulates Immunity-Linked Gene Expression in Human Papillomavirus Positive Cervical Cancer Cell Lines: Evidence from RNA Seq Transcriptome Analysis by Cakir, Muharrem Okan, Bilge, Ugur, Naughton, Declan, Ashrafi, G. Hossein

    “…Cervical carcinogenesis is the leading cause of cancer-related deaths in women, and the role of high-risk human papillomavirus (HR-HPV) as a possible risk…”
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    Biological activities of Ficus carica latex for potential therapeutics in Human Papillomavirus (HPV) related cervical cancers by Ghanbari, Arshia, Le Gresley, Adam, Naughton, Declan, Kuhnert, Nikolai, Sirbu, Diana, Ashrafi, G. Hossein

    Published in Scientific reports (31-01-2019)
    “…Infection caused by high-risk human papillomaviruses (HPVs) are implicated in the aetiology of cervical cancer. Although current methods of treatment for…”
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    Regulatory Effect of Ficus carica Latex on Cell Cycle Progression in Human Papillomavirus-Positive Cervical Cancer Cell Lines: Insights from Gene Expression Analysis by Cakir, Muharrem Okan, Bilge, Ugur, Ghanbari, Arshia, Ashrafi, G Hossein

    Published in Pharmaceuticals (Basel, Switzerland) (12-12-2023)
    “…Cervical cancer presents a significant global health concern with high-risk human papillomaviruses (HPVs) identified as the main cause of this cancer. Although…”
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    Detection of high-risk Human Papillomavirus in prostate cancer from a UK based population by Ahmed, M. Yahya, Salman, Nadia Aziz, Sandhu, Sarbjinder, Cakir, M. Okan, Seddon, Alan M., Kuehne, Christian, Ashrafi, G. Hossein

    Published in Scientific reports (10-05-2023)
    “…Human papillomavirus (HPV) infection is one of the sexually transmitted diseases which have been implicated in the etiology of multiple cancers. To date,…”
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    Concurrent high risk HPV35, HPV45, and HPV59 infections in prostate and bladder cancer tissues of a single patient: A case report by Ahmed, M. Yahya, Cakir, Muharrem Okan, Salman, Nadia Aziz, Sandhu, Sarbjinder, Ashrafi, G. Hossein

    Published in Heliyon (15-08-2024)
    “…Human papillomavirus (HPV) infections, primarily transmitted through sexual contact, have been linked to various cancers, including cervical, penile, anal,…”
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    All 4 di‐leucine motifs in the first hydrophobic domain of the E5 oncoprotein of human papillomavirus type 16 are essential for surface MHC class I downregulation activity and E5 endomembrane localization by Cortese, Marc S., Ashrafi, G. Hossein, Campo, M. Saveria

    Published in International journal of cancer (01-04-2010)
    “…The E5 oncoprotein of human papillomavirus type 16 downregulates surface MHC Class I and interacts with the heavy chain of the MHC complex via the first…”
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    E5 protein of human papillomavirus 16 downregulates HLA class I and interacts with the heavy chain via its first hydrophobic domain by Ashrafi, G. Hossein, Haghshenas, Mohammad, Marchetti, Barbara, Campo, M. Saveria

    Published in International journal of cancer (01-11-2006)
    “…Human papillomavirus type 16 E5 protein (HPV‐16 E5) is expressed early in papillomavirus infection and is localised primarily in the cell Golgi apparatus (GA)…”
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    E5 protein of human papillomavirus type 16 selectively downregulates surface HLA class I by Ashrafi, G. Hossein, Haghshenas, Mohammad R., Marchetti, Barbara, O'Brien, Philippa M., Campo, M. Saveria

    Published in International journal of cancer (10-01-2005)
    “…Papillomaviruses have evolved mechanisms that result in escape from host immune surveillance. The E5 protein is expressed early in papillomavirus infection in…”
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    Effects of human papillomavirus type 16 E5 deletion mutants on epithelial morphology: functional characterization of each transmembrane domain by Barbaresi, Silvia, Cortese, Marc S, Quinn, Jean, Ashrafi, G. Hossein, Graham, Sheila V, Campo, M. Saveria

    Published in Journal of general virology (01-02-2010)
    “…1 Division of Pathological Sciences, Institute of Comparative Medicine, University of Glasgow, Glasgow G61 1QH, Scotland, UK 2 Section of Dermatology, Faculty…”
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    Association of High Risk Human Papillomavirus and Breast cancer: A UK based Study by Salman, Nadia Aziz, Davies, Giles, Majidy, Farida, Shakir, Fatima, Akinrinade, Hilda, Perumal, Dhayaneethie, Ashrafi, G. Hossein

    Published in Scientific reports (27-02-2017)
    “…Infection by human papillomaviruses (HPVs) has been implicated in the aetiology of a variety of cancers. Studies evaluating the presence of HPVs in breast…”
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    Down-regulation of MHC class I by bovine papillomavirus E5 oncoproteins by HOSSEIN ASHRAFI, G, TSIRIMONAKI, Emmanouella, MARCHETTI, Barbara, O'BRIEN, Philippa M, SIBBET, Gary J, ANDREW, Linda, CAMPO, M. Saveria

    Published in Oncogene (10-01-2002)
    “…The papillomavirus E5 protein is localized in the endoplasmic reticulum (ER) and Golgi apparatus (GA) of the host cell. Transformed bovine fibroblasts…”
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    The bovine papillomavirus oncoprotein E5 retains MHC class I molecules in the Golgi apparatus and prevents their transport to the cell surface by MARCHETTI, Barbara, ASHRAFI, G. Hossein, TSIRIMONAKI, Emmanouella, O'BRIEN, Philippa M, CAMPO, M. Saveria

    Published in Oncogene (07-11-2002)
    “…During papillomavirus infection, the E5 protein localizes in the cell Golgi apparatus and other endomembrane compartments. Cells transformed by E5 do not…”
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    Prevalence and type distribution of high-risk human papillomavirus in patients with cervical cancer: a population-based study by Haghshenas, Mohammadreza, Golini-Moghaddam, Tahereh, Rafiei, Alireza, Emadeian, Omid, Shykhpour, Ahmad, Ashrafi, G Hossein

    Published in Infectious agents and cancer (06-06-2013)
    “…Cervical cancer is the greater cause of cancer death in women in many developing countries. Persistent infection with human papilloma virus (HPV), primarily…”
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