Search Results - "Ashrafi, G Hossein"
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Synergistic effects of various Her inhibitors in combination with IGF-1R, C-MET and Src targeting agents in breast cancer cell lines
Published in Scientific reports (21-06-2017)“…Overexpression of HER2 has been reported in around 25% of human breast cancers. Despite recent advances in HER2 targeted therapy, many patients still…”
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Ficus carica Latex Modulates Immunity-Linked Gene Expression in Human Papillomavirus Positive Cervical Cancer Cell Lines: Evidence from RNA Seq Transcriptome Analysis
Published in International journal of molecular sciences (01-09-2023)“…Cervical carcinogenesis is the leading cause of cancer-related deaths in women, and the role of high-risk human papillomavirus (HR-HPV) as a possible risk…”
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3
Biological activities of Ficus carica latex for potential therapeutics in Human Papillomavirus (HPV) related cervical cancers
Published in Scientific reports (31-01-2019)“…Infection caused by high-risk human papillomaviruses (HPVs) are implicated in the aetiology of cervical cancer. Although current methods of treatment for…”
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4
Regulatory Effect of Ficus carica Latex on Cell Cycle Progression in Human Papillomavirus-Positive Cervical Cancer Cell Lines: Insights from Gene Expression Analysis
Published in Pharmaceuticals (Basel, Switzerland) (12-12-2023)“…Cervical cancer presents a significant global health concern with high-risk human papillomaviruses (HPVs) identified as the main cause of this cancer. Although…”
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Detection of high-risk Human Papillomavirus in prostate cancer from a UK based population
Published in Scientific reports (10-05-2023)“…Human papillomavirus (HPV) infection is one of the sexually transmitted diseases which have been implicated in the etiology of multiple cancers. To date,…”
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Signal transduction pathway mutations in gastrointestinal (GI) cancers: a systematic review and meta-analysis
Published in Scientific reports (30-10-2020)“…The present study was conducted to evaluate the prevalence of the signaling pathways mutation rate in the Gastrointestinal (GI) tract cancers in a systematic…”
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Prevalence and Type Distribution of High-Risk Human Papillomavirus (HPV) in Breast Cancer: A Qatar Based Study
Published in Cancers (10-06-2020)“…Human papillomavirus (HPV) has been implicated in the etiology of a variety of human cancers. Studies investigating the presence of high-risk (HR) HPV in…”
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Scoring systems of metabolic syndrome and prediction of cardiovascular events: A population based cohort study
Published in Clinical cardiology (Mahwah, N.J.) (01-06-2022)“…Background and Aims Continuous scoring systems were developed versus traditional dichotomous approaches to define metabolic syndrome. The current study was…”
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Concurrent high risk HPV35, HPV45, and HPV59 infections in prostate and bladder cancer tissues of a single patient: A case report
Published in Heliyon (15-08-2024)“…Human papillomavirus (HPV) infections, primarily transmitted through sexual contact, have been linked to various cancers, including cervical, penile, anal,…”
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All 4 di‐leucine motifs in the first hydrophobic domain of the E5 oncoprotein of human papillomavirus type 16 are essential for surface MHC class I downregulation activity and E5 endomembrane localization
Published in International journal of cancer (01-04-2010)“…The E5 oncoprotein of human papillomavirus type 16 downregulates surface MHC Class I and interacts with the heavy chain of the MHC complex via the first…”
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E5 protein of human papillomavirus 16 downregulates HLA class I and interacts with the heavy chain via its first hydrophobic domain
Published in International journal of cancer (01-11-2006)“…Human papillomavirus type 16 E5 protein (HPV‐16 E5) is expressed early in papillomavirus infection and is localised primarily in the cell Golgi apparatus (GA)…”
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A population-based prospective study on obesity-related non-communicable diseases in northern Iran: rationale, study design, and baseline analysis
Published in Frontiers in endocrinology (Lausanne) (2024)“…Iran is facing an epidemiological transition with the increasing burden of non-communicable diseases, such as obesity-related disorders and cardiovascular…”
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E5 protein of human papillomavirus type 16 selectively downregulates surface HLA class I
Published in International journal of cancer (10-01-2005)“…Papillomaviruses have evolved mechanisms that result in escape from host immune surveillance. The E5 protein is expressed early in papillomavirus infection in…”
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Effects of human papillomavirus type 16 E5 deletion mutants on epithelial morphology: functional characterization of each transmembrane domain
Published in Journal of general virology (01-02-2010)“…1 Division of Pathological Sciences, Institute of Comparative Medicine, University of Glasgow, Glasgow G61 1QH, Scotland, UK 2 Section of Dermatology, Faculty…”
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Association of High Risk Human Papillomavirus and Breast cancer: A UK based Study
Published in Scientific reports (27-02-2017)“…Infection by human papillomaviruses (HPVs) has been implicated in the aetiology of a variety of cancers. Studies evaluating the presence of HPVs in breast…”
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Down-regulation of MHC class I by bovine papillomavirus E5 oncoproteins
Published in Oncogene (10-01-2002)“…The papillomavirus E5 protein is localized in the endoplasmic reticulum (ER) and Golgi apparatus (GA) of the host cell. Transformed bovine fibroblasts…”
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The bovine papillomavirus oncoprotein E5 retains MHC class I molecules in the Golgi apparatus and prevents their transport to the cell surface
Published in Oncogene (07-11-2002)“…During papillomavirus infection, the E5 protein localizes in the cell Golgi apparatus and other endomembrane compartments. Cells transformed by E5 do not…”
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A systematic review and meta-analysis of Seroprevalence of Varicella Zoster virus: A nationwide population-based study
Published in Journal of clinical virology (01-02-2017)“…Abstract Varicella zoster virus (VZV) causes chicken pox as a primary infection following which it becomes latent in neurons. It may then reactivate to cause…”
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The Ability of the Framingham Steatosis Index (FSI) to Predict Non-alcoholic Fatty Liver Disease (NAFLD): A Cohort Study
Published in Clinics and research in hepatology and gastroenterology (01-11-2021)“…•FSI is a benefitial tool with strong ability to diagnisis of NAFLD.•New cases of NAFLD could be determined by using FSI tool which showed acceptable ability…”
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Prevalence and type distribution of high-risk human papillomavirus in patients with cervical cancer: a population-based study
Published in Infectious agents and cancer (06-06-2013)“…Cervical cancer is the greater cause of cancer death in women in many developing countries. Persistent infection with human papilloma virus (HPV), primarily…”
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