Search Results - "Ashok, Ajay"
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1
A Low-Profile Ultra-Wideband Absorber Using Lumped Resistor-Loaded Cross Dipoles With Resonant Nodes
Published in IEEE transactions on electromagnetic compatibility (01-10-2022)“…This article presents the design and analysis of a dual-polarized low-profile circuit analog absorber with wideband absorption characteristics. A lossy…”
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2
Retinal Degeneration and Alzheimer's Disease: An Evolving Link
Published in International journal of molecular sciences (02-10-2020)“…Age-related macular degeneration (AMD) and glaucoma are degenerative conditions of the retina and a significant cause of irreversible blindness in developed…”
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3
Epigenetic Regulation of Optic Nerve Development, Protection, and Repair
Published in International journal of molecular sciences (10-08-2022)“…Epigenetic factors are known to influence tissue development, functionality, and their response to pathophysiology. This review will focus on different types…”
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Optimal transcorneal electrical stimulation parameters for preserving photoreceptors in a mouse model of retinitis pigmentosa
Published in Neural regeneration research (01-11-2024)“…JOURNAL/nrgr/04.03/01300535-202419110-00034/figure1/v/2024-03-08T184507Z/r/image-tiff Retinitis pigmentosa is a hereditary retinal disease that affects rod and…”
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5
Neoadjuvant Trastuzumab and Pertuzumab for Early HER2-Positive Breast Cancer: A Real World Experience
Published in The breast journal (30-06-2022)“…Background. Randomized studies of neoadjuvant (NA) trastuzumab and pertuzumab combined with chemotherapy for HER2-positive breast cancers (BC) have reported…”
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6
Transcorneal but not transpalpebral electrical stimulation disrupts mucin homeostasis of the ocular surface
Published in BMC ophthalmology (15-12-2022)“…Transcorneal electrical stimulation (TcES) is increasingly applied as a therapy for preserving and improving vision in retinal neurodegenerative and ischemic…”
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7
Direct modulation of microglial function by electrical field
Published in Frontiers in cell and developmental biology (08-09-2022)“…Non-invasive electric stimulation (ES) employing a low-intensity electric current presents a potential therapeutic modality that can be applied for treating…”
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Release of Iron-Loaded Ferritin in Sodium Iodate-Induced Model of Age Related Macular Degeneration: An In-Vitro and In-Vivo Study
Published in Antioxidants (05-08-2021)“…In this report, we evaluated the role of iron in sodium iodate (NaIO3)-induced model of age-related macular degeneration (AMD) in ARPE-19 cells in-vitro, and…”
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Prion protein modulates glucose homeostasis by altering intracellular iron
Published in Scientific reports (26-04-2018)“…The prion protein (PrP C ), a mainly neuronal protein, is known to modulate glucose homeostasis in mouse models. We explored the underlying mechanism in mouse…”
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10
SoK: Modeling Explainability in Security Analytics for Interpretability, Trustworthiness, and Usability
Published 13-06-2023“…Interpretability, trustworthiness, and usability are key considerations in high-stake security applications, especially when utilizing deep learning models…”
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Prions and prion diseases: Insights from the eye
Published in Experimental eye research (01-10-2020)“…Prion diseases are invariably fatal neurodegenerative disorders that have gained much publicity due to their transmissible nature. Sporadic Creutzfeldt-Jakob…”
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12
Local synthesis of hepcidin in the anterior segment of the eye: A novel observation with physiological and pathological implications
Published in Experimental eye research (01-01-2020)“…The avascular cornea, trabecular meshwork (TM), and lens obtain iron, an essential biometal, from the aqueous humor (AH). The mechanism by which this exchange…”
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Prion protein modulates iron transport in the anterior segment: Implications for ocular iron homeostasis and prion transmission
Published in Experimental eye research (01-10-2018)“…Iron is an essential biometal in the aqueous humor, the principal source of nutrients for the avascular cornea and the lens. Here, we explored whether the…”
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14
Bioengineering strategy to promote CNS nerve growth and regeneration via chronic glutamate signaling
Published in Acta biomaterialia (18-10-2024)“…Being part of the mature mammalian central nervous system, impairments of the retina and optic nerves caused by trauma or diseases often cannot be restored…”
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15
Electrical stimulation alters DNA methylation and promotes neurite outgrowth
Published in Journal of cellular biochemistry (01-10-2023)“…Abstract Electrical stimulation (ES) influences neural regeneration and functionality. We here investigate whether ES regulates DNA demethylation, a critical…”
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TGFβ2-Hepcidin Feed-Forward Loop in the Trabecular Meshwork Implicates Iron in Glaucomatous Pathology
Published in Investigative ophthalmology & visual science (17-03-2020)“…Elevated levels of transforming-growth-factor (TGF)-β2 in the trabecular meshwork (TM) and aqueous humor are associated with primary open-angle glaucoma…”
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β-Cleavage of the prion protein in the human eye: Implications for the spread of infectious prions and human ocular disorders
Published in Experimental eye research (01-11-2021)“…Recently, we reported β-cleavage of the prion protein (PrPC) in human ocular tissues. Here, we explored whether this is unique to the human eye, and its…”
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Corrigendum to “SurR9C84A protects and recovers human cardiomyocytes from hypoxia induced apoptosis” [Exp. Cell Res. 350(1) (2017) 19–31]
Published in Experimental cell research (01-10-2018)Get full text
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α-Synuclein modulates fibronectin expression in the trabecular meshwork independent of TGFβ2
Published in Experimental eye research (01-01-2023)“…α-Synuclein (α-Syn) is implicated in Parkinson's disease (PD), a neuromotor disorder with prominent visual symptoms. The underlying cause of motor dysfunction…”
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Prion protein facilitates retinal iron uptake and is cleaved at the β-site: Implications for retinal iron homeostasis in prion disorders
Published in Scientific reports (29-08-2017)“…Prion disease-associated retinal degeneration is attributed to PrP-scrapie (PrP Sc ), a misfolded isoform of prion protein (PrP C ) that accumulates in the…”
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