Search Results - "Ashley Moseman, E."

Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection by Yao, Chen, Sun, Hong-Wei, Lacey, Neal E., Ji, Yun, Moseman, E. Ashley, Shih, Han-Yu, Heuston, Elisabeth F., Kirby, Martha, Anderson, Stacie, Cheng, Jun, Khan, Omar, Handon, Robin, Reilley, Julie, Fioravanti, Jessica, Hu, Jinhui, Gossa, Selamawit, Wherry, E. John, Gattinoni, Luca, McGavern, Dorian B., O’Shea, John J., Schwartzberg, Pamela L., Wu, Tuoqi

“…Progenitor-like CD8 + T cells mediate long-term immunity to chronic infection and cancer and respond potently to immune checkpoint blockade. These cells share…”
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Battling brain-eating amoeba: Enigmas surrounding immunity to Naegleria fowleri by Moseman, E Ashley

“…Yet, because distinguishing PAM from other types of meningitis and encephalitis can be difficult, it’s likely that many cases of PAM are simply never…”
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The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction by Collins, Nicholas, Han, Seong-Ji, Enamorado, Michel, Link, Verena M., Huang, Bonnie, Moseman, E. Ashley, Kishton, Rigel J., Shannon, John P., Dixit, Dhaval, Schwab, Susan R., Hickman, Heather D., Restifo, Nicholas P., McGavern, Dorian B., Schwartzberg, Pamela L., Belkaid, Yasmine

“…Mammals evolved in the face of fluctuating food availability. How the immune system adapts to transient nutritional stress remains poorly understood. Here, we…”
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BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells by Yao, Chen, Lou, Guohua, Sun, Hong-Wei, Zhu, Ziang, Sun, Yi, Chen, Zeyu, Chauss, Daniel, Moseman, E. Ashley, Cheng, Jun, D’Antonio, Marc A., Shi, Wangke, Shi, Junwei, Kometani, Kohei, Kurosaki, Tomohiro, Wherry, E. John, Afzali, Behdad, Gattinoni, Luca, Zhu, Yuwen, McGavern, Dorian B., O’Shea, John J., Schwartzberg, Pamela L., Wu, Tuoqi

“…During chronic infection and cancer, a self-renewing CD8 + T cell subset maintains long-term immunity and is critical to the effectiveness of immunotherapy…”
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Chemokine Guidance of Central Memory T Cells Is Critical for Antiviral Recall Responses in Lymph Nodes by Sung, Jung Hwan, Zhang, Han, Moseman, E. Ashley, Alvarez, David, Iannacone, Matteo, Henrickson, Sarah E., de la Torre, Juan C., Groom, Joanna R., Luster, Andrew D., von Andrian, Ulrich H.

“…A defining feature of vertebrate immunity is the acquisition of immunological memory, which confers enhanced protection against pathogens by mechanisms that…”
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Critical role for the chemokine receptor CXCR6 in NK cell–mediated antigen-specific memory of haptens and viruses by Paust, Silke, Gill, Harvinder S, Wang, Bao-Zhong, Flynn, Michael P, Moseman, E Ashley, Senman, Balimkiz, Szczepanik, Marian, Telenti, Amalio, Askenase, Philip W, Compans, Richard W, von Andrian, Ulrich H

“…NK cells confer innate immune functions. Von Andrian and colleagues show that hepatic NK cells bearing CXCR6 receptors confer antigen-specific NK cell memory…”
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TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection by Wu, Tuoqi, Shin, Hyun Mu, Moseman, E. Ashley, Ji, Yun, Huang, Bonnie, Harly, Christelle, Sen, Jyoti M., Berg, Leslie J., Gattinoni, Luca, McGavern, Dorian B., Schwartzberg, Pamela L.

“…T follicular helper (TFH) and T helper 1 (Th1) cells generated after viral infections are critical for the control of infection and the development of…”
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Reversal of the T cell immune system reveals the molecular basis for T cell lineage fate determination in the thymus by Shinzawa, Miho, Moseman, E. Ashley, Gossa, Selamawit, Mano, Yasuko, Bhattacharya, Abhisek, Guinter, Terry, Alag, Amala, Chen, Xiongfong, Cam, Maggie, McGavern, Dorian B., Erman, Batu, Singer, Alfred

“…T cell specificity and function are linked during development, as MHC-II-specific TCR signals generate CD4 helper T cells and MHC-I-specific TCR signals…”
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Aging-related olfactory loss is associated with olfactory stem cell transcriptional alterations in humans by Oliva, Allison D, Gupta, Rupali, Issa, Khalil, Abi Hachem, Ralph, Jang, David W, Wellford, Sebastian A, Moseman, E Ashley, Matsunami, Hiroaki, Goldstein, Bradley J

“…BACKGROUNDPresbyosmia, or aging-related olfactory loss, occurs in a majority of humans over age 65 years, yet remains poorly understood, with no specific…”
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B Cell Maintenance of Subcapsular Sinus Macrophages Protects against a Fatal Viral Infection Independent of Adaptive Immunity by Moseman, E. Ashley, Iannacone, Matteo, Bosurgi, Lidia, Tonti, Elena, Chevrier, Nicolas, Tumanov, Alexei, Fu, Yang-Xin, Hacohen, Nir, von Andrian, Ulrich H.

“…Neutralizing antibodies have been thought to be required for protection against acutely cytopathic viruses, such as the neurotropic vesicular stomatitis virus…”
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Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus by Guidotti, Luca G, Henrickson, Sarah E, Bosurgi, Lidia, Tonti, Elena, Whelan, Sean P, von Andrian, Ulrich H, Moseman, E. Ashley, Iannacone, Matteo, Junt, Tobias

“…Lymph nodes (LNs) capture microorganisms that breach the body's external barriers and enter draining lymphatics, limiting the systemic spread of pathogens…”
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Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells by Massberg, Steffen, Lang, Philipp A, Mempel, Thorsten R, van Rooijen, Nico, Whelan, Sean P, Moseman, E. Ashley, Henrickson, Sarah E, Boes, Marianne, Di Paolo, Nelson C, Shayakhmetov, Dmitry M, Fink, Katja, von Andrian, Ulrich H, Junt, Tobias, Iannacone, Matteo

“…Lymph nodes prevent the systemic dissemination of pathogens such as viruses that infect peripheral tissues after penetrating the body's surface barriers. They…”
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Necroptosis stimulates interferon-mediated protective anti-tumor immunity by Rucker, A. Justin, Park, Christa S., Li, Qi Jing, Moseman, E. Ashley, Chan, Francis Ka-Ming

“…Necroptosis is an inflammatory form of cell suicide that critically depends on the kinase activity of Receptor Interacting Protein Kinase 3 (RIPK3). Previous…”
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Immunosurveillance by Hematopoietic Progenitor Cells Trafficking through Blood, Lymph, and Peripheral Tissues by Massberg, Steffen, Schaerli, Patrick, Knezevic-Maramica, Irina, Köllnberger, Maria, Tubo, Noah, Moseman, E. Ashley, Huff, Ines V., Junt, Tobias, Wagers, Amy J., Mazo, Irina B., von Andrian, Ulrich H.

“…Constitutive egress of bone marrow (BM)-resident hematopoietic stem and progenitor cells (HSPCs) into the blood is a well-established phenomenon, but the…”
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Distinct olfactory mucosal macrophage populations mediate neuronal maintenance and pathogen defense by Wellford, Sebastian A., Chen, Ching-Wen, Vukovic, Marko, Batich, Kristen A., Lin, Elliot, Shalek, Alex K., Ordovas-Montanes, Jose, Moseman, Annie Park, Moseman, E. Ashley

“…The olfactory mucosa is important for both the sense of smell and as a mucosal immune barrier to the upper airway and brain. However, little is known about how…”
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Natural Antibody and Complement Mediate Neutralization of Influenza Virus in the Absence of Prior Immunity by JAYASEKERA, Jerome P, MOSEMAN, E. Ashley, CARROLL, Michael C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Enolase inhibitors as therapeutic leads for Naegleria fowleri infection by Milanes, Jillian E, Yan, Victoria C, Pham, Cong-Dat, Muller, Florian, Kwain, Samuel, Rees, Kerrick C, Dominy, Brian N, Whitehead, Daniel C, Millward, Steven W, Bolejack, Madison, Shek, Roger, Tillery, Logan, Phan, Isabelle Q, Staker, Bart, Moseman, E Ashley, Zhang, Xiang, Ma, Xipeng, Jebet, Audriy, Yin, Xinmin, Morris, James C

“…Infections with the pathogenic free-living amoebae Naegleria fowleri can lead to life-threatening illnesses including catastrophic primary amoebic…”
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Emerging nanotechnology approaches for HIV/AIDS treatment and prevention by Mamo, Tewodros, Moseman, E Ashley, Kolishetti, Nagesh, Salvador-Morales, Carolina, Shi, Jinjun, Kuritzkes, Daniel R, Langer, Robert, von Andrian, Ulrich, Farokhzad, Omid C

“…Currently, there is no cure and no preventive vaccine for HIV/AIDS. Combination antiretroviral therapy has dramatically improved treatment, but it has to be…”
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Early detection of cerebrovascular pathology and protective antiviral immunity by MRI by Liu, Li, Dodd, Steve, Hunt, Ryan D, Pothayee, Nikorn, Atanasijevic, Tatjana, Bouraoud, Nadia, Maric, Dragan, Moseman, E Ashley, Gossa, Selamawit, McGavern, Dorian B, Koretsky, Alan P

“…Central nervous system (CNS) infections are a major cause of human morbidity and mortality worldwide. Even patients that survive, CNS infections can have…”
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Heterogeneity of Antiviral Responses in the Upper Respiratory Tract Mediates Differential Non-lytic Clearance of Influenza Viruses by Dumm, Rebekah E., Wellford, Sebastian A., Moseman, E. Ashley, Heaton, Nicholas S.

“…Influenza viruses initiate infection in the upper respiratory tract (URT), but early viral tropism and the importance of cell-type-specific antiviral responses…”
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