Search Results - "Ashley, Rachel"

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    Activities of gyrase and topoisomerase IV on positively supercoiled DNA by Ashley, Rachel E, Dittmore, Andrew, McPherson, Sylvia A, Turnbough, Jr, Charles L, Neuman, Keir C, Osheroff, Neil

    Published in Nucleic acids research (19-09-2017)
    “…Although bacterial gyrase and topoisomerase IV have critical interactions with positively supercoiled DNA, little is known about the actions of these enzymes…”
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    Journal Article
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    Natural Products as Topoisomerase II Poisons: Effects of Thymoquinone on DNA Cleavage Mediated by Human Topoisomerase IIα by Ashley, Rachel E, Osheroff, Neil

    Published in Chemical research in toxicology (19-05-2014)
    “…The seeds of Nigella sativa (often referred to as black seed) have long been utilized as a medicinal herb in Middle Eastern, Northern African, and Indian…”
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    Journal Article
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    Evidence for a role of viruses in the thermal sensitivity of coral photosymbionts by Levin, Rachel Ashley, Voolstra, Christian Robert, Weynberg, Karen Dawn, van Oppen, Madeleine Josephine Henriette

    Published in The ISME Journal (01-03-2017)
    “…Symbiodinium , the dinoflagellate photosymbiont of corals, is posited to become more susceptible to viral infections when heat-stressed. To investigate this…”
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    Journal Article
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    Oxidative Transformation of Demethoxy- and Bisdemethoxycurcumin: Products, Mechanism of Formation, and Poisoning of Human Topoisomerase IIα by Gordon, Odaine N, Luis, Paula B, Ashley, Rachel E, Osheroff, Neil, Schneider, Claus

    Published in Chemical research in toxicology (18-05-2015)
    “…Extracts from the rhizome of the turmeric plant are widely consumed as anti-inflammatory dietary supplements. Turmeric extract contains the three curcuminoids,…”
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    Journal Article
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    Recognition of DNA Supercoil Geometry by Mycobacterium tuberculosis Gyrase by Ashley, Rachel E, Blower, Tim R, Berger, James M, Osheroff, Neil

    Published in Biochemistry (Easton) (10-10-2017)
    “…Mycobacterium tuberculosis encodes only a single type II topoisomerase, gyrase. As a result, this enzyme likely carries out the cellular functions normally…”
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    Journal Article
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    Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance by Ashley, Rachel E, Lindsey, R. Hunter, McPherson, Sylvia A, Turnbough, Charles L, Kerns, Robert J, Osheroff, Neil

    Published in Biochemistry (Easton) (15-08-2017)
    “…Gyrase appears to be the primary cellular target for quinolone antibacterials in multiple pathogenic bacteria, including Bacillus anthracis, the causative…”
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    Journal Article
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    Catalytic Core of Human Topoisomerase IIα: Insights into Enzyme–DNA Interactions and Drug Mechanism by Lindsey, R. Hunter, Pendleton, MaryJean, Ashley, Rachel E, Mercer, Susan L, Deweese, Joseph E, Osheroff, Neil

    Published in Biochemistry (Easton) (21-10-2014)
    “…Coordination between the N-terminal gate and the catalytic core of topoisomerase II allows the proper capture, cleavage, and transport of DNA during the…”
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    Journal Article
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    Synthesis and evaluation of ether-linked demethylepipodophyllotoxin dimers by Dunlap, Norma, Salyard, Tracy L J, Pathiranage, Anuradha Liyana, Stubblefield, Jeannie, Pitts, Steven L, Ashley, Rachel E, Osheroff, Neil

    Published in Bioorganic & medicinal chemistry letters (15-12-2014)
    “…A series of novel ether-linked dimers of demethylepipodophyllotoxin are topoisomerase II poisons that exhibit higher levels of double-stranded versus…”
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    Journal Article
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    Miss Monstress: The Trial of Womanhood and Rhetorical Framing of Texas Women on Trial for Murder by McShane, Rachel Ashley

    Published 01-01-2024
    “…This dissertation is a rhetorical analysis of the cases of three Texas women who were charged with murder. I examine the rhetoric used by the media and the…”
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    Dissertation
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    Feasibility of a Critical Experiment Utilizing Uranium Dioxide-Beryllium Oxide with Neutron Spectrum Shifting Capabilities by Raster, Ashley Rachel

    Published 01-01-2022
    “…The goal of this project is to determine the feasibility of utilizing Annular Core Research Reactor (ACRR) fuel in core design with Sandia Pulse Reactor…”
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    Dissertation
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    Planning for Seattle's Mandatory Retrofitting Policy: A Retrofitting Plan for the Northern Pacific Hotel by Vickers, Rachel Ashley

    Published 01-01-2019
    “…A retrofitting resource for the NP Hotel focusing on retrofitting methods and funding options…”
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    Dissertation
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    Microfluidic chambers used to test whether episodic breathing is regulated by the pons in turtle brainstems by Bartman, Michelle Ellen, Krisp, Ashley Rachel, Johnson, Stephen Mark

    Published in The FASEB journal (01-04-2010)
    “…Our goal is to locate and characterize neurons controlling respiratory motor burst timing. Episodic breathing (clusters of fictive breaths separated by apneas)…”
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    Journal Article
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