Search Results - "Ashley, Noah T"
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Inflammation: Mechanisms, Costs, and Natural Variation
Published in Annual review of ecology, evolution, and systematics (01-01-2012)“…Inflammation is a pervasive phenomenon that operates during severe perturbations of homeostasis, such as infection, injury, and exposure to contaminants, and…”
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Temporal dynamics of pro-inflammatory cytokines and serum corticosterone following acute sleep fragmentation in male mice
Published in PloS one (14-12-2023)“…Obstructive sleep apnea is increasing worldwide, leading to disordered sleep patterns and inflammatory responses in brain and peripheral tissues that…”
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Transcriptomic analysis of immune response to bacterial lipopolysaccharide in zebra finch (Taeniopygia guttata)
Published in BMC genomics (14-08-2019)“…Despite the convergence of rapid technological advances in genomics and the maturing field of ecoimmunology, our understanding of the genes that regulate…”
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Effect of glucocorticoid blockade on inflammatory responses to acute sleep fragmentation in male mice
Published in PeerJ (San Francisco, CA) (28-06-2024)“…The association between sleep and the immune-endocrine system is well recognized, but the nature of that relationship is not well understood. Sleep…”
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Contrasting effects of sleep fragmentation and angiotensin-II treatment upon pro-inflammatory responses of mice
Published in Scientific reports (30-08-2022)“…Disordered sleep promotes inflammation in brain and peripheral tissues, but the mechanisms that regulate these responses are poorly understood. One hypothesis…”
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Androgens and the Immunocompetence Handicap Hypothesis: Unraveling Direct and Indirect Pathways of Immunosuppression in Song Sparrows
Published in The American naturalist (01-10-2004)“…The immunocompetence handicap hypothesis proposes that testosterone (T)‐dependent sexual signals are honest indicators of male health or genetic quality…”
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Alpha- and beta- adrenergic receptors regulate inflammatory responses to acute and chronic sleep fragmentation in mice
Published in PeerJ (San Francisco, CA) (24-06-2021)“…Sleep is a recuperative process, and its dysregulation has cognitive, metabolic, and immunological effects that are largely deleterious to human health…”
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Acute sleep fragmentation does not alter pro-inflammatory cytokine gene expression in brain or peripheral tissues of leptin-deficient mice
Published in PeerJ (San Francisco, CA) (19-02-2018)“…Obesity and sleep fragmentation (SF) are often co-occurring pro-inflammatory conditions in patients with obstructive sleep apnea. Leptin is a peptide hormone…”
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Neuroendocrine-immune circuits, phenotypes, and interactions
Published in Hormones and behavior (01-01-2017)“…Multidirectional interactions among the immune, endocrine, and nervous systems have been demonstrated in humans and non-human animal models for many decades by…”
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Hormonal, behavioral, and thermoregulatory responses to bacterial lipopolysaccharide in captive and free-living white-crowned sparrows ( Zonotrichia leucophrys gambelii)
Published in Hormones and behavior (2006)“…Exposing vertebrates to pathogenic organisms or inflammatory stimuli, such as bacterial lipopolysaccharide (LPS), activates the immune system and triggers the…”
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Acute sleep fragmentation induces tissue-specific changes in cytokine gene expression and increases serum corticosterone concentration
Published in American journal of physiology. Regulatory, integrative and comparative physiology (15-06-2015)“…Sleep deprivation induces acute inflammation and increased glucocorticosteroids in vertebrates, but effects from fragmented, or intermittent, sleep are poorly…”
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Peripheral Sympathectomy Alters Neuroinflammatory and Microglial Responses to Sleep Fragmentation in Female Mice
Published in Neuroscience (21-11-2022)“…•Acute and chronic SF promoted neuroinflammation and microglia activity in female mice.•Chronic SF induced hyper-ramification in resting microglia.•One week of…”
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Effect of sleep loss on executive function and plasma corticosterone levels in an arctic-breeding songbird, the Lapland longspur (Calcarius lapponicus)
Published in Hormones and behavior (01-06-2020)“…Sleep is a fundamental component of vertebrate life, although its exact functions remain unclear. Animals deprived of sleep typically show reduced…”
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Modulation of the hypothalamic–pituitary–adrenal axis of an Arctic–breeding polygynandrous songbird, the Smith's longspur, Calcarius pictus
Published in Proceedings of the Royal Society. B, Biological sciences (07-09-2003)“…To successfully reproduce in the Arctic, birds must modulate their neuroendocrine and behavioural systems. These adjustments include an attenuation of the…”
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Light at night disrupts diel patterns of cytokine gene expression and endocrine profiles in zebra finch (Taeniopygia guttata)
Published in Scientific reports (01-11-2019)“…Increased exposure to light pollution perturbs physiological processes through misalignment of daily rhythms at the cellular and tissue levels. Effects of…”
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Androgens, interspecific competition and species replacement in hybridizing warblers
Published in Proceedings of the Royal Society. B, Biological sciences (07-12-2004)“…) have replaced hermit warblers (…”
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Short-Term Sleep Loss Alters Cytokine Gene Expression in Brain and Peripheral Tissues and Increases Plasma Corticosterone of Zebra Finch (Taeniopygia guttata)
Published in Physiological and biochemical zoology (01-01-2019)“…Lack of sleep incurs physiological costs that include increased inflammation and alterations in the hypothalamic-pituitary-adrenal axis. Specifically, sleep…”
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Chemical sympathectomy reduces peripheral inflammatory responses to acute and chronic sleep fragmentation
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-04-2020)“…Sleep loss contributes to the development of cardiovascular, metabolic, and neurological disorders by promoting a systemic proinflammatory phenotype. The…”
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Novel environment influences the effect of paradoxical sleep deprivation upon brain and peripheral cytokine gene expression
Published in Neuroscience letters (26-02-2016)“…•Paradoxical sleep deprivation elevated proinflammatory responses in brain/periphery.•Paradoxical sleep deprivation increased baseline serum…”
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