Search Results - "Ashish K. Khanna"

Perioperative myocardial injury and the contribution of hypotension by Sessler, Daniel I., Khanna, Ashish K.

“…Mortality in the month following surgery is about 1000 times greater than anesthesia-related intraoperative mortality, and myocardial injury appears to be the…”
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Automated continuous noninvasive ward monitoring: future directions and challenges by Khanna, Ashish K, Hoppe, Phillip, Saugel, Bernd

“…Automated continuous noninvasive ward monitoring may enable subtle changes in vital signs to be recognized. There is already some evidence that automated ward…”
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An updated "norepinephrine equivalent" score in intensive care as a marker of shock severity by Kotani, Yuki, Di Gioia, Annamaria, Landoni, Giovanni, Belletti, Alessandro, Khanna, Ashish K

“…Vasopressors and fluids are the cornerstones for the treatment of shock. The current international guidelines on shock recommend norepinephrine as the…”
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Myocardial Injury After Noncardiac Surgery: Preoperative, Intraoperative, and Postoperative Aspects, Implications, and Directions by Ruetzler, Kurt, Khanna, Ashish K., Sessler, Daniel I.

“…Myocardial injury after noncardiac surgery (MINS) differs from myocardial infarction in being defined by troponin elevation apparently from cardiac ischemia…”
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Prevalence and Outcomes of Infection Among Patients in Intensive Care Units in 2017 by Vincent, Jean-Louis, Sakr, Yasser, Singer, Mervyn, Martin-Loeches, Ignacio, Machado, Flavia R, Marshall, John C, Finfer, Simon, Pelosi, Paolo, Brazzi, Luca, Aditianingsih, Dita, Timsit, Jean-François, Du, Bin, Wittebole, Xavier, Máca, Jan, Kannan, Santhana, Gorordo-Delsol, Luis A, De Waele, Jan J, Mehta, Yatin, Bonten, Marc J. M, Khanna, Ashish K, Kollef, Marin, Human, Mariesa, Angus, Derek C

“…IMPORTANCE: Infection is frequent among patients in the intensive care unit (ICU). Contemporary information about the types of infections, causative pathogens,…”
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The relationship between ICU hypotension and in-hospital mortality and morbidity in septic patients by Maheshwari, Kamal, Nathanson, Brian H., Munson, Sibyl H., Khangulov, Victor, Stevens, Mitali, Badani, Hussain, Khanna, Ashish K., Sessler, Daniel I.

“…Purpose Current guidelines recommend maintaining a mean arterial pressure (MAP) ≥ 65 mmHg in septic patients. However, the relationship between hypotension and…”
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COVID-19 and the RAAS-a potential role for angiotensin II? by Busse, Laurence W, Chow, Jonathan H, McCurdy, Michael T, Khanna, Ashish K

“…Keywords: Coronavirus, COVID-19, Angiotensin II, ACE2, RAAS…”
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Association Between Mean Arterial Pressure and Acute Kidney Injury and a Composite of Myocardial Injury and Mortality in Postoperative Critically Ill Patients: A Retrospective Cohort Analysis by Khanna, Ashish K., Maheshwari, Kamal, Mao, Guangmei, Liu, Liu, Perez-Protto, Silvia E., Chodavarapu, Praneeta, Schacham, Yehoshua N., Sessler, Daniel I.

“…OBJECTIVES:Hypotension thresholds that provoke renal injury, myocardial injury, and mortality in critical care patients remain unknown. We primarily sought to…”
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Response to: norepinephrine formulation for equivalent vasopressive score by Kotani, Yuki, Landoni, Giovanni, Belletti, Alessandro, Khanna, Ashish K

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Angiotensin I and angiotensin II concentrations and their ratio in catecholamine-resistant vasodilatory shock by Bellomo, Rinaldo, Wunderink, Richard G, Szerlip, Harold, English, Shane W, Busse, Laurence W, Deane, Adam M, Khanna, Ashish K, McCurdy, Michael T, Ostermann, Marlies, Young, Paul J, Handisides, Damian R, Chawla, Lakhmir S, Tidmarsh, George F, Albertson, Timothy E

“…In patients with vasodilatory shock, plasma concentrations of angiotensin I (ANG I) and II (ANG II) and their ratio may reflect differences in the response to…”
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Association Between Mobilization and Composite Postoperative Complications Following Major Elective Surgery by Turan, Alparslan, Khanna, Ashish K, Brooker, Jack, Saha, Amit K, Clark, Clancy J, Samant, Anusha, Ozcimen, Elif, Pu, Xuan, Ruetzler, Kurt, Sessler, Daniel I

“…Mobilization after surgery is a key component of Enhanced Recovery after Surgery (ERAS) pathways. To evaluate the association between mobilization and a…”
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Postoperative hypotension in patients discharged to the intensive care unit after non-cardiac surgery is associated with adverse clinical outcomes by Smischney, Nathan J, Shaw, Andrew D, Stapelfeldt, Wolf H, Boero, Isabel J, Chen, Qinyu, Stevens, Mitali, Khanna, Ashish K

“…The postoperative period is critical for a patient's recovery, and postoperative hypotension, specifically, is associated with adverse clinical outcomes and…”
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Defending a mean arterial pressure in the intensive care unit: Are we there yet? by Khanna, Ashish K.

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Initiating angiotensin II at lower vasopressor doses in vasodilatory shock: an exploratory post-hoc analysis of the ATHOS-3 clinical trial by Wieruszewski, Patrick M, Bellomo, Rinaldo, Busse, Laurence W, Ham, Kealy R, Zarbock, Alexander, Khanna, Ashish K, Deane, Adam M, Ostermann, Marlies, Wunderink, Richard G, Boldt, David W, Kroll, Stew, Greenfeld, Chuck R, Hodges, Tony, Chow, Jonathan H

“…High dose vasopressors portend poor outcome in vasodilatory shock. We aimed to evaluate the impact of baseline vasopressor dose on outcomes in patients treated…”
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Agreement between cardiac output estimation with a wireless, wearable pulse decomposition analysis device and continuous thermodilution in post cardiac surgery intensive care unit patients by Khanna, Ashish K., Garcia, Julio O, Saha, Amit K, Harris, Lynnette, Baruch, Martin, Martin, R. Shayn

“…Purpose Pulse Decomposition Analysis (PDA) uses integration of the systolic area of a distally transmitted aortic pulse as well as arterial stiffness estimates…”
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Enhanced monitoring for postoperative hospital wards - Evidence to implementation by Upadhyay, Prateek, Hicks, Megan Henley, Khanna, Ashish K

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Timing of vasoactive agents and corticosteroid initiation in septic shock by Ammar, Mahmoud A., Ammar, Abdalla A., Wieruszewski, Patrick M., Bissell, Brittany D., T. Long, Micah, Albert, Lauren, Khanna, Ashish K., Sacha, Gretchen L.

“…Septic shock remains a health care concern associated with significant morbidity and mortality. The Surviving Sepsis Campaign Guidelines for Management of…”
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Renin in critically ill patients by Kotani, Yuki, Chappell, Mark, Landoni, Giovanni, Zarbock, Alexander, Bellomo, Rinaldo, Khanna, Ashish K.

“…The renin-angiotensin system (RAS) constitutes one of the principal mechanisms to maintain hemodynamic and fluid homeostasis. However, most research until now…”
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Continuous Monitoring Detected Respiratory Depressive Episodes in Proximity to Adverse Respiratory Events During the PRODIGY Trial by Kor, Jennifer J., Sprung, Juraj, Khanna, Ashish K., Weingarten, Toby N.

“…The PRediction of Opioid-induced respiratory Depression In patients monitored by capnoGraphY (PRODIGY) trial was a multicenter prospective trial conducted to…”
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Association of systolic, diastolic, mean, and pulse pressure with morbidity and mortality in septic ICU patients: a nationwide observational study by Khanna, Ashish K., Kinoshita, Takahiro, Natarajan, Annamalai, Schwager, Emma, Linn, Dustin D., Dong, Junzi, Ghosh, Erina, Vicario, Francesco, Maheshwari, Kamal

“…Background Intensivists target different blood pressure component values to manage intensive care unit (ICU) patients with sepsis. We aimed to evaluate the…”
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