Search Results - "Ashinsky, Beth G."

Cell morphology and mechanosensing can be decoupled in fibrous microenvironments and identified using artificial neural networks by Bonnevie, Edward D., Ashinsky, Beth G., Dekky, Bassil, Volk, Susan W., Smith, Harvey E., Mauck, Robert L.

“…Cells interpret cues from and interact with fibrous microenvironments through the body based on the mechanics and organization of these environments and the…”
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Treatment of Symptomatic Bunionette Deformity with Distal Metatarsal Metaphyseal Osteotomy with no Fixation or Strapping by Al Ramlawi, Akram, Patel, Dev, Ashinsky, Beth G., Vulcano, Ettore

“…Category: Lesser Toes; Bunion Introduction/ Purpose: Bunionette deformity (BD) is a painful condition of the fifth metatarsal characterized by an osseous…”
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Development of a standardized histopathology scoring system for intervertebral disc degeneration and regeneration in rabbit models‐An initiative of the ORSspine section by Gullbrand, Sarah E., Ashinsky, Beth G., Lai, Alon, Gansau, Jennifer, Crowley, James, Cunha, Carla, Engiles, Julie B., Fusellier, Marion, Muehleman, Carol, Pelletier, Matthew, Presciutti, Steven, Schol, Jordy, Takeoka, Yoshiki, Yurube, Takashi, Zhang, Yejia, Masuda, Koichi, Iatridis, James C.

“…Background The rabbit lumbar spine is a commonly utilized model for studying intervertebral disc degeneration and for the pre‐clinical evaluation of…”
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Multiparametric Classification of Skin from Osteogenesis Imperfecta Patients and Controls by Quantitative Magnetic Resonance Microimaging by Ashinsky, Beth G, Fishbein, Kenneth W, Carter, Erin M, Lin, Ping-Chang, Pleshko, Nancy, Raggio, Cathleen L, Spencer, Richard G

“…The purpose of this study is to evaluate the ability of quantitative magnetic resonance imaging (MRI) to discriminate between skin biopsies from individuals…”
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Restoration of physiologic loading modulates engineered intervertebral disc structure and function in an in vivo model by Gullbrand, Sarah E., Kim, Dong Hwa, Ashinsky, Beth G., Bonnevie, Edward D., Smith, Harvey E., Mauck, Robert L.

“…Tissue‐engineered whole disc replacements are an emerging treatment strategy for advanced intervertebral disc degeneration. A challenge facing the translation…”
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Fracturing the Lateral Hinge Improves Radiographic Alignment and Does Not Affect Clinical Outcomes of the Minimally Invasive Akin Osteotomy by Marciano, Gerard, Ashinsky, Beth G., Mysore, Nishad, Vulcano, Ettore

“…Background: Intraoperative fracture of the lateral cortex is common during Akin osteotomy. In a recent study, lateral cortex fracture did not impede healing or…”
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Percutaneous Fifth Metatarsal Osteotomy for Bunionette Deformity Without Fixation or Strapping: A Retrospective Study by Al Ramlawi, Akram, Patel, Dev Paul, Ashinsky, Beth G., Aiyer, Amiethab A., Vulcano, Ettore

“…Background: Bunionette deformity (BD) is a painful condition of the fifth metatarsal characterized by an osseous prominence and fifth toe varus deformity. The…”
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Enabling early detection of osteoarthritis from presymptomatic cartilage texture maps via transport-based learning by Kundu, Shinjini, Ashinsky, Beth G., Bouhrara, Mustapha, Dam, Erik B., Demehri, Shadpour, Shifat-E-Rabbi, Mohammad, Spencer, Richard G., Urish, Kenneth L., Rohde, Gustavo K.

“…Many diseases have no visual cues in the early stages, eluding image-based detection. Today, osteoarthritis (OA) is detected after bone damage has occurred, at…”
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Intervertebral Disc Degeneration Is Associated With Aberrant Endplate Remodeling and Reduced Small Molecule Transport by Ashinsky, Beth G, Bonnevie, Edward D, Mandalapu, Sai A, Pickup, Stephen, Wang, Chao, Han, Lin, Mauck, Robert L, Smith, Harvey E, Gullbrand, Sarah E

“…ABSTRACT The intervertebral disc is the largest avascular structure in the body, and cells within the disc rely on diffusive transport via vasculature located…”
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Long-term mechanical function and integration of an implanted tissue-engineered intervertebral disc by Gullbrand, Sarah E, Ashinsky, Beth G, Bonnevie, Edward D, Kim, Dong Hwa, Engiles, Julie B, Smith, Lachlan J, Elliott, Dawn M, Schaer, Thomas P, Smith, Harvey E, Mauck, Robert L

“…Tissue engineering holds great promise for the treatment of advanced intervertebral disc degeneration. However, assessment of in vivo integration and…”
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Predicting early symptomatic osteoarthritis in the human knee using machine learning classification of magnetic resonance images from the osteoarthritis initiative by Ashinsky, Beth G., Bouhrara, Mustapha, Coletta, Christopher E., Lehallier, Benoit, Urish, Kenneth L., Lin, Ping‐Chang, Goldberg, Ilya G., Spencer, Richard G.

“…ABSTRACT The purpose of this study is to evaluate the ability of a machine learning algorithm to classify in vivo magnetic resonance images (MRI) of human…”
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Sacrificial Fibers Improve Matrix Distribution and Micromechanical Properties in a Tissue-Engineered Intervertebral Disc by Ashinsky, Beth G., Gullbrand, Sarah E., Bonnevie, Edward D., Wang, Chao, Kim, Dong Hwa, Han, Lin, Mauck, Robert L., Smith, Harvey E.

“…Tissue-engineered replacement discs are an area of intense investigation for the treatment of end-stage intervertebral disc (IVD) degeneration. These living…”
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Correlations between quantitative T2 and T1ρ MRI, mechanical properties and biochemical composition in a rabbit lumbar intervertebral disc degeneration model by Gullbrand, Sarah E., Ashinsky, Beth G., Martin, John T., Pickup, Stephen, Smith, Lachlan J., Mauck, Robert L., Smith, Harvey E.

“…ABSTRACT Improved diagnostic measures for intervertebral disc degeneration are necessary to facilitate early detection and treatment. The aim of this study was…”
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Degeneration alters structure‐function relationships at multiple length‐scales and across interfaces in human intervertebral discs by Ashinsky, Beth G., Gullbrand, Sarah E., Wang, Chao, Bonnevie, Edward D., Han, Lin, Mauck, Robert L., Smith, Harvey E.

“…Intervertebral disc (IVD) degeneration and associated back pain place a significant burden on the population. IVD degeneration is a progressive cascade of…”
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Noise Estimation and Reduction in Magnetic Resonance Imaging Using a New Multispectral Nonlocal Maximum-likelihood Filter by Bouhrara, Mustapha, Bonny, Jean-Marie, Ashinsky, Beth G., Maring, Michael C., Spencer, Richard G.

“…Denoising of magnetic resonance (MR) images enhances diagnostic accuracy, the quality of image manipulations such as registration and segmentation, and…”
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Towards the scale up of tissue engineered intervertebral discs for clinical application by Gullbrand, Sarah E., Kim, Dong Hwa, Bonnevie, Edward, Ashinsky, Beth G., Smith, Lachlan J., Elliott, Dawn M., Mauck, Robert L., Smith, Harvey E.

“…[Display omitted] Replacement of the intervertebral disc with a viable, tissue-engineered construct that mimics native tissue structure and function is an…”
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The subacromial bursa modulates tendon healing after rotator cuff injury in rats by Marshall, Brittany P, Ashinsky, Beth G, Ferrer, Xavier E, Kunes, Jennifer A, Innis, Astia C, Luzzi, Andrew J, Forrester, Lynn Ann, Burt, Kevin G, Lee, Andy J, Song, Lee, Lisiewski, Lauren E, Soni, Rajesh K, Hung, Clark T, Levine, William N, Kovacevic, David, Thomopoulos, Stavros

“…Rotator cuff injuries result in more than 500,000 surgeries annually in the United States, many of which fail. These surgeries typically involve repair of the…”
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REPLY TO ROEMER AND GUERMAZI: Early biochemical changes on MRI can predict risk of symptomatic progression by Kundu, Shinjini, Ashinsky, Beth G., Bouhrara, Mustapha, Dam, Erik B., Demehri, Shadpour, Shifat-E-Rabbi, M., Spencer, Richard G., Urish, Kenneth L., Rohde, Gustavo K.

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Aberrant mechanosensing in injured intervertebral discs as a result of boundary-constraint disruption and residual-strain loss by Bonnevie, Edward D., Gullbrand, Sarah E., Ashinsky, Beth G., Tsinman, Tonia K., Elliott, Dawn M., Chao, Pen-hsiu Grace, Smith, Harvey E., Mauck, Robert L.

“…In fibrous tissues, prestressed boundary constraints at bone interfaces instil residual strain throughout the tissue, even when unloaded. For example, internal…”
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Multiscale and multimodal structure–function analysis of intervertebral disc degeneration in a rabbit model by Ashinsky, B.G., Gullbrand, S.E., Bonnevie, E.D., Mandalapu, S.A., Wang, C., Elliott, D.M., Han, L., Mauck, R.L., Smith, H.E.

“…The objective of this study was to perform a quantitative analysis of the structural and functional alterations in the intervertebral disc during in vivo…”
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