Search Results - "Ashford, Mark E."
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Synthesis and in vitro evaluation of tetrahydroisoquinolines with pendent aromatics as sigma-2 (σ2) selective ligands
Published in Organic & biomolecular chemistry (07-02-2014)“…5-Bromo-N-[4-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-butyl)]-2,3-dimethoxybenzamide 1 is a potent and selective σ2 receptor ligand suitable for further…”
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Evaluation of the antidepressant therapeutic potential of isocyanine and pseudoisocyanine analogues of the organic cation decynium-22
Published in European journal of medicinal chemistry (08-09-2017)“…Herein we describe the synthesis and evaluation of antidepressant properties of seven analogues (1–7) of the low affinity/high capacity transporter blocker…”
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Synthesis and in Vivo Evaluation of [123I]Melanin-Targeted Agents
Published in Journal of medicinal chemistry (13-08-2015)“…This study reports the synthesis, [123I]radiolabeling, and biological profile of a new series of iodinated compounds for potential translation to the…”
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