Search Results - "Ashendel, C. L."

Kinase Inhibitors from Polygonum cuspidatum by Jayatilake, Gamini S, Jayasuriya, Hiranthi, Lee, Eung-Seok, Koonchanok, Nuphavan M, Geahlen, Robert L, Ashendel, Curtis L, McLaughlin, Jerry L, Chang, Ching-Jer

“…Bioassay-directed fractionation of a medicinal plant, Polygonum cuspidatum (Polygonaceae), has led to the discovery of a hydroxystilbene, resveratrol [1], as…”
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Signaling through mitogen-activated protein kinase and Rac/Rho does not duplicate the effects of activated Ras on skeletal myogenesis by Ramocki, Melissa B., Johnson, Sally E., White, Michael A., Ashendel, Curtis L., Konieczny, Stephen F., Taparowsky, Elizabeth J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Novel protein kinase C inhibitors: α-terthiophene derivatives by Kim, Darrick S.H.L., Ashendel, Curtis L., Zhou, Qin, Chang, Ching-te, Lee, Eung-Seok, Chang, Ching-jer

“…A series of α-terthiophene derivatives were prepared and their protein kinase C inhibitory activity were evaluated. The aldehyde derivatives were most potent…”
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Novel protein kinase C inhibitors: synthesis and PKC inhibition of β-substituted polythiophene derivatives by Xu, Wei-Chu, Zhou, Qin, Ashendel, Curtis L., Chang, Ching-te, Chang, Ching-jer

“…A series of β-substituted polythiophene derivatives was synthesized through palladium-catalyzed coupling reaction. Their structure-protein kinase C (PKC)…”
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Workgroup 3: Transgenic and reconstitution models of prostate cancer by Green, Jeffrey E., Greenberg, Norman M., Ashendel, Curtis L., Barrett, J. Carl, Boone, Charles, Getzenberg, Robert H., Henkin, Jack, Matusik, Robert, Janus, Todd J., Scher, Howard I.

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Differing modulation of protein kinase C by bryostatin 1 and phorbol esters in JB6 mouse epidermal cells by Kraft, A S, Reeves, J A, Ashendel, C L

“…Bryostatin 1 (Bryo), a macrocyclic lactone, stimulates some but not all of the biologic effects which are induced by phorbol esters (PEs). In vitro, it…”
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Diet, signal transduction and carcinogenesis by Ashendel, C L

“…The defects in the regulation of cell growth and differentiation that manifest themselves as cancer result from multiple defective genes and their products,…”
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The phorbol ester receptor: a phospholipid-regulated protein kinase by Ashendel, C L

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A multiwell assay for inhibitors of phosphatidylinositol-3-kinase and the identification of natural product inhibitors by Frew, T, Powis, G, Berggren, M, Abraham, R T, Ashendel, C L, Zalkow, L H, Hudson, C, Qazia, S, Gruszecka-Kowalik, E, Merriman, R

“…A convenient and reliable multisample assay for the screening of inhibitors of the growth factor signalling enzyme phosphatidylinositol-3-kinase (PtdIns-3-K)…”
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Oncogene signal transduction inhibitors from Chinese medicinal plants by Chang, C.-j., Ashendel, C. L., Chan, T. C. K., Geahlen, R. L., McLaughlin, Jerry, Waters, D. J.

“…Abstract…”
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Inhibition of Myogenesis by the H-ras Oncogene: Implication of a Role for Protein Kinase C by Vaidya, Tushar B., Weyman, Crystal M., Teegarden, Dorothy, Ashendel, Curtis L., Taparowsky, Elizabeth J.

“…Expression of the oncogenic form of H-ras p21 in the mouse myogenic cell line, 23A2, blocks myogenesis and inhibits expression of the myogenic regulatory…”
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Protein kinase activity associated with a phorbol ester receptor purified from mouse brain by ASHENDEL, C. L, STALLER, J. M, BOUTWELL, R. K

“…Protein kinase activity copurified with the receptor for 12-O-[3H]tetradecanoylphorbol-13-acetate during its purification from mouse brain particulate protein…”
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Inhibition of intracellular Ca2+ signalling, cytotoxicity and antitumor activity of the herbicide oryzalin and its analogues by POWIS, G, GALLEGOS, A, ABRAHAM, R. T, ASHENDEL, C. L, ZALKOW, L. H, DORR, R, DVORAKOVA, K, SALMON, S, HARRISON, S, WORZALLA, J

“…Studies were conducted on oryzalin (3,5-dinitro-N,N-di(n-propyl)sulfanilamide), a widely used dinitroaniline sulfonamide herbicide, which was identified from…”
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Hemicholinium and related lipids: inhibitors of protein kinase C by Kumaravel, G., Ashendel, Curtis L., Gandour, Richard D.

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Novel quinone antiproliferative inhibitors of phosphatidylinositol-3-kinase by Frew, T, Powis, G, Berggren, M, Gallegos, A, Abraham, R T, Ashendel, C L, Zalkow, L H, Hudson, C, Gruszecka-Kowalik, E, Burgess, E M

“…The inhibition of phosphatidylinositol-3-kinase (PtdIns-3-kinase), protein kinase C and c-Src protein tyrosine kinase by a series of halogenated…”
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Isolation of cloned mouse protein kinase C beta-II cDNA and its sequence by YONG-MING TANG, ASHENDEL, C. L

“…We have utilized synthetic oligonucleotides based on the sequences of rat protein kinase C (PKC)- beta and rat PKC- gamma to isolate cloned cDNA from a…”
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Increased intracellular Ca2+ signaling caused by the antitumor agent helenalin and its analogues by POWIS, G, GALLEGOS, A, ABRAHAM, R. T, ASHENDEL, C. L, ZALKOW, L. H, GRINDEY, G. B, BONJOUKLIAN, R

“…The antitumor sesquiterpene lactone helenalin, which is found in species of the plant genus Helenium, caused a marked potentiation of the increases in…”
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Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk by Furlong, Michael T, Mahrenholz, Alan M, Kim, Ki-Han, Ashendel, Curtis L, Harrison, Marietta L, Geahlen, Robert L

“…The protein tyrosine kinase p72 syk (Syk) is expressed in a variety of hematopoietic cell types, including B cells, thymocytes, mast cells and others. Both the…”
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A multisample assay for inhibitors of phosphatidylinositol phospholipase C: identification of naturally occurring peptide inhibitors with antiproliferative activity by Hill, S R, Bonjouklian, R, Powis, G, Abraham, R T, Ashendel, C L, Zalkow, L H

“…A convenient and reliable multisample assay for the screening of inhibitors of the growth factor signalling enzyme phosphatidylinositol specific phospholipase…”
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Mechanism of phorbol ester activation of calcium-activated, phospholipid-dependent protein kinase by Ashendel, C L, Minor, P L

“…Tumor-promoting phorbol esters activated a calcium-activated, phospholipid-dependent protein kinase by direct complexation with this protein kinase and…”
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