Search Results - "Ashcroft, R"

Ethics and social acceptability of a proposed clinical trial using maternal gene therapy to treat severe early‐onset fetal growth restriction by Sheppard, M., Spencer, R. N., Ashcroft, R., David, A. L., Ambler, Gareth, Brodszki, Jana, Campbell, David, Diemert, Anke, Figueras, Francesc, Hansson, Stefan, Hecher, Kurt, Huertas‐Ceballos, Angela, Lees, Mark, Ley, David, Marlow, Neil, Marsal, Karel, Martin, John, Morsing, Eva, Peebles, Donald M., Sebire, Neil, Zachary, Ian

“…ABSTRACT Objective To evaluate the ethical and social acceptability of a proposed clinical trial using maternal uterine artery vascular endothelial growth…”
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Protocol for a cluster randomised control trial evaluating the efficacy and safety of treatment for latent tuberculosis infection in recent migrants within primary care: the CATAPuLT trial by Burman, M, Copas, A, Zenner, D, Hickson, V, Gosce, L, Trathen, D, Ashcroft, R, Martineau, A R, Abubakar, I, Griffiths, C, Kunst, H

“…The identification and treatment of LTBI is a key component of the WHO's strategy to eliminate TB. Recent migrants from high TB-incidence countries are…”
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Building an Opt-Out Model for Service-Level Consent in the Context of New Data Regulations by Howarth, A R, Estcourt, C S, Ashcroft, R E, Cassell, J A

“…The General Data Protection Regulation (GDPR) was introduced in 2018 to harmonize data privacy and security laws across the European Union (EU). It applies to…”
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Current epistemological problems in evidence based medicine by Ashcroft, R E

“…Evidence based medicine has been a topic of considerable controversy in medical and health care circles over its short lifetime, because of the claims made by…”
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Interventions for improving patients' trust in doctors and groups of doctors by McKinstry, B, Ashcroft, R E, Car, J, Freeman, G K, Sheikh, A

“…Trust is a fundamental component of the patient-doctor relationship and is associated with increased satisfaction, adherence to treatment, and continuity of…”
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The ethics of mandatory vaccination against influenza for health care workers by van Delden, J.J.M, Ashcroft, R, Dawson, A, Marckmann, G, Upshur, R, Verweij, M.F

“…Abstract Vaccination of health care workers (HCW) in long-term care results in indirect protection of patients who are at high-risk for influenza. The…”
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Ethical review of research into rare genetic disorders by Parker, M, Ashcroft, R, Wilkie, A O M, Kent, A

“…Although some work on rare diseases is clearly clinical investigation and some clearly research, much activity falls uneasily between the two. Where should we…”
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Clinician and service user perceptions of implementing contingency management: A focus group study by Sinclair, J.M.A, Burton, A, Ashcroft, R, Priebe, S

“…Abstract Background Contingency management (CM), despite the evidence base for its effectiveness, remains controversial, with sub-optimal implementation. In…”
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The ethics of reusing archived tissue for research by Ashcroft, R.

“…Pathologists have been establishing archives of human organs and tissue for research use for many years now. Controversy has arisen recently over these…”
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Whole-Genome Analysis of 60 G Protein-Coupled Receptors in Caenorhabditis elegans by Gene Knockout with RNAi by Keating, Christopher D., Kriek, Neline, Daniels, Margaret, Ashcroft, Neville R., Hopper, Neil A., Siney, Elodie J., Holden-Dye, Lindy, Burke, Julian F.

“…G protein-coupled receptors (GPCRs) are the largest family of genes in animal genomes and represent more than 2% of genes in humans and C. elegans. These…”
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Are meticillin-resistant Staphylococcus aureus bloodstream infection targets fair to those with other types of healthcare-associated infection or cost-effective? by Millar, M, Coast, J, Ashcroft, R

“…Summary UK National Health Service Trust hospitals are required to report meticillin-resistant Staphylococcus aureus bloodstream infection (MRSA BSI) and also…”
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Giving medicine a fair trial by Ashcroft, Richard

“…All the weight in this argument depends on the nature of the uncertainty. And this uncertainty is essentially relative, on the one hand to a body of existing…”
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Point-of-care HIV testing in primary care and early detection of HIV (RHIVA2): a cluster randomised controlled trial by Leber, W, Dr, McMullen, H, MSc, Marlin, N, MSc, Bremner, S, PhD, Santos, AC, PhD, Terris-Prestholt, F, PhD, Boomla, K, MSc, Ashcroft, R, Prof, Kerry, S, MSc, Martineau, A, PhD, Millett, D, MSc, Mguni, S, MSc, Creighton, S, MBBS, Hart, G, Prof, Figueroa, J, PhD, Anderson, J, Prof, Griffiths, C, Prof

“…Abstract Background Early HIV detection in primary care is a key challenge. We completed a cluster randomised controlled trial in UK general practices to…”
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Treatment Refractory Soft Tissue Myoepithelial Carcinoma With an ARID1A Mutation by Ashcroft, Cody R., Penney, Scott W., Whiteway, Susan L.

“…Soft tissue myoepithelial carcinoma is a rare tumor first reported in the salivary gland. There is considerable tumor heterogeneity between pathology findings,…”
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Further ethical and social issues in using a cocaine vaccine: response to Hall and Carter by Ashcroft, R E, Franey, C

“…Evaluation of the potential of a cocaine vaccine requires a detailed understanding of the intended and unintended social consequences of its use. Prospective…”
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Making sense of dignity by Ashcroft, Richard E

“…In this review of Leon Kass’s Life, liberty and the defense of dignity and Deryck Beyleveld and Roger Brownsword’s Human dignity in bioethics and biolaw. I…”
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Responsibilities of sponsors are limited in premature discontinuation of trials by Ashcroft, Richard

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Ethics behind closed doors: do research ethics committees need secrecy? by Ashcroft, Richard, Pfeffer, Naomi

“…Doctors have a duty of confidentiality to their patients, but this is normally irrelevant to research ethics committees. Patient information will be relevant…”
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Ethics, philosophy, and evidence based medicine by Ashcroft, R, ter Meulen, R

“…Since Sir Archie Cochrane's seminal Nuffield Provincial Hospitals Trust lectures in 1972 and their publication as the Rock Carling monograph for that year,…”
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American biofutures: ideology and utopia in the Fukuyama/Stock debate by Ashcroft, R E

“…Francis Fukuyama, in his Our Posthuman Future, and Gregory Stock, in his Redesigning Humans, present competing versions of the biomedical future of human…”
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