Search Results - "Ashby, Emma L"

Pathophysiology of white matter perfusion in Alzheimer’s disease and vascular dementia by Barker, Rachel, Ashby, Emma L., Wellington, Dannielle, Barrow, Vivienne M., Palmer, Jennifer C., Kehoe, Patrick G., Esiri, Margaret M., Love, Seth

“…The pathophysiology of white matter hypoperfusion is poorly understood. Barker et al. quantify ante-mortem hypoperfusion by measuring myelin proteins…”
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Effects of Hypertension and Anti-Hypertensive Treatment on Amyloid-β (Aβ) Plaque Load and Aβ-Synthesizing and Aβ-Degrading Enzymes in Frontal Cortex by Ashby, Emma L, Miners, James S, Kehoe, Patrick G, Love, Seth

“…Epidemiological data associate hypertension with a predisposition to Alzheimer's disease (AD), and a number of postmortem and in vivo studies also demonstrate…”
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Assessment of activation of the plasma kallikrein-kinin system in frontal and temporal cortex in Alzheimer's disease and vascular dementia by Ashby, Emma L, Love, Seth, Kehoe, Patrick G

“…Abstract Decreased cerebral blood flow and blood-brain barrier disruption are features of Alzheimer's disease (AD). The plasma kallikrein-kinin system…”
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Altered Expression of Human Mitochondrial Branched Chain Aminotransferase in Dementia with Lewy Bodies and Vascular Dementia by Ashby, Emma L., Kierzkowska, Marta, Hull, Jonathon, Kehoe, Patrick G., Hutson, Susan M., Conway, Myra E.

“…Cytosolic and mitochondrial human branched chain aminotransferase (hBCATc and hBCATm, respectively) play an integral role in brain glutamate metabolism…”
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Kallikrein-related peptidase 6 in Alzheimer's disease and vascular dementia by Ashby, Emma L, Kehoe, Patrick G, Love, Seth

“…Abstract Human kallikrein-related peptidase 6 (KLK6) is highly expressed in the central nervous system. Although the physiological roles of this serine…”
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Investigation of Aβ phosphorylated at serine 8 (pAβ) in Alzheimer's disease, dementia with Lewy bodies and vascular dementia by Ashby, Emma L., Miners, James S., Kumar, Sathish, Walter, Jochen, Love, Seth, Kehoe, Patrick G.

“…Aims Deposition of amyloid beta (Aβ) in the brain is one of the defining abnormalities of Alzheimer's disease (AD). Phosphorylation of Aβ at serine 8 (pAβ) has…”
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The association of angiotensin-converting enzyme with biomarkers for Alzheimer's disease by Jochemsen, Hadassa M, Teunissen, Charlotte E, Ashby, Emma L, van der Flier, Wiesje M, Jones, Ruth E, Geerlings, Mirjam I, Scheltens, Philip, Kehoe, Patrick G, Muller, Majon

“…Lower angiotensin-converting enzyme (ACE) activity could increase the risk of Alzheimer's disease (AD) as ACE functions to degrade amyloid-β (Aβ). Therefore,…”
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Angiotensin-converting enzyme in cerebrospinal fluid and risk of brain atrophy by Jochemsen, Hadassa M, van der Flier, Wiesje M, Ashby, Emma L, Teunissen, Charlotte E, Jones, Ruth E, Wattjes, Mike P, Scheltens, Philip, Geerlings, Mirjam I, Kehoe, Patrick G, Muller, Majon

“…Higher angiotensin-converting enzyme (ACE) activity might increase the risk of Alzheimer's disease by increasing blood pressure, and subsequent development of…”
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Investigation of A β phosphorylated at serine 8 (p A β) in A lzheimer's disease, dementia with L ewy bodies and vascular dementia by Ashby, Emma L., Miners, James S., Kumar, Sathish, Walter, Jochen, Love, Seth, Kehoe, Patrick G.

“…Aims Deposition of amyloid beta ( A β) in the brain is one of the defining abnormalities of A lzheimer's disease ( AD ). Phosphorylation of A β at serine 8 (p…”
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Investigation of A[beta] phosphorylated at serine 8 (pA[beta]) in Alzheimer's disease, dementia with Lewy bodies and vascular dementia by Ashby, Emma L, Miners, James S, Kumar, Sathish, Walter, Jochen, Love, Seth, Kehoe, Patrick G

“…Aims Deposition of amyloid beta (A[beta]) in the brain is one of the defining abnormalities of Alzheimer's disease (AD). Phosphorylation of A[beta] at serine 8…”
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