Search Results - "Asgharzadeh, Fereshteh"
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The Role of Heat Shock Protein 40 in Carcinogenesis and Biology of Colorectal Cancer
Published in Current pharmaceutical design (01-01-2022)“…Colorectal cancer (CRC) is the third most common cancer worldwide. Despite the enormous amount of effort in the diagnosis and treatment of CRC, the overall…”
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The Role of Heat Shock Protein 27 in Carcinogenesis and Treatment of Colorectal Cancer
Published in Current pharmaceutical design (01-01-2022)“…The incidence of colorectal cancer (CRC) has significantly increased in recent decades, which has made this disease an important global health issue. Despite…”
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The Clinical Impact of Quantitative Cell-free DNA, KRAS, and BRAF Mutations on Response to Anti-EGFR Treatment in Patients with Metastatic Colorectal Cancer
Published in Current pharmaceutical design (01-01-2021)“…Colorectal cancer (CRC) is one of the most common leading causes of cancer death in the world. Although EGFR inhibitors have established efficacy in metastatic…”
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4
EW‐7197 prevents ulcerative colitis‐associated fibrosis and inflammation
Published in Journal of cellular physiology (01-07-2019)“…EW‐7197 is a transforming growth factor‐β type I receptor kinase inhibitor with potential anti‐inflammatory and antifibrotic properties. Here, we investigate…”
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Peroxisome proliferator-activated receptors: Key regulators of tumor progression and growth
Published in Translational oncology (01-09-2024)“…•PPARs have a vital role in the proliferation, survival, and apoptosis of cancer cell.•PPAR modulators are potential targets for cancer treatment.•PPARs have…”
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Mebendazole, an anti-helminth drug, suppresses inflammation, oxidative stress and injury in a mouse model of ulcerative colitis
Published in Scientific reports (17-06-2022)“…Mebendazole (MBZ) is an efficacious anthelmintic with known anti-inflammatory and fibrinolytic properties. In this study, we aimed to explore the protective…”
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Renin-angiotensin System Inhibitors and Development of Hepatocellular Carcinoma: A Systematic Review and Meta-analysis
Published in Current pharmaceutical design (01-01-2020)“…There are controversial results available about using angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) and the…”
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Oenothera biennis improves pregnancy outcomes by suppressing inflammation and fibrosis in an intra-uterine adhesion rat model
Published in Scientific reports (27-09-2024)“…Intrauterine adhesion (IUA), also referred to as Asherman’s syndrome, is characterized by fibrosis, inflammation, and can cause amenorrhea and infertility due…”
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Targeting transforming growth factor beta (TGF-β) using Pirfenidone, a potential repurposing therapeutic strategy in colorectal cancer
Published in Scientific reports (01-09-2023)“…The modulating factors within the tumor microenvironment, for example, transforming growth factor beta (TGF-β), may limit the response to chemo and…”
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Anticancer activity of Helicobacter pylori ribosomal protein (HPRP) with iRGD in treatment of colon cancer
Published in Journal of cancer research and clinical oncology (01-10-2021)“…Purpose As the conventional therapeutic approaches were not completely successful in the treatment of colon cancer, there is still a need for finding the most…”
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Angiotensin-converting Enzyme Inhibitors and Angiotensin Receptor Blockers as Potential Therapeutic Options for Pancreatic Cancer
Published in Current cancer drug targets (01-01-2022)“…The renin-angiotensin system (RAS) has been reported to have a role in carcinogenesis, and therefore it may be of value as a potential therapeutic target in…”
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Vactosertib potently improves anti-tumor properties of 5-FU for colon cancer
Published in Daru (23-09-2023)“…Background Several studies have shown that the TGF-β signaling pathway plays a critical role in colorectal cancer (CRC) pathogenesis. The aim of the current…”
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Effect of renin-angiotensin system inhibitors on survival rate of patients with breast cancer: systematic review and meta-analysis
Published in Majallāh-i zanān-i mamāʼī va nāzāʼī-i Īrān (01-08-2020)“…Introduction: Breast cancer is one of the most common cancers and the second leading cause of cancer deaths among women worldwide. There is direct relationship…”
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Thymoquinone protects the rat kidneys against renal fibrosis
Published in Research in pharmaceutical sciences (01-12-2017)“…Thymoquinone (TQ) is the main active ingredient of Nigella sativa seeds with various pharmacological effects. The aim of this study was to investigate the…”
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Fabrication and application of cisplatin-loaded mesoporous magnetic nanobiocomposite: a novel approach to smart cervical cancer chemotherapy
Published in Cancer nanotechnology (01-12-2022)“…There are significant challenges in developing drug carriers for therapeutic perspective. We have investigated a novel nanocarrier system, based on combining…”
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Effect of angiotensin-converting enzyme inhibitor on cardiac fibrosis and oxidative stress status in lipopolysaccharide-induced inflammation model in rats
Published in International journal of preventive medicine (01-01-2017)“…Background: Renin-angiotensin (Ang)-aldosterone system not only plays a key role in the regulation of circulatory homeostasis, but also it acts as a powerful…”
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Thymoquinone Prevents Myocardial and Perivascular Fibrosis Induced by Chronic Lipopolysaccharide Exposure in Male Rats: - Thymoquinone and Cardiac Fibrosis
Published in Journal of pharmacopuncture (01-12-2018)“…Thymoquinone (TQ) is one of the active ingredients of herbal plants such as Nigella sativa L. (NS) which has beneficial effects on the body. The beneficial…”
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Cardiac and renal fibrosis and oxidative stress balance in lipopolysaccharide-induced inflammation in male rats
Published in ARYA atherosclerosis (01-03-2018)“…Subclinical inflammation induced by persistent exposure to lipopolysaccharide (LPS) is found in some clinical conditions such as obesity or diabetes. This…”
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Two-dimensional-Ti3C2 magnetic nanocomposite for targeted cancer chemotherapy
Published in Frontiers in bioengineering and biotechnology (25-01-2023)“…Introduction: Cervical cancer is the leading cause of cancer-related death in women, so novel therapeutic approaches are needed to improve the effectiveness of…”
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The therapeutic potential of angiotensin-converting enzyme inhibitor enalapril to ameliorate muscle atrophy in a murine model
Published in EXCLI journal (01-01-2024)“…Muscle atrophy due to limb immobilization and inactivity is a common consequence of many diseases and treatment processes. One of the systems activated in…”
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