Search Results - "Ascough, David M. H."

Asymmetric nucleophilic fluorination under hydrogen bonding phase-transfer catalysis by Pupo, Gabriele, Ibba, Francesco, Ascough, David M H, Vicini, Anna Chiara, Ricci, Paolo, Christensen, Kirsten E, Pfeifer, Lukas, Morphy, John Richard, Brown, John M, Paton, Robert S, Gouverneur, Véronique

“…Common anionic nucleophiles such as those derived from inorganic salts have not been used for enantioselective catalysis because of their insolubility. Here,…”
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Hydrogen Bonding Phase-Transfer Catalysis with Potassium Fluoride: Enantioselective Synthesis of β‑Fluoroamines by Pupo, Gabriele, Vicini, Anna Chiara, Ascough, David M. H, Ibba, Francesco, Christensen, Kirsten E, Thompson, Amber L, Brown, John M, Paton, Robert S, Gouverneur, Véronique

“…Potassium fluoride (KF) is an ideal reagent for fluorination because it is safe, easy to handle and low-cost. However, poor solubility in organic solvents…”
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Stereospecific 1,3‑H Transfer of Indenols Proceeds via Persistent Ion-Pairs Anchored by NH···π Interactions by Ascough, David M. H, Duarte, Fernanda, Paton, Robert S

“…The base-catalyzed rearrangement of arylindenols is a rare example of a suprafacial [1,3]-hydrogen atom transfer. The mechanism has been proposed to proceed…”
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Hydrogen Bonding Phase-Transfer Catalysis with Ionic Reactants: Enantioselective Synthesis of γ‑Fluoroamines by Roagna, Giulia, Ascough, David M. H, Ibba, Francesco, Vicini, Anna Chiara, Fontana, Alberto, Christensen, Kirsten E, Peschiulli, Aldo, Oehlrich, Daniel, Misale, Antonio, Trabanco, Andrés A, Paton, Robert S, Pupo, Gabriele, Gouverneur, Véronique

“…Ammonium salts are used as phase-transfer catalysts for fluorination with alkali metal fluorides. We now demonstrate that these organic salts, specifically…”
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Chemical Epigenetics: The Impact of Chemical and Chemical Biology Techniques on Bromodomain Target Validation by Schiedel, Matthias, Moroglu, Mustafa, Ascough, David M. H., Chamberlain, Anna E. R., Kamps, Jos J. A. G., Sekirnik, Angelina R., Conway, Stuart J.

“…Epigenetics is currently the focus of intense research interest across a broad range of disciplines due to its importance in a multitude of biological…”
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Data-mining the diaryl(thio)urea conformational landscape: Understanding the contrasting behavior of ureas and thioureas with quantum chemistry by Luchini, Guilian, Ascough, David M.H., Alegre-Requena, Juan V., Gouverneur, Veronique, Paton, Robert S.

“…The conformations adopted by urea and thiourea functional groups influence catalysis and binding. We combine data-mining with quantum chemical calculations to…”
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Enantioselective rhodium-catalysed insertion of trifluorodiazoethanes into tin hydrides by Hyde, Stephen, Veliks, Janis, Ascough, David M.H., Szpera, Robert, Paton, Robert S., Gouverneur, Véronique

“…Aryl substituted 2,2,2-trifluorodiazoethanes undergo rhodium(II)-catalysed insertion reactions with tin hydrides affording the corresponding…”
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Chemische Epigenetik: der Einfluss chemischer und chemo‐biologischer Techniken auf die Zielstruktur‐Validierung von Bromodomänen by Schiedel, Matthias, Moroglu, Mustafa, Ascough, David M H, Chamberlain, Anna E R, Jos J A G Kamps, Sekirnik, Angelina R, Conway, Stuart J

“…Viele Disziplinen befassen sich gegenwärtig mit Epigenetik, da diese von Bedeutung für viele biologische Vorgänge und pathologische Zustände ist. Auf…”
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Chemische Epigenetik: der Einfluss chemischer und chemo‐biologischer Techniken auf die Zielstruktur‐Validierung von Bromodomänen by Schiedel, Matthias, Moroglu, Mustafa, Ascough, David M. H., Chamberlain, Anna E. R., Kamps, Jos J. A. G., Sekirnik, Angelina R., Conway, Stuart J.

“…Viele Disziplinen befassen sich gegenwärtig mit Epigenetik, da diese von Bedeutung für viele biologische Vorgänge und pathologische Zustände ist. Auf…”
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