Search Results - "Aschner, J."
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NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets
Published in American journal of physiology. Lung cellular and molecular physiology (01-10-2009)“…Recently, we reported that reactive oxygen species (ROS) generated by NADPH oxidase (NOX) contribute to aberrant responses in pulmonary resistance arteries…”
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Impact of the COVID-19 pandemic on children’s sleep habits: an ECHO study
Published in Pediatric research (01-02-2023)“…Background Sleep in childhood is affected by behavioral, environmental, and parental factors. We propose that these factors were altered during the COVID-19…”
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3
Management of hypoxemic respiratory failure and pulmonary hypertension in preterm infants
Published in Journal of perinatology (01-06-2016)“…While diagnoses of hypoxemic respiratory failure (HRF) and pulmonary hypertension (PH) in preterm infants may be based on criteria similar to those in term…”
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Increasing F2-isoprostanes in the first month after birth predicts poor respiratory and neurodevelopmental outcomes in very preterm infants
Published in Journal of perinatology (01-09-2016)“…Objective: This study examined the association between increased early oxidative stress, measured by F2-isoprostanes (IsoPs), and respiratory morbidity at term…”
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Challenges, priorities and novel therapies for hypoxemic respiratory failure and pulmonary hypertension in the neonate
Published in Journal of perinatology (01-06-2016)“…Future priorities for the management of hypoxemic respiratory failure (HRF) and pulmonary hypertension include primary prevention of neonatal lung diseases,…”
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The role for saxagliptin within the management of type 2 diabetes mellitus: an update from the 2010 European Association for the Study of Diabetes (EASD) 46th annual meeting and the American Diabetes Association (ADA) 70th scientific session
Published in Diabetology and metabolic syndrome (15-12-2010)“…Saxagliptin is a potent, selective DPP4 inhibitor. Highlights from abstracts presented at the 2010 meetings of the European Association for the Study of…”
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Interactions between excessive manganese exposures and dietary iron-deficiency in neurodegeneration
Published in Environmental toxicology and pharmacology (01-05-2005)“…For nearly a century, manganese has been recognized as an essential nutrient for proper bone formation, lipid, amino acid and carbohydrate metabolism. While…”
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Manganese neurotoxicity: cellular effects and blood-brain barrier transport
Published in Neuroscience and biobehavioral reviews (1991)“…The observations by Couper in 1837 are acknowledged as the earliest description of the toxic syndrome associated with chronic manganese (Mn) exposure. Since…”
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Metabolic memory for vascular disease in diabetes
Published in Diabetes technology & therapeutics (01-06-2012)“…Although the terms "metabolic memory" and "legacy effect" have been used to describe the prolonged benefits of good blood glucose control, the former is now…”
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Estudio IDEA (International Day for Evaluation of Abdominal Obesity): prevalencia de obesidad abdominal y factores de riesgo asociados en atención primaria en Colombia
Published in Biomédica (01-12-2012)“…Introducción. La obesidad está asociada con factores de riesgo para enfermedades cardiovasculares y metabólicas. La obesidad central, marcador de adiposidad…”
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Mercury neurotoxicity: mechanisms of blood-brain barrier transport
Published in Neuroscience and biobehavioral reviews (1990)“…Mercury exists in a wide variety of physical and chemical states, each of which has unique characteristics of target organ toxicity. The classic symptoms…”
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Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes
Published in Brain research. Molecular brain research. (13-06-2005)“…Excessive free radical formation has been implicated as one of the causative factors in neurotoxic damage associated with variety of metals, including…”
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13
Effect of Flow Rate and Insulin Priming on the Recovery of Insulin From Microbore Infusion Tubing
Published in Pediatrics (Evanston) (01-12-1998)“…A retrospective medical record review of 13 consecutive, hyperglycemic, extremely low birth weight (ELBW) infants treated with continuous insulin infusions…”
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Manganese transport across the blood-brain barrier: relationship to iron homeostasis
Published in Brain research bulletin (01-06-1990)“…The binding characteristics of manganese (Mn) to transferrin (Tf) were examined on G-75 Sephadex gel columns. When 54MnCl2 was combined with Tf and immediately…”
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Cellular and molecular effects of trimethyltin and triethyltin: relevance to organotin neurotoxicity
Published in Neuroscience and biobehavioral reviews (1992)“…Many of the neurotoxic aspects of organotin exposure have been described. Organotin exposure culminates in its accumulation in the CNS and PNS. The clinical…”
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Racial differences in selected cytokine allelic and genotypic frequencies among healthy, pregnant women in North Carolina
Published in Cytokine (Philadelphia, Pa.) (07-01-2003)“…Background: Genetic susceptibility to diseases is likely influenced by common DNA variants in the form of single nucleotide polymorphisms (SNPs). The value of…”
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Methylmercury Neurotoxicity: Exploring Potential Novel Targets
Published in The open toxicology journal (01-01-2007)“…Mechanistic studies on the effects of MeHg in the central nervous system (CNS) have been limited to morphology, substrate uptake and macromolecular synthesis,…”
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Characteristics of manganese (Mn) transport in rat brain endothelial (RBE4) cells, an in vitro model of the blood–brain barrier
Published in Neurotoxicology (Park Forest South) (2006)“…Manganese (Mn), an essential elemental nutrient, is known to be neurotoxic at high occupational levels. We examined the transport of Mn across a monolayer of…”
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A review of maternal prenatal exposures to environmental chemicals and psychosocial stressors—implications for research on perinatal outcomes in the ECHO program
Published in Journal of perinatology (01-01-2020)“…Exposures to environmental chemicals and psychosocial stressors during pregnancy have been individually associated with adverse perinatal outcomes related to…”
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Incidence rates of childhood asthma with recurrent exacerbations in the US Environmental influences on Child Health Outcomes (ECHO) program
Published in Journal of allergy and clinical immunology (01-07-2023)“…[Display omitted] Descriptive epidemiological data on incidence rates (IRs) of asthma with recurrent exacerbations (ARE) are sparse. This study hypothesized…”
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