Search Results - "Ascensión, Alex M."

Human Dermal Fibroblast Subpopulations Are Conserved across Single-Cell RNA Sequencing Studies by Ascensión, Alex M., Fuertes-Álvarez, Sandra, Ibañez-Solé, Olga, Izeta, Ander, Araúzo-Bravo, Marcos J.

“…On the basis of their differential location within the dermis and of discrete changes in gene and protein expression, two major fibroblast subtypes (papillary…”
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Lack of evidence for increased transcriptional noise in aged tissues by Ibañez-Solé, Olga, Ascensión, Alex M, Araúzo-Bravo, Marcos J, Izeta, Ander

“…Aging is often associated with a loss of cell type identity that results in an increase in transcriptional noise in aged tissues. If this phenomenon reflects a…”
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Inflammation-mediated fibroblast activation and immune dysregulation in collagen VII-deficient skin by Anderson-Crannage, Morgan, Ascensión, Alex M., Ibanez-Solé, Olga, Zhu, Hongwen, Schaefer, Edo, Ottomanelli, Darcy, Hochberg, Bruno, Pan, Jian, Luo, Wen, Tian, Meijuan, Chu, Yaya, Cairo, Mitchell S., Izeta, Ander, Liao, Yanling

“…Inflammation is known to play a critical role in all stages of tumorigenesis; however, less is known about how it predisposes the tissue microenvironment…”
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HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis by Palomo-Irigoyen, Marta, Pérez-Andrés, Encarni, Iruarrizaga-Lejarreta, Marta, Barreira-Manrique, Adrián, Tamayo-Caro, Miguel, Vila-Vecilla, Laura, Moreno-Cugnon, Leire, Beitia, Nagore, Medrano, Daniela, Fernández-Ramos, David, Lozano, Juan José, Okawa, Satoshi, Lavín, José L, Martín-Martín, Natalia, Sutherland, James D, de Juan, Virginia Guitiérez, Gonzalez-Lopez, Monika, Macías-Cámara, Nuria, Mosén-Ansorena, David, Laraba, Liyam, Hanemann, C Oliver, Ercolano, Emanuela, Parkinson, David B, Schultz, Christopher W, Araúzo-Bravo, Marcos J, Ascensión, Alex M, Gerovska, Daniela, Iribar, Haizea, Izeta, Ander, Pytel, Peter, Krastel, Philipp, Provenzani, Alessandro, Seneci, Pierfausto, Carrasco, Ruben D, Del Sol, Antonio, Martinez-Chantar, María Luz, Barrio, Rosa, Serra, Eduard, Lazaro, Conxi, Flanagan, Adrienne M, Gorospe, Myriam, Ratner, Nancy, Aransay, Ana M, Carracedo, Arkaitz, Varela-Rey, Marta, Woodhoo, Ashwin

“…Cancer cells can develop a strong addiction to discrete molecular regulators, which control the aberrant gene expression programs that drive and maintain the…”
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Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes by Rodriguez, Ramon M., Suarez-Alvarez, Beatriz, Lavín, Jose L., Ascensión, Alex M., Gonzalez, Monika, Lozano, Juan J., Raneros, Aroa B., Bulnes, Paula D., Vidal-Castiñeira, Jose R., Huidobro, Covadonga, Martin-Martin, Cristina, Sanz, Ana B., Ruiz-Ortega, Marta, Puig-Kröger, Amaya, Corbí, Angel L., Araúzo-Bravo, Marcos J., Aransay, Ana M., Lopez-Larrea, Carlos

“…In recent years, the macrophage colony-stimulating factor (M-CSF) and granulocyte-macrophage CSF (GM-CSF) cytokines have been identified as opposing regulators…”
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NaviSE: superenhancer navigator integrating epigenomics signal algebra by Ascensión, Alex M, Arrospide-Elgarresta, Mikel, Izeta, Ander, Araúzo-Bravo, Marcos J

“…Superenhancers are crucial structural genomic elements determining cell fate, and they are also involved in the determination of several diseases, such as…”
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Challenges and Opportunities for the Translation of Single-Cell RNA Sequencing Technologies to Dermatology by Ascensión, Alex M, Araúzo-Bravo, Marcos J, Izeta, Ander

“…Skin is a complex and heterogeneous organ at the cellular level. This complexity is beginning to be understood through the application of single-cell genomics…”
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Triku: a feature selection method based on nearest neighbors for single-cell data by M Ascensión, Alex, Ibáñez-Solé, Olga, Inza, Iñaki, Izeta, Ander, Araúzo-Bravo, Marcos J

“…Abstract Background Feature selection is a relevant step in the analysis of single-cell RNA sequencing datasets. Most of the current feature selection methods…”
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The need to reassess single-cell RNA sequencing datasets: the importance of biological sample processing [version 2; peer review: 2 approved] by Ascensión, Alex M, Araúzo-Bravo, Marcos J, Izeta, Ander

“…Background: The advent of single-cell RNA sequencing (scRNAseq) and additional single-cell omics technologies have provided scientists with unprecedented tools…”
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FOntCell: Fusion of Ontologies of Cells by Cabau-Laporta, Javier, Ascensión, Alex M, Arrospide-Elgarresta, Mikel, Gerovska, Daniela, Araúzo-Bravo, Marcos J

“…High-throughput cell-data technologies such as single-cell RNA-seq create a demand for algorithms for automatic cell classification and characterization. There…”
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The need to reassess single-cell RNA sequencing datasets: more is not always better [version 1; peer review: 2 approved with reservations] by Ascensión, Alex M, Araúzo-Bravo, Marcos J, Izeta, Ander

“…Background: The advent of single-cell RNA sequencing (scRNAseq) and additional single-cell omics technologies have provided scientists with unprecedented tools…”
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BigMPI4py: Python Module for Parallelization of Big Data Objects Discloses Germ Layer Specific DNA Demethylation Motifs by Ascension, Alex M., Arauzo-Bravo, Marcos J.

“…Parallelization in Python integrates Message Passing Interface via the mpi4py module. Since mpi4py does not support parallelization of objects greater than…”
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