Search Results - "Asanuma, Miwako"
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Alkyne-Tag SERS Screening and Identification of Small-Molecule-Binding Sites in Protein
Published in Journal of the American Chemical Society (26-10-2016)“…Identification of small-molecule-binding sites in protein is important for drug discovery and analysis of protein function. Modified amino-acid residue(s) can…”
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2
Multiwell Raman plate reader for high-throughput biochemical screening
Published in Scientific reports (03-08-2021)“…Although Raman spectroscopy has been used for the quantitative analysis of samples in many fields, including material science, biomedical, and pharmaceutical…”
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Dual targeting of DDX3 and eIF4A by the translation inhibitor rocaglamide A
Published in Cell chemical biology (15-04-2021)“…The translation inhibitor rocaglamide A (RocA) has shown promising antitumor activity because it uniquely clamps eukaryotic initiation factor (eIF) 4A onto…”
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4
VDAC3 gating is activated by suppression of disulfide-bond formation between the N-terminal region and the bottom of the pore
Published in Biochimica et biophysica acta (01-12-2015)“…The voltage-dependent anion channels (VDACs), VDAC1, VDAC2, and VDAC3, are pore-forming proteins that control metabolite flux between mitochondria and…”
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5
Turn-ON fluorescent affinity labeling using a small bifunctional O-nitrobenzoxadiazole unit
Published in Chemical science (Cambridge) (2014)“…Affinity labeling has become a powerful tool to identify target proteins, as well as to visualize/characterize target functions in living cells. However,…”
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Identification of a Male-Specific RNA Binding Protein That Regulates Sex-Specific Splicing of Bmdsx by Increasing RNA Binding Activity of BmPSI
Published in Molecular and Cellular Biology (01-12-2010)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A "Catch-and-Release" Protocol for Alkyne-Tagged Molecules Based on a Resin-Bound Cobalt Complex for Peptide Enrichment in Aqueous Media
Published in Chemistry : a European journal (23-06-2014)“…The development of new and mild protocols for the specific enrichment of biomolecules is of significant interest from the perspective of chemical biology. A…”
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The Triacylated ATP Binding Cluster Transporter Substrate-binding Lipoprotein of Staphylococcus aureus Functions as a Native Ligand for Toll-like Receptor 2
Published in The Journal of biological chemistry (27-03-2009)“…Some synthetic lipopeptides, in addition to native lipoproteins derived from both Gram-negative bacteria and mycoplasmas, are known to activate TLR2 (Toll-like…”
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9
Protein phosphatase 1 positively regulates stomatal opening in response to blue light in Vicia faba
Published in Proceedings of the National Academy of Sciences - PNAS (05-09-2006)“…Phototropins, plant blue light receptors, mediate stomatal opening through the activation of the plasma membrane H⁺-ATPase by unknown mechanisms. Here we…”
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Catch and release of alkyne-tagged molecules in water by a polymer-supported cobalt complex
Published in Organic & biomolecular chemistry (26-10-2011)“…A cobalt-phosphine complex supported on PS-PEG beads was found to react with a propargyl carbamate tag, and the tagged molecules immobilized on the beads could…”
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Solution Structure of Vanabin2, a Vanadium(IV)-Binding Protein from the Vanadium-Rich Ascidian Ascidia sydneiensis samea
Published in Journal of the American Chemical Society (30-03-2005)“…Ascidians belonging to the suborder Phlebobranchia are known to accumulate high levels of a transition metal, vanadium, in their blood cells, called…”
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12
CDC25A-inhibitory RE derivatives bind to pocket adjacent to the catalytic site
Published in Molecular bioSystems (01-05-2013)“…RE derivatives, which are cell-permeable and non-electrophilic dual-specificity protein phosphatase inhibitors developed in our laboratory, inhibit CDC25A/B…”
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The effect of sodium dodecyl sulfate and anion-exchange silica gel on matrix-assisted laser desorption/ionization mass spectrometric analysis of proteins
Published in Rapid communications in mass spectrometry (15-06-2009)“…Sodium dodecyl sulfate (SDS), an anionic surfactant, is widely used in peptide and protein sample preparation. When the sample is analyzed by matrix‐assisted…”
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14
NTA-mediated protein capturing strategy in screening experiments for small organic molecules by surface plasmon resonance
Published in Proteomics (Weinheim) (01-02-2007)“…Nitrilotriacetate (NTA)‐mediated capture of a histidine‐tagged protein is widely used as an easy and simple method to reversibly immobilize the protein onto a…”
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15
Solid-state 17O NMR in Biological Solids: Efficient 17O Labeling of Amino Acids and Peptides
Published in Chemistry letters (01-01-2007)“…A highly effective labeling method for 17O-enriched amino acids and peptides at moderate experimental conditions (Japanese Patent 2006-8666) has been…”
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On-Probe Sample Preparation without Washes for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Using an Anion Exchange Medium
Published in Analytical chemistry (Washington) (01-09-2005)“…When the mass spectra of biological samples (proteins, peptides, and so on) are obtained routinely by matrix-assisted laser desorption/ionization mass…”
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17
Simple purification of small-molecule-labelled peptides via palladium enolate formation from β-ketoamide tags
Published in Chemical science (Cambridge) (09-08-2023)“…Palladium enolates derived from β-ketocarbonyl compounds serve as key intermediates in various catalytic asymmetric reactions. We found that the palladium…”
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Simple purification of small-molecule-labelled peptides palladium enolate formation from β-ketoamide tags
Published in Chemical science (Cambridge) (09-08-2023)“…Palladium enolates derived from β-ketocarbonyl compounds serve as key intermediates in various catalytic asymmetric reactions. We found that the palladium…”
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Solid-state 17O NMR Study of Small Biological Compounds
Published in Zeitschrift für Naturforschung. B, A journal of chemical sciences (01-11-2007)“…We present a systematic experimental and theoretical investigation of the oxygen chemical shielding and electric-field-gradient tensors in polycrystalline…”
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Solid-state 17O NMR study of the electric-field-gradient and chemical shielding tensors in polycrystalline amino acids
Published in Magnetic resonance in chemistry (01-07-2007)“…We have presented a systematic experimental investigation of carboxyl oxygen electric‐field‐gradient (EFG) and chemical shielding (CS) tensors in crystalline…”
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