Search Results - "Asakura, Kunihiko"

Amyloid-β hypothesis in Alzheimer's disease and neurotoxicity of oligomeric amyloid through glial cells by Asakura, Kunihiko

“…Abstract Amyloid hypothesis is considered to be the most feasible hypothesis for the pathogenesis of Alzheimer's disease ( AD ). Based on this hypothesis,…”
Get full text

MR neurography for the evaluation of CIDP by Ishikawa, Tomomasa, Asakura, Kunihiko, Mizutani, Yasuaki, Ueda, Akihiro, Murate, Ken‐Ichiro, Hikichi, Chika, Shima, Sayuri, Kizawa, Madoka, Komori, Masako, Murayama, Kazuhiro, Toyama, Hiroshi, Ito, Shinji, Mutoh, Tatsuro

“…ABSTRACT Introduction: To visualize peripheral nerves in patients with chronic inflammatory demyelinating polyneuropathy (CIDP), we used MR imaging. We also…”
Get full text

The wide spectrum of clinical manifestations in Sjögren's syndrome-associated neuropathy by Mori, Keiko, Iijima, Masahiro, Koike, Haruki, Hattori, Naoki, Tanaka, Fumiaki, Watanabe, Hirohisa, Katsuno, Masahisa, Fujita, Asako, Aiba, Ikuko, Ogata, Akihiko, Saito, Toyokazu, Asakura, Kunihiko, Yoshida, Mari, Hirayama, Masaaki, Sobue, Gen

“…We assessed the clinicopathological features of 92 patients with primary Sjögren's syndrome-associated neuropathy (76 women, 16 men, 54.7 years, age at onset)…”
Get full text

Phase II Trial of Intravenous Low-Dose Granulocyte Colony-Stimulating Factor in Acute Ischemic Stroke by Mizuma, Atsushi, MD, PhD, Yamashita, Toru, MD, PhD, Kono, Syoichiro, MD, PhD, Nakayama, Taira, MD, Baba, Yasuhiko, MD, PhD, Itoh, Shinji, MD, PhD, Asakura, Kunihiko, MD, PhD, Niimi, Yoshiki, MD, PhD, Asahi, Takashi, MD, PhD, Kanemaru, Kazuya, MD, PhD, Mutoh, Tatsuro, MD, PhD, Kuroda, Satoshi, MD, PhD, Kinouchi, Hiroyuki, MD, PhD, Abe, Koji, MD, PhD, Takizawa, Shunya, MD, PhD

“…Background Granulocyte colony-stimulating factor (G-CSF) has shown neuroprotective and neurogenerative activities in experimental studies, and our previous…”
Get full text

Differentiation of cancer from atrial fibrillation in patients with acute multifocal stroke by Ito, Shinji, MD, PhD, Ueda, Akihiro, MD, PhD, Murate, Kenichiro, MD, Hirota, Seiko, MD, Fukui, Takao, MD, Ishikawa, Tomomasa, MD, Shima, Sayuri, MD, PhD, Hikichi, Chika, MD, Mizutani, Yasuaki, MD,PhD, Kizawa, Madoka, MD, PhD, Asakura, Kunihiko, MD, PhD, Mutoh, Tatsuro, MD, PhD

“…Abstract Objective. Acute multifocal embolic infarction (AMEI) is conventionally caused by etiologies such as cardioembolism due to atrial fibrillation (Af),…”
Get full text

Histone deacetylase inhibitor attenuates neurotoxicity of clioquinol in PC12 cells by Fukui, Takao, Asakura, Kunihiko, Hikichi, Chika, Ishikawa, Tomomasa, Murai, Rie, Hirota, Seiko, Murate, Ken-ichiro, Kizawa, Madoko, Ueda, Akihiro, Ito, Shinji, Mutoh, Tatsuro

“…Highlights • Clioquinol reduced acetylated histones in PC12 cells. • Histone deacetylase (HDAC) inhibitor upregulated acetylated histones. • HDAC inhibitor…”
Get full text

Retrospective analysis of parkinsonian patients exhibiting normal 123I-MIBG cardiac uptake by Mizutani, Yasuaki, Ito, Shinji, Murate, Kenichiro, Hirota, Seiko, Fukui, Takao, Hikichi, Chika, Ishikawa, Tomomasa, Shima, Sayuri, Ueda, Akihiro, Kizawa, Madoka, Asakura, Kunihiko, Mutoh, Tatsuro

“…Although most patients with Parkinson's disease (PD) show decreased cardiac 123I-metaiodobenzylguanidine (MIBG) uptake, some exhibit normal uptake. We…”
Get full text

Neurological involvement in Wegener's granulomatosis by Asakura, Kunihiko, Muto, Tatsuro

“…Abstract Wegener's granulomatosis is a rare autoimmune disease associated with granulomatous inflammation and anti-neutrophil cytoplasmic antibody…”
Get more information

Voriconazole-responsive Disseminated Nodular Lesions on Spinal MRI by Hirota, Seiko, Ito, Shinji, Fukui, Takao, Murate, Kenichiro, Shima, Sayuri, Kizawa, Madoka, Ueda, Akihiro, Asakura, Kunihiko, Mutoh, Tatsuro

“…A 74-year-old woman was hospitalized due to dysuria, weakness and dysesthesia of the lower extremities. She was in an immunosuppressed state following the…”
Get full text

Transient Splenial Lesion of the Corpus Callosum in H1N1 Influenza Virus-Associated Encephalitis/Encephalopathy by Ito, Shinji, Shima, Sayuri, Ueda, Akihiro, Kawamura, Naoki, Asakura, Kunihiko, Mutoh, Tatsuro

“…A 26-year-old man was admitted to our hospital because of high fever, drowsiness, memory disturbance, and disorientation due to H1N1 influenza virus-associated…”
Get full text

Clioquinol inhibits NGF-induced Trk autophosphorylation and neurite outgrowth in PC12 cells by Asakura, Kunihiko, Ueda, Akihiro, Kawamura, Naoki, Ueda, Madoka, Mihara, Takateru, Mutoh, Tatsuro

“…Abstract Clioquinol is considered to be a causative agent of subacute myelo-optico neuropathy (SMON), although the pathogenesis of SMON is yet to be…”
Get full text

Abnormal cross‐talk between mutant presenilin 1 (I143T, G384A) and glycosphingolipid biosynthesis by Mutoh, Tatsuro, Kawamura, Naoki, Hirabayashi, Yoshio, Shima, Sayuri, Miyashita, Tadayuki, Ito, Shinji, Asakura, Kunihiko, Araki, Wataru, Cazzaniga, Emanuela, Muto, Eri, Masserini, Massimo

“…ABSTRACT Mutations in the presenilin 1 (PS1) gene are associated with early onset familial Alzheimer's disease (FAD). In this study, we found that the…”
Get full text

Human Monoclonal Antibodies Reactive to Oligodendrocytes Promote Remyelination in a Model of Multiple Sclerosis by Warrington, Arthur E., Asakura, Kunihiko, Bieber, Allan J., Ciric, Bogoljub, Van Keulen, Virginia, Kaveri, Srini V., Kyle, Robert A., Pease, Larry R., Rodriguez, Moses

“…Promoting remyelination, a major goal of an effective treatment for demyelinating diseases, has the potential to protect vulnerable axons, increase conduction…”
Get full text

Depressive state as an initial symptom for subdural abscess by Fukui, Takao, Ueda, Akihiro, Murate, Ken‐ichiro, Hikichi, Chika, Ito, Shinji, Asakura, Kunihiko, Mutoh, Tatsuro

“…A 47‐year‐old man with a subdural abscess was initially diagnosed with endogenous depression at another hospital. He presented with a chronic illness, but…”
Get full text

Theiler's Murine Encephalomyelitis Virus Leader Protein Amino Acid Residue 57 Regulates Subgroup-Specific Virus Growth on BHK-21 Cells by TAKANO-MARUYAMA, Masumi, OHARA, Yoshiro, ASAKURA, Kunihiko, OKUWA, Takako

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Expression of L protein of Theiler's murine encephalomyelitis virus in the chronic phase of infection by Asakura, Kunihiko, Murayama, Harunobu, Himeda, Toshiki, Ohara, Yoshiro

“…1 Department of Microbiology, Kanazawa Medical University, Ishikawa 920-0293, Japan 2 Division of Pathology, Sendai City Hospital, Miyagi 984-0075, Japan…”
Get full text

Novel therapeutic approach for Alzheimer’s disease by removing amyloid β protein from the brain with an extracorporeal removal system by Kawaguchi, Kazunori, Kitaguchi, Nobuya, Nakai, Shigeru, Murakami, Kazutaka, Asakura, Kunihiko, Mutoh, Tatsuro, Fujita, Yoshiro, Sugiyama, Satoshi

“…The accumulation of amyloid beta (Aβ) protein in the brain reflects the cognitive impairment noted in Alzheimer’s disease. Recent studies have shown that brain…”
Get full text

Leader (L) and L proteins of Theiler's murine encephalomyelitis virus (TMEV) and their regulation of the virus' biological activities by Takano-Maruyama, Masumi, Ohara, Yoshiro, Asakura, Kunihiko, Okuwa, Takako

“…Theiler's murine encephalomyelitis virus (TMEV) is divided into two subgroups on the basis of their different biological activities. GDVII subgroup strains…”
Get full text

Acute Autonomic, Sensory and Motor Neuropathy: Successful Treatment with IVIg by Ueda, Akihiro, Asakura, Kunihiko, Mihara, Takateru, Hara, Hideo, Ueda, Madoka, Miyashita, Tadayuki, Mutoh, Tatsuro

“…Acute autonomic, sensory and motor neuropathy (AASMN) is a rare peripheral nerve disorder characterized by prominent dysautonomia with somatic sensory and…”
Get full text

Epitope-Tagged L Protein of Theiler's Murine Encephalomyelitis Virus Is Expressed in the Central Nervous System in the Acute Phase of Infection by Asakura, Kunihiko, Murayama, Harunobu, Himeda, Toshiki, Ohara, Yoshiro

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text