Search Results - "Asakawa, Jun"

Characteristics of induced mutations in offspring derived from irradiated mouse spermatogonia and mature oocytes by Satoh, Yasunari, Asakawa, Jun-ichi, Nishimura, Mayumi, Kuo, Tony, Shinkai, Norio, Cullings, Harry M., Minakuchi, Yohei, Sese, Jun, Toyoda, Atsushi, Shimada, Yoshiya, Nakamura, Nori, Uchimura, Arikuni

“…The exposure of germ cells to radiation introduces mutations in the genomes of offspring, and a previous whole-genome sequencing study indicated that the…”
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Radiation-Induced Deletions in Mouse Spermatogonia are Usually Large (over 200 kb) and Contain Little Sequence Similarity at the Junctions by Kodaira, Mieko, Asakawa, Jun-ichi, Nakamura, Nori

“…Ionizing radiation can induce mutations, and the majority of radiation-induced mutations in mammalian cells are deletions. The most critical types of…”
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Mutagenic Effects of Ionizing Radiation on Immature Rat Oocytes by Asakawa, Jun-ichi, Kamiguchi, Yujiroh, Kamiya, Kenji, Nakamura, Nori

“…Estimates of genetic risks from radiation delivered to humans are derived largely from mouse studies. In males, the target is spermatogonia and a large amount…”
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Non‐homologous end joining‐mediated functional marker selection for DNA cloning in the yeast Kluyveromyces marxianus by Hoshida, Hisashi, Murakami, Nobutada, Suzuki, Ayako, Tamura, Ryoko, Asakawa, Jun, Abdel‐Banat, Babiker M. A., Nonklang, Sanom, Nakamura, Mikiko, Akada, Rinji

“…The cloning of DNA fragments into vectors or host genomes has traditionally been performed using Escherichia coli with restriction enzymes and DNA ligase or…”
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Genome-Wide Deletion Screening with the Array CGH Method in Mouse Offspring Derived from Irradiated Spermatogonia Indicates that Mutagenic Responses are Highly Variable among Genes by Asakawa, Jun-ichi, Kodaira, Mieko, Miura, Akiko, Tsuji, Takahiro, Nakamoto, Yoshiko, Imanaka, Masaaki, Kitamura, Jun, Cullings, Harry, Nishimura, Mayumi, Shimada, Yoshiya, Nakamura, Nori

“…Until the end of the 20th century, mouse germ cell data on induced mutation rates, which were collected using classical genetic methods at preselected specific…”
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The Genetic Risk in Mice from Radiation: An Estimate of the Mutation Induction Rate per Genome by Asakawa, Jun-ichi, Kodaira, Mieko, Cullings, Harry M., Katayama, Hiroaki, Nakamura, Nori

“…Restriction Landmark Genome Scanning (RLGS) is a method that uses end-labeled 32P NotI sites that are mostly associated with coding genes to visualizes…”
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Restriction landmark genome scanning for the detection of mutations by Asakawa, Jun-ichi

“…There is a continuing need for more efficient methods to examine mutations in humans and other species resulting from exposures to environmental toxins and…”
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Estimation of Mutation Induction Rates in AT-Rich Sequences Using a Genome Scanning Approach after X Irradiation of Mouse Spermatogonia by Asakawa, Jun-ichi, Nakamura, Nori, Katayama, Hiroaki, Cullings, Harry M.

“…Asakawa, J., Nakamura, N., Katayama, H. and Cullings, H. M. Estimation of Mutation Induction Rates in AT-Rich Sequences Using a Genome Scanning Approach after…”
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Virtual genome scan: a tool for restriction landmark-based scanning of the human genome by Rouillard, J M, Erson, A E, Kuick, R, Asakawa, J, Wimmer, K, Muleris, M, Petty, E M, Hanash, S

“…There is substantial interest in implementing technologies that allow comparisons of whole genomes of individuals and of tissues and cell populations…”
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A Genome Scanning Approach to Assess the Genetic Effects of Radiation in Mice and Humans by Asakawa, Jun-ichi, Kuick, Rork, Kodaira, Mieko, Nakamura, Nori, Katayama, Hiroaki, Pierce, Donald, Funamoto, Sachiyo, Preston, Dale, Satoh, Chiyoko, Neel, James V., Hanash, Samir

“…Asakawa, J., Kuick, R., Kodaira, M., Nakamura, N., Katayama, H., Pierce, D., Funamoto, S., Preston, D., Satoh, C., Neel, J. V. and Hanash, S. A Genome Scanning…”
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Demethylation of repetitive DNA sequences in neuroblastoma by Thoraval, Didier, Asakawa, Jun-ichi, Wimmer, Katharina, Kuick, Rork, Lamb, Barbara, Richardson, Bruce, Ambros, Peter, Glover, Thomas, Hanash, Samir

“…Altered genomic methylcytosine content has been described for a number of tumor types, including neuroblastoma. However, it remains to be determined for…”
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Two-Dimensional Complementary Deoxyribonucleic Acid Electrophoresis Revealing Up-Regulated Human Epididymal Protein-1 and Down-Regulated CL-100 in Thyroid Papillary Carcinoma by Asakawa, Jun-ichi, Kodaira, Mieko, Ishikawa, Naofumi, Hirai, Yuko, Nagataki, Shigenobu, Moatamed, Farhad, Sugawara, Masahiro

“…Two-dimensional cDNA electrophoresis was used to analyze gene expressions in papillary carcinoma and normal tissue of thyroid glands. Pooled thyroid tissues…”
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Chimerism in Humans after Intragenic Recombination at the Haptoglobin Locus during Early Embryogenesis by Asakawa, Jun-ichi, Kodaira, Mieko, Nakamura, Nori, Satoh, Chiyoko, Fujita, Mikio

“…The human haptoglobin (HP) HP*2 allele contains a 1.7-kilobase (kb) intragenic duplication that arose after a unique nonhomologous recombination between the…”
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Genetic Analysis of Children of Atomic Bomb Survivors by Satoh, Chiyoko, Takahashi, Norio, Asakawa, Jun-ichi, Kodaira, Mieko, Kuick, Rork, Hanash, Samir M., Neel, James V.

“…Studies are under way for the detection of potential genetic effects of atomic bomb radiation at the DNA level in the children of survivors. In a pilot study,…”
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Studies of the Inheritance of Human Ribosomal DNA Variants Detected in Two-Dimensional Separations of Genomic Restriction Fragments by Kuick, R, Asakawa, J. I, Neel, J. V, Kodaira, M, Satoh, C, Thoraval, D, Gonzalez, I. L, Hanash, S. M

“…We have investigated the variation in human ribosomal DNA repeat units as revealed in two-dimensional electrophoretic separates of genomic restriction…”
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High yield of restriction fragment length polymorphisms in two-dimensional separations of human genomic DNA by Kuick, Rork, Asakawa, Jun-Ichi, Neel, James V., Satoh, Chiyoko, Hanash, Samir M.

“…We have investigated the extent to which restriction fragment length polymorphism can be detected by two-dimensional electrophoresis of end-labeled genomic…”
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Genetic Variation Detected by Quantitative Analysis of End-Labeled Genomic DNA Fragments by Asakawa, Jun-ichi, Kuick, Rork, Neel, James V., Kodaira, Mieko, Satoh, Chiyoko, Hanash, Samir M.

“…The continuing efforts to evaluate specific human populations for altered germinal mutation rates would profit from more efficient and more specific approaches…”
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Accurate and Rapid Detection of Heterozygous Carriers of a Deletion by Combined Polymerase Chain Reaction and High-Performance Liquid Chromatography by Asakawa, Jun-Ichi, Satoh, Chiyoko, Yamasaki, Yosuke, Chen, Shi-Han

“…We have developed a technique to detect accurately heterozygous carriers of a deletion. Specific target sequences were amplified by the polymerase chain…”
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CD2 expression in murine B cell lineage by Yagita, H, Nakamura, T, Asakawa, J, Matsuda, H, Tansyo, S, Iigo, Y, Okumura, K

“…CD2 expression in murine B cell lineage was examined by flow cytometric and immunoprecipitation studies with anti-murine CD2 mAb and by Northern blot analysis…”
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Two-dimensional gel studies of genetic variation in the plasma proteins of Amerindians and Japanese by ASAKAWA, J.-I, TAKAHASHI, N, ROSENBLUM, B. B, NEEL, J. V

“…Genetic variation has been studied in plasma samples from 107 Amerindian children and their parents, and 110 Japanese children and their parents by means of…”
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